Brainstem injury in victims of sudden intrauterine death syndrome (SIUDS) and sudden infant death syndrome (SIDS)

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AJCC 8th Edition (2017) versus AJCC 7th Edition (2010) in thin melanoma staging

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The utility of the 3D imaging software in the macroscopic rendering of complex gynecologic specimens

A new generation of three dimensional (3D) imaging software for the anatomical rendering of the human body, and related surgical pathologies, is postulated. Its practical application is underlined

Mezzi di indagine per la diagnosi di laboratorio di HTLV

corso di laurea in Tecnico di laboratorio biomedic

A new lipomatous entity: The cavernous angiolipoma of the subcutis

Angiolipoma is a benign soft-tissue tumor which combines the morphological features of lipoma with those of hemangioma. The ratio of lipomatous and vascular components is variable, reaching the latter the highest percentage in the cellular variant of the tumor. Microscopically, the tumor consists of mature adipocytes separated by a branching network of small vessels, which often contain fibrin thrombi. We present the first literary description of cavernous angiolipoma of the subcutis in a 75-year-old man, delivering a new lipomatous entity. This entity should be reserved to subcutaneous angiolipoma with very large vascular gaps, haphazardly arranged and engorged by blood. The differential diagnosis of this tumor depends on vascular density: the hypovascular tumor can be mistaken with a common lipoma, while the hypervascular lesion should be distinguished from cavernous hemangioma and related variants, intramuscular hemangioma, spindle cell hemangioma, arteriovenous and venous malformations and Kaposi's sarcoma. Histopathogenetic theories about cavernous angiolipoma of the subcutis include a possible differentiation from a pluripotent mesenchymal cell into both lipomatous and angiomatous counterparts, due to inflammation or trauma, and a progressive development from a congenital malformation / benign hamartoma. In support of the latter thesis, there is a 5-10% familial incidence of classic angiolipoma and the frequent presence of many mast cells inside the tumor. Moreover, about a third of all angiolipomas express androgen receptors and this datum leads to suspect a hormonal influence in the development of these subcutaneous tumors