Angioleiomyoma affecting the lips : report of 3 cases and review of the literature

Angioleiomyoma is an uncommon benign soft tissue tumor usually found in the lower extremities and rarely observed in oral tissues. It is microscopically characterized as a proliferation of smooth muscle cells intermingled with abundant vascular channels. Oral angioleiomyomas affect mostly the lips, palate, buccal mucosa and tongue, and appears as a submucosal painless nodule. Upper lip is seldom affected and only few cases have been reported. We report three additional cases of angioleiomyoma affecting the lips of elderly patients. All lesions were asymptomatic and presented as submucosal nodules of approximately 1cm. Microscopic analysis on H and E sections revealed similar pattern in all cases, showing well-circumscribed and encapsulated tumors characterized by proliferation of smooth muscle cells and large amount of wide vascular spaces of varying sizes. Most tumor cells were immunoreactive for ?-smooth muscle actin, desmin and HHF-35. CD34 was also positive on the endothelial cells. All patients were surgically treated and no recurrence was observed so far. The oral pathologists and clinicians should consider this entity when assessing nodular lesions on upper lip. © Medicina Oral S. L

C-reactive protein as an inflammatory marker of acute infections outside intensive care settings: case report and evidence-based literature review

We present the clinical case of a 76-year-old woman with delirium causedby multiple factors, including pneumonia. Although this type of case is quitecommon in clinical practice, it provides us with an opportunity to discusslaboratory testing in this context, with a special focus on the role of C-reactiveprotein (CRP). We present data regarding the requests for determination ofserum CRP levels at the University of São Paulo University Hospital overthe past few years. We also present a review of the medical literature on thetopic, as well as clinical epidemiology concepts related to the impact that CRPtesting has on the medical decision-making process

ClimCast - The embryo of a warning network for the chestnut crop

As projeções de clima para o futuro em Portugal sugerem mudanças significativas nos valores médios mensais e anuais dos elementos climáticos (e.g., temperatura do ar e precipitação), na distribuição espaço temporal, na magnitude e frequência dos eventos extremos, tornando imprescindível instalar um sistema de monitorização climática que permita melhorar o conhecimento da relação entre as condições meteorológicas e o castanheiro sendo o embrião de uma futura rede de avisos para a cultura. O sistema está constituído por 7 soutos demonstração (SD), área total 5000 m2, instalados em 2018: Salgueiros- Vinhais; Parada – Bragança; Lagoa – Vila Pouca de Aguiar; Carrazedo Montenegro – Valpaços; Refoios do Lima – Ponte de Lima; Penela da Beira – Penedono; Porto da Espada – Marvão. Em cada SD estão instaladas as seguintes variedades: DOP castanha da Terra Fria (Longal e Boaventura), DOP Castanha da Padrela (Judia e Cota), DOP castanha dos Soutos da Lapa (Martaínha), DOP Castanha de Marvão/Portalegre (Colarinha e Bária) e Minho (Amarelal), mais duas variedades cultivadas em Espanha: Parede na Galiza e Pilonga na Serra de Ronda (Andaluzia). Cada SD tem instalada uma estação meteorológica. A rede é completada com o Banco de Germoplasma da UTAD, que forneceu material de enxertia para os SD: Folhadela - Vila Real.Financiado pelo Fundo Europeu Agrícola de Desenvolvimento Rural (FEADER) e pelo Estado Português no âmbito da Ação 1.1 «Grupos Operacionais», integrada na Medida 1. «Inovação» do PDR 2020 – Programa de Desenvolvimento Rural do Continente. Refª ClimCast - PDR2020-101-032043.info:eu-repo/semantics/publishedVersio