Research360: Jisc Final Report

The Research360 project aimed to develop human and technical infrastructure to facilitate management of the University of Bath’s research data, in response to increasing external drivers for access to publicly funded research outputs. The project successfully laid the foundations for an embedded data management service. This included a roadmap setting out how compliance with the EPSRC’s expectations for research data will be achieved. To support the implementation of this Roadmap for EPSRC, a new, high-level Research Data Sustainability Group was established.The project created two new data management roles within the University and, by delivery of a successful draft Business Case, succeeded in permanently retaining these essential, central roles. Supporting this draft Business Case was a range of guidance, aimed at enabling other institutions to develop similar business cases. This guidance demonstrated how best practice in research data management would benefit the institution, external collaborators and society and also how it would contribute to the Research Excellence Framework (REF) 2014. The project found that responding to researcher demand for training, storage and data publication was a strong motivator of continuing investment in data management activities.Through an institution-wide survey, the project identified a lack of central policy and co-ordination, and difficulties storing and sharing research active data, as main priorities for the University to address. Research360 therefore developed a draft data management policy for the University and documented the process in a set of guidelines aimed at the wider community. The project redesigned the University’s data management website, as a focal point for researchers searching for help. It also developed specific guidance on the storage of research active data. This guidance was supported by the development of a new training workshop and an online training module, designed to give researchers an introduction to the issues and responsibilities of research data management. Research360 explored integrating the Sakai virtual research environment with the SWORD2 deposit protocol and reported the experience and recommendations to the Sakai community. The project also worked with EPrints Services to develop a pilot institutional data repository, which will facilitate cataloguing and publishing research data.Through a broad dissemination programme and close coordination with a range of stakeholders across the University, the Research360 project team established a network of local, national and international advisors, who will prove essential partners as the ongoing data management service continues to develop.The project concluded that establishment of a pilot data management service requires considerable resource and that many aspects of data management require further investigation. As such, the project strongly recommends that Jisc continue to support programmes and activities in research data management

Prophase-Specific Perinuclear Actin Coordinates Centrosome Separation and Positioning to Ensure Accurate Chromosome Segregation

Centrosome separation in late G2/ early prophase requires precise spatial coordination that is determined by a balance of forces promoting and antagonizing separation. The major effector of centrosome separation is the kinesin Eg5. However, the identity and regulation of Eg5-antagonizing forces is less well characterized. By manipulating candidate components, we find that centrosome separation is reversible and that separated centrosomes congress toward a central position underneath the flat nucleus. This positioning mechanism requires microtubule polymerization, as well as actin polymerization. We identify perinuclear actin structures that form in late G2/early prophase and interact with microtubules emanating from the centrosomes. Disrupting these structures by breaking the interactions of the linker of nucleoskeleton and cytoskeleton (LINC) complex with perinuclear actin filaments abrogates this centrosome positioning mechanism and causes an increase in subsequent chromosome segregation errors. Our results demonstrate how geometrical cues from the cell nucleus coordinate the orientation of the emanating spindle poles before nuclear envelope breakdown

Active Microrheology of Networks Composed of Semiflexible Polymers. II. Theory and comparison with simulations

Building on the results of our computer simulation (ArXiv cond-mat/0503573)we develop a theoretical description of the motion of a bead, embedded in a network of semiflexible polymers, and responding to an applied force. The theory reveals the existence of an osmotic restoring force, generated by the piling up of filaments in front of the moving bead and first deduced through computer simulations. The theory predicts that the bead displacement scales like x ~ t^alfa with time, with alfa=0.5 in an intermediate- and alfa=1 in a long-time regime. It also predicts that the compliance varies with concentration like c^(-4/3) in agreement with experiment.Comment: 18 pages and 2 figure

Making and Sharing the Commons: Reimagining ‘the West’ as Riverlands, Sydney through a Dialogue between Design and Ethnography

Scholars from the social sciences and humanities are increasingly seeking to improve the relevance and social impact of their research beyond the academy. In this context, ‘designerly’ thinking and methods are being drawn on to inform social change agendas, and a range of new relationships and collaborations are forming around this node of activity. This article critically reflects on this trajectory through a dialogue between ethnography, design and theoretical principles from anthropology and human geography

Exploring the use of new school buildings through post-occupancy evaluation and participatory action research

This paper presents the results of the development and testing of an integrated post-occupancy evaluation (POE) approach for teachers, staff, pupils and community members using newly constructed school buildings. It focusses on three cases of UK secondary schools, demonstrating how users can be inspired to engage with the problems of school design and energy use awareness. The cases provided new insights into the engagement of school teachers, staff and young people regarding issues of sustainability, management, functional performance and comfort. The integrative approach adopted in these cases provided a more holistic understanding of these buildings’ performance than could have been achieved by either observational or more traditional questionnaire-based methods. Moreover, the whole-school approach, involving children in POE, provided researchers with highly contextualised information about how a school is used, how to improve the quality of school experiences (both socially and educationally) and how the school community is contributing to the building's energy performance. These POE methods also provided unique opportunities for children to examine the social and cultural factors impeding the adoption of energy-conscious and sustainable behaviours

A champion-driven pathway towards quality improvement in the medical management of osteoporotic fractures

The document attached has been archived with permission from the editor of the Medical Journal of Australia. An external link to the publisher’s copy is included.Tim Yu-Ting Lu, Jennifer A Pink, Lauren E Whitten, Catherine L Hill, Robert J Adams and Catherine Gib