Molluscs of the “Real Orto Botanico di Napoli”

The results of two years of research on the molluscs present in the Botanical Garden of Naples are reported and compared with the sole similar study published in 1875 and with other reports in the literature, the last of which published in 1930 by Boettger. As a general result, a noticeable decrease in the number of species present in the site was recorded. However, some species not reported before have also been observed, and namely Vallonia costata (O.F. Müller, 1774), Orcula dolium (Draparnaud, 1801) and Planorbarius corneus (Linnaeus, 1758), all recorded for the first time in Campania, and in addition Carychium minimum O.F. Müller, 1774, which appears to be well settled in the studied enclave; for this latter species the only previous indication was found in the bibliography for Campania (Bellini 1898). Finally, some limacid slugs, previously found and recorded only by Boettger (1930), have been found

Helicopter Pilots’ Tasks, Subjective Workload, and the Role of External Visual Cues During Shipboard Landing

Helicopter shipboard landing is a cognitively complex task that is challenging both for pilots and their crew. Effective communication, accurate reading of the flight instruments, as well as monitoring of the external environment are crucial for a successful landing. In particular, the final phases of landing are critical as they imply high workload situations in an unstable environment with restricted space. In the present qualitative study, we interviewed ten helicopter pilots from the Italian Navy using an applied cognitive task analysis approach. We aimed to obtain a detailed description of the landing procedure, and to identify relevant factors that affect pilots’ workload, performance, and safety. Based on the content analysis of the interviews, we have identified six distinct phases of approaching and landing on a ship deck and four categories of factors that may significantly affect pilots’ performance and safety of the landing procedure. Consistent with previous studies, our findings suggest that external visual cueing is vital for a successful landing, in particular during the last phases of landing. Therefore, based on the pilots’ statements, we provide suggestions for possible improvements of external visual cues that have the potential to reduce pilots’ workload and improve the overall safety of landing operations

Quantitative comparison between amyloid deposition detected by (99m)Tc-Diphosphonate imaging and myocardial deformation evaluated by strain echocardiography in transthyretin-related cardiac amyloidosis.

Methods and results 28 patients with transthyretin mutation and a group of 14 controls underwent echocardiography to quantify left ventricular (LV) dimensions and function, and global (G) longitudinal (L), radial (R) and circumferential (C) strain (S). 99mTc-3, 3-diphosphono-1, 2-propanodicarboxylic-acid-scintigraphy (99mTc-DPD) was used to quantify cardiac amyloidosis (CA). 99mTc-DPD revealed accumulation in 14 of 28 patients (CA-group) and no accumulation (no CA-group) in 14 patients. Cardiac accumulation was mild-moderate in 5 (Mild-Moderate CA-group) and severe in 9 patients (Severe CA-group). Severe CA-group showed higher values of LV septal thickness (LVST), posterior wall thickness and E/E' ratio than the no CA-group and the control group (adj. p<0.05). Ejection fraction was similar among groups (p=0.65). GLS was lower (p=<0.001) in severe CA-group (-12.2 ± 4.5) respect to no CA-group (-19.3 ± 3.0) and to the control group (-20.9 ± 2.5). On the contrary, GCS and GRS were lower (p=<0.05) in mild-moderate CA-group (-10.8 ± 4.1 and 9.5 ± 5.7, respectively) respect to the severe CA-group (-18.9 ± 5.1 and 23.9 ± 6.3 respectively), no CA-group (-19.2 ± 4.1 and 28.4 ± 10.2 respectively) and the control group (-23.9 ± 4.4 and 29.9 ± 8.7 respectively). A correlation was found between the scintigraphic heart retention (HR) index and LVST (r=0.72; p<0.001) and E/E' (r=0.46; p=0.03). An inverse tendency was observed between HR and GLS (r=−0.40; p=0.06)

Guidelines for the use and interpretation of diagnostic methods in adult food allergy

Food allergy has an increasing prevalence in the general population and in Italy concerns 8 % of people with allergies. The spectrum of its clinical manifestations ranges from mild symptoms up to potentially fatal anaphylactic shock. A number of patients can be diagnosed easily by the use of first- and second-level procedures (history, skin tests and allergen specific IgE). Patients with complex presentation, such as multiple sensitizations and pollen-food syndromes, frequently require a third-level approach including molecular diagnostics, which enables the design of a component-resolved sensitization profile for each patient. The use of such techniques involves specialists' and experts' skills on the issue to appropriately meet the diagnostic and therapeutic needs of patients. Particularly, educational programs for allergists on the use and interpretation of molecular diagnostics are needed

Usefulness of Combining Electrocardiographic and Echocardiographic Findings and Brain Natriuretic Peptide in Early Detection of Cardiac Amyloidosis in Subjects With Transthyretin Gene Mutation

Early noninvasive identification of cardiac amyloidosis (CA) is of growing clinical importance. Low voltage on electrocardiogram (ECG), increased left ventricular (LV) septal thickness (ST), and global longitudinal strain (GLS) on echocardiography, and elevated brain natriuretic peptides (BNP) are used as surrogates of CA. Thirty-five patients (50 ± 14 years, 22 women) underwent electrocardiography to analyze low-voltage QRS (\u3c15 \u3emV) pathologic Q waves, poor R-wave progression, ST-T abnormalities, and left bundle branch block. An ECG was considered abnormal if at least one ECG alteration was present. Echocardiography was used to analyze LVST, E/E\u27, and GLS. All participants also had BNP blood testing. (99m)Tc-3,3-diphosphono-1,2 propanodicarboxylic acid scintigraphy assumed as a reference method showed CA in 18 patients (51%, CA group) and no accumulation in 17 patients (no CA group). In descending order of accuracy, LVST \u3e14 mm, E/E\u27 \u3e6.6, GLS129 pg/ml, and an overall abnormal ECG showed good capability to distinguish patients with and without CA. All these parameters were predictors of CA in univariate analysis, whereas low-voltage QRS showed the worst performance. LVST \u3e14 mm (p = 0.002) was the best independent predictor of CA, achieving sensitivity of 78% and accuracy of 89%. However, an LVST \u3e14 mm (p = 0.005) plus an abnormal ECG (p = 0.03) show together a greater sensitivity, equal to 89%, in identifying CA. An integrated evaluation of ECG and echocardiography is a sensitive and low-cost technical approach to identify CA in patients with transthyretin gene mutation