10 research outputs found

    Određivanje ukupnih polifenola te indeksa posmeđenja međimurskih vina PuÅ”ipel

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    PuÅ”ipel, (sinonim moslavec) je sorta bijelog grožđa i vina koja se smatra jednom od najvažnijih sorata za razvoj vinarstva i vinogradarstva u Međimurju. U ovom radu detaljno se opisuje izabrana sorta puÅ”ipel; povijest proizvodnje, proizvodnja danas, tehnologija proizvodnje bijelih vina te senzorske karakteristike. U sklopu eksperimentalnog dijela određen je sastav ukupnih polifenola te indeks posmeđenja u puÅ”ipel vinima pet različitih proizvođača iz Međimurja. Među uzorcima primijećene su male razlike u sadržaju polifenola i indeksu posmeđenja Å”to je vjerojatno rezultat različitih vinogradarskih tehnika tijekom same proizvodnje grožđa, razlike u tehnologiji proizvodnje, ali i skladiÅ”tenjenju vina

    KADROVIRANJE U PODUZEĆU NA PRIMJERU ZAGREBAČKA PIVOVARA

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    Poduzeće svoj cilj ostvaruje ljudskim radom koji prethodno i organizira zbog djelotvornosti i uspjeha. U danaÅ”nje vrijeme radnike treba smatrati kao partnere poduzeća te menadžment treba uvidjeti njihove potencijale kako bi čim viÅ”e svojim djelotvornim radom doprinosili uspjehu i napretku poduzeća. Služba koja se bavi ljudima odnosno kadrovima u poduzeću je kadrovska služba. Funkcija kadrovske službe je ključna za opstanak i razvoj poduzeća jer zahtijeva analizu posla, radnika, procesa, regrutiranje, selekciju, usavrÅ”avanje i unapređenje kadrova. Cilj ovoga rada je pobliže objasniti pojam i proces kadroviranja te njegovu konkretnu primjenu u poduzeću Zagrebačka pivovara.The company achives goals by human work whick previously they need to organize for efficinency and success. Nowdays, workers should be considered as business partners and management needs to see their potential so they can progress and success by their work. The staffing department in the company is the personnel department. Staffing is key to survive and eneterprise development because it requres job, employee, process analysis, recruitment, selection, improvement and improvement of staff. Main purpose of this paper is to explain the concept and process of staffing and its specific application in the Zagrebačka pivovara company

    Analysis of the supply of tourist agencies in continental Croatia

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    U ovom se radu razrađuje tematika turističkih agencija, počevÅ”i od povijesnog razvoja turizma u svijetu, osnutka prvih turističkih agencija pa sve do razvoja i suvremenih adaptacija turističkih agencija na tehnologiju i trendove. Opisuje se glavni proizvod čijom se prodajom agencije bave, turistički aranžman te ponuda turističkih proizvoda s obzirom na suvremene trendove na tržiÅ”tu. Glavna tematika ovog zavrÅ”nog rada je analiza poslovanja turističkih agencija u kontinentalnom dijelu Hrvatske, s podjelom na tri glavne regije: Sjeverne Hrvatske, Panonske Hrvatske te Grada Zagreba. Za svaku regiju u obzir je uzeto nekoliko turističkih agencija te njihov predmet poslovanja, analizirana je ponuda web stranice za svaku pojedinu agenciju te iz toga izveden zaključak za obrađenu regiju. Ponuda agencija i njihov način poslovanja uspoređen je s razvojem trendova na tržiÅ”tu i utvrđeni su prednosti i nedostaci istog.This work elaborates the topic of travel agencies, starting from the historical development of tourism in the world, the foundation of the first travel agencies, all the way to the development and modern adaptations of travel agencies to technology and trends. The main product sold by the agencies is described, as well as the tourist arrangement and the offer of tourist products regarding contemporary trends on the market. The main subject of this final thesis is the analysis of the business of travel agencies in the continental part of Croatia, divided into three main regions: Northern Croatia, Pannonian Croatia, and the City of Zagreb. For each region, several travel agencies and their business were considered, the website offer for each individual agency was analyzed, and a conclusion was drawn from this for the treated region. The offer of the agencies and their way of doing business was compared with the development of trends on the market and its advantages and disadvantages were determined

