Technical Support for Geopressured Geothermal Well Activities in Louisiana Annual Report

The rationale previously developed and utilized in interpreting various databases were outlined in the DOE final report titled "Technical Support for Geopressured-Geothermal Well Activities in Louisiana" (August 31, 1981), authored by Fred M. Wrighton, Don G. Bebout, Dale R. Carver, Charles G. Groat, and Adrain E. Johnson, Jr., under Contract No. DE-AS05-78ET27160. Due to the importance of the concepts presented in the previous report for developing an assessment evaluation program, much of the text and illustrations have been repeated for the convenience of the reader. However, the assessment techniques and calculations presented in this report are new. Estimates of the in-place methane resource in the geopressured zone of the U.S. Gulf Coast have varied widely, ranging from less than 1000 trillion cubic feet (TCF) to 49,000 TCF. The most recent assessment for onshore Texas, conducted by Gregory, Dodge, Posey, and Morton in 1981, estimated a total of 690 TCF. Well logs from deep oil and gas wells served as the primary data source for all assessment studies, although the interpretation of these logs varied significantly. In this study focusing on Louisiana, the methods and results were found to compare favorably with those of Gregory and others for Texas. The assessment included the Wilcox, Frio, and Miocene formations. Constructing regional cross-sections across the south Louisiana Gulf Coast was a prime objective to aid in assessing the total solution-methane resource in place. These cross-sections provided point sources of information from key wells and offered insights into the significance of each well through logical correlations with others on the section. Additionally, detailed studies of smaller areas conducted at LSU and other institutions throughout the Gulf Coast were considered, with data from these studies also contributing to the assessment. The total area under consideration in south Louisiana exceeds 18,000 square miles, with geopressured formations including the Wilcox (1692 square miles), Frio (5200 square miles), and Miocene. Parameters considered in this assessment included pressure, sandstone volume, porosity, temperature, and salinity.Bureau of Economic Geolog

Fleas as parasites of the family Canidae

Historically, flea-borne diseases are among the most important medical diseases of humans. Plague and murine typhus are known for centuries while the last years brought some new flea-transmitted pathogens, like R. felis and Bartonella henselae. Dogs may play an essential or an accidental role in the natural transmission cycle of flea-borne pathogens. They support the growth of some of the pathogens or they serve as transport vehicles for infected fleas between their natural reservoirs and humans. More than 15 different flea species have been described in domestic dogs thus far. Several other species have been found to be associated with wild canids. Fleas found on dogs originate from rodents, birds, insectivores and from other Carnivora. Dogs therefore may serve as ideal bridging hosts for the introduction of flea-borne diseases from nature to home. In addition to their role as ectoparasites they cause nuisance for humans and animals and may be the cause for severe allergic reactions

A study protocol for the evaluation of occupational mutagenic/carcinogenic risks in subjects exposed to antineoplastic drugs: a multicentric project

<p>Abstract</p> <p>Background</p> <p>Some industrial hygiene studies