Disabled people and the Internet: experiences, barriers and opportunities

The UK government aims to make all its information and transactions available electronically by 2005. General use of the Internet also continues to grow. This report investigates the Internet's barriers and benefits for disabled people, and considers whether it acts as a means to reduce their social exclusion. The study surveys the views and experiences of disabled people, both Internet users and non-users. Topics covered include: what the Internet is used for; use of and difficulties with assistive devices (special equipment and adaptations needed by some disabled people in order to use computers); how people learn to use the Internet; views of website accessibility; advantages and disadvantages of Internet usage. It also explores participants' restrictions on using the Internet, and people's reasons for not using it. There has been little previous research in this area, but the authors review the existing literature. The report finds that many practical problems - such as the cost of training, finding appropriate assistive devices, website accessibility - all inhibit Internet opportunities for many disabled people

Subtleties in the quasi-classical calculation of Hawking radiation

he quasi-classical method of deriving Hawking radiation is investigated. In order to recover the original Hawking temperature one must take into account a previously ignored contribution coming from the temporal part of the action. This contribution plus a contribution coming from the spatial part of the action gives the correct temperature.Comment: 6 pages revtex. Honorable Mention in 2008 GRF essay contest, typos fixed, sign errors corrected. To be published in Special Issue of IJMP

New symmetry current for massive spin-3/2 fields

We present several new results which will be of value to theorists working with massive spin-3/2 vector-spinor fields as found, for example, in low and intermediate energy hadron physics and also linearized supergravity. The general lagrangian and propagator for a vector-spinor field in d-dimensions is given. It is shown that the observables of the theory are invariant under a novel continuous symmetry group which is also extended to an algebra. A new technique is developed for exploring the consequences of the symmetry and a previously unknown conserved vector current and charge are found. The current leads to new interactions involving spin-3/2 particles and may have important experimental consequences.Comment: 9 pages, references updated and minor change

The genetics of human ageing

This is the author accepted manuscript. The final version is available from Nature Research via the DOI in this recordThe past two centuries have witnessed an unprecedented rise in human life expectancy. Sustaining longer lives with reduced periods of disability will require an understanding of the underlying mechanisms of ageing, and genetics is a powerful tool for identifying these mechanisms. Large-scale genome-wide association studies have recently identified many loci that influence key human ageing traits, including lifespan. Multi-trait loci have been linked with several age-related diseases, suggesting shared ageing influences. Mutations that drive accelerated ageing in prototypical progeria syndromes in humans point to an important role for genome maintenance and stability. Together, these different strands of genetic research are highlighting pathways for the discovery of anti-ageing interventions that may be applicable in humans.University of ExeterUniversity of ConnecticutMedical Research Council (MRC)National Institute on Agin

Hereditary haemochromatosis: associations with morbidity and iron supplement use in 451,243 UK Biobank participants

This is the author accepted manuscript. The final version is available from BMJ Publishing Group via the DOI in this recordSociety for Social Medicine and Population Health and International Epidemiology Association European Congress Annual Scientific Meeting 2019, Hosted by the Society for Social Medicine & Population Health and International Epidemiology Association (IEA), School of Public Health, University College Cork, Cork, Ireland, 4–6 September 2019Medical Research Council (MRC

Do alcohol product labels stating lower strength verbal description, percentage alcohol‐by‐volume, or their combination affect wine consumption? A bar laboratory adaptive randomised controlled trial

A previous research study concluded that wine and beer labelled as lower in strength increase consumption compared with the same drinks labelled as regular strength. The label included both a verbal and numerical descriptor of strength. The present study aimed to estimate the effect of each of these label components. Adaptive, parallel group randomised controlled trial, comprising an internal pilot sample (N = 90) and a confirmatory sample (N = 57). University bar laboratory in London UK. One-hundred and forty-seven weekly wine drinkers were sampled from a nationally representative English panel. Participants were randomised to one of three groups to taste test wine in a bar-laboratory, varying only in the label displayed: (i) verbal descriptor only (Super Low); (ii) numerical descriptor only (4%ABV); and (iii) verbal descriptor and numerical descriptor combined (Super Low 4%ABV) [each group n = 49]. The primary outcome was total volume (ml) of wine consumed. Participants randomised to the numerical descriptor label group (4%ABV: M = 155.12ml, B = 20.30, 95% CI = 3.92, 36.69, p-value = 0.016) and combined verbal and numerical descriptor label group (Super Low 4%ABV: M = 154.59ml, B = 20.68, 95%CI = 4.32, 37.04, p-value = 0.014) drank significantly greater amounts than those randomised to the verbal descriptor label group (Super Low: M = 125.65ml). This bar laboratory study estimated that a greater quantity of 'lower' strength wine was consumed when the label included a numerical strength descriptor compared with a verbal only strength descriptor. [Abstract copyright: This article is protected by copyright. All rights reserved.