    KADROVIRANJE U PODUZEĆU NA PRIMJERU ZAGREBAČKA PIVOVARA

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    Poduzeće svoj cilj ostvaruje ljudskim radom koji prethodno i organizira zbog djelotvornosti i uspjeha. U danaÅ”nje vrijeme radnike treba smatrati kao partnere poduzeća te menadžment treba uvidjeti njihove potencijale kako bi čim viÅ”e svojim djelotvornim radom doprinosili uspjehu i napretku poduzeća. Služba koja se bavi ljudima odnosno kadrovima u poduzeću je kadrovska služba. Funkcija kadrovske službe je ključna za opstanak i razvoj poduzeća jer zahtijeva analizu posla, radnika, procesa, regrutiranje, selekciju, usavrÅ”avanje i unapređenje kadrova. Cilj ovoga rada je pobliže objasniti pojam i proces kadroviranja te njegovu konkretnu primjenu u poduzeću Zagrebačka pivovara.The company achives goals by human work whick previously they need to organize for efficinency and success. Nowdays, workers should be considered as business partners and management needs to see their potential so they can progress and success by their work. The staffing department in the company is the personnel department. Staffing is key to survive and eneterprise development because it requres job, employee, process analysis, recruitment, selection, improvement and improvement of staff. Main purpose of this paper is to explain the concept and process of staffing and its specific application in the Zagrebačka pivovara company

    Određivanje ukupnih polifenola te indeksa posmeđenja međimurskih vina PuÅ”ipel

    No full text
    PuÅ”ipel, (sinonim moslavec) je sorta bijelog grožđa i vina koja se smatra jednom od najvažnijih sorata za razvoj vinarstva i vinogradarstva u Međimurju. U ovom radu detaljno se opisuje izabrana sorta puÅ”ipel; povijest proizvodnje, proizvodnja danas, tehnologija proizvodnje bijelih vina te senzorske karakteristike. U sklopu eksperimentalnog dijela određen je sastav ukupnih polifenola te indeks posmeđenja u puÅ”ipel vinima pet različitih proizvođača iz Međimurja. Među uzorcima primijećene su male razlike u sadržaju polifenola i indeksu posmeđenja Å”to je vjerojatno rezultat različitih vinogradarskih tehnika tijekom same proizvodnje grožđa, razlike u tehnologiji proizvodnje, ali i skladiÅ”tenjenju vina

    Analysis of the supply of tourist agencies in continental Croatia

    No full text
    U ovom se radu razrađuje tematika turističkih agencija, počevÅ”i od povijesnog razvoja turizma u svijetu, osnutka prvih turističkih agencija pa sve do razvoja i suvremenih adaptacija turističkih agencija na tehnologiju i trendove. Opisuje se glavni proizvod čijom se prodajom agencije bave, turistički aranžman te ponuda turističkih proizvoda s obzirom na suvremene trendove na tržiÅ”tu. Glavna tematika ovog zavrÅ”nog rada je analiza poslovanja turističkih agencija u kontinentalnom dijelu Hrvatske, s podjelom na tri glavne regije: Sjeverne Hrvatske, Panonske Hrvatske te Grada Zagreba. Za svaku regiju u obzir je uzeto nekoliko turističkih agencija te njihov predmet poslovanja, analizirana je ponuda web stranice za svaku pojedinu agenciju te iz toga izveden zaključak za obrađenu regiju. Ponuda agencija i njihov način poslovanja uspoređen je s razvojem trendova na tržiÅ”tu i utvrđeni su prednosti i nedostaci istog.This work elaborates the topic of travel agencies, starting from the historical development of tourism in the world, the foundation of the first travel agencies, all the way to the development and modern adaptations of travel agencies to technology and trends. The main product sold by the agencies is described, as well as the tourist arrangement and the offer of tourist products regarding contemporary trends on the market. The main subject of this final thesis is the analysis of the business of travel agencies in the continental part of Croatia, divided into three main regions: Northern Croatia, Pannonian Croatia, and the City of Zagreb. For each region, several travel agencies and their business were considered, the website offer for each individual agency was analyzed, and a conclusion was drawn from this for the treated region. The offer of the agencies and their way of doing business was compared with the development of trends on the market and its advantages and disadvantages were determined

    Analysis of the supply of tourist agencies in continental Croatia

    No full text
    U ovom se radu razrađuje tematika turističkih agencija, počevÅ”i od povijesnog razvoja turizma u svijetu, osnutka prvih turističkih agencija pa sve do razvoja i suvremenih adaptacija turističkih agencija na tehnologiju i trendove. Opisuje se glavni proizvod čijom se prodajom agencije bave, turistički aranžman te ponuda turističkih proizvoda s obzirom na suvremene trendove na tržiÅ”tu. Glavna tematika ovog zavrÅ”nog rada je analiza poslovanja turističkih agencija u kontinentalnom dijelu Hrvatske, s podjelom na tri glavne regije: Sjeverne Hrvatske, Panonske Hrvatske te Grada Zagreba. Za svaku regiju u obzir je uzeto nekoliko turističkih agencija te njihov predmet poslovanja, analizirana je ponuda web stranice za svaku pojedinu agenciju te iz toga izveden zaključak za obrađenu regiju. Ponuda agencija i njihov način poslovanja uspoređen je s razvojem trendova na tržiÅ”tu i utvrđeni su prednosti i nedostaci istog.This work elaborates the topic of travel agencies, starting from the historical development of tourism in the world, the foundation of the first travel agencies, all the way to the development and modern adaptations of travel agencies to technology and trends. The main product sold by the agencies is described, as well as the tourist arrangement and the offer of tourist products regarding contemporary trends on the market. The main subject of this final thesis is the analysis of the business of travel agencies in the continental part of Croatia, divided into three main regions: Northern Croatia, Pannonian Croatia, and the City of Zagreb. For each region, several travel agencies and their business were considered, the website offer for each individual agency was analyzed, and a conclusion was drawn from this for the treated region. The offer of the agencies and their way of doing business was compared with the development of trends on the market and its advantages and disadvantages were determined

    Stress Hyperglycaemia Indicates Embolus Size and Localization in Patients with Acute Pulmonary Embolism

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    Objective. Acute pulmonary embolism is a life-threatening form of venous thromboembolism often causing stress hyperglycaemia. The aim of this study was to determine the prognostic value of stress hyperglycaemia in acute pulmonary embolism, providing new insights into the presumed embolus size and localization, clinical parameters (Pulmonary Embolism Severity Index, PESI), and in-hospital mortality. Design and Methods. Among a total of 95,454 patients referred to the Emergency Department of the Sestre Milosrdnice University Hospital Centre between 2014 and 2016, all patients with acute pulmonary embolism were included into this observational cohort study. The study group consisted of 190 patients aged 25ā€“96. Relevant patient history, clinical data, and laboratory findings were collected during the entire hospitalization period. Data were analyzed for the entire group of patients, as well as separately for patients without diabetes, using the Fisher exact test and logistic regression. Results. Analysis of embolus localization as an indirect parameter of embolus size showed that patients with stress hyperglycaemia more often had emboli located in proximal parts of the pulmonary circulation (i.e., main artery or lobar branches) (p<0.05). Furthermore, stress hyperglycaemia correlated with PESI score and diabetes (p<0.05) in the entire patient group. Stress hyperglycaemia showed independent association with in-hospital mortality in patients (p<0.05). Conclusion. Stress hyperglycaemia in patients with acute pulmonary embolism is associated with embolus localization in larger arteries of the pulmonary circulation and higher PESI score and therefore could serve as an independent in-hospital mortality predictor

    Emerging roles for CNS fibroblasts in health, injury and disease.

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    Recent transcriptomic, histological and functional studies have begun to shine light on the fibroblasts present in the meninges, choroid plexus and perivascular spaces of the brain and spinal cord. Although the origins and functions of CNS fibroblasts are still being described, it is clear that they represent a distinct cell population, or populations, that have likely been confused with other cell types on the basis of the expression of overlapping cellular markers. Recent work has revealed that fibroblasts play crucial roles in fibrotic scar formation in the CNS after injury and inflammation, which have also been attributed to other perivascular cell types such as pericytes and vascular smooth muscle cells. In this Review, we describe the current knowledge of the location and identity of CNS perivascular cell types, with a particular focus on CNS fibroblasts, including their origin, subtypes, roles in health and disease, and future areas for study

    CNS fibroblasts form a fibrotic scar in response to immune cell infiltration.

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    Fibrosis is a common pathological response to inflammation in many peripheral tissues and can prevent tissue regeneration and repair. Here, we identified persistent fibrotic scarring in the CNS following immune cell infiltration in the experimental autoimmune encephalomyelitis (EAE) mouse model of multiple sclerosis. Using lineage tracing and single-cell sequencing in EAE, we determined that the majority of the fibrotic scar is derived from proliferative CNS fibroblasts, not pericytes or infiltrating bone marrow-derived cells. Ablating proliferating fibrotic cells using cell-specific expression of herpes thymidine kinase led to an increase in oligodendrocyte lineage cells within the inflammatory lesions and a reduction in motor disability. We further identified that interferon-gamma pathway genes are enriched in CNS fibrotic cells, and the fibrotic cell-specific deletion of Ifngr1 resulted in reduced fibrotic scarring in EAE. These data delineate a framework for understanding the CNS fibrotic response
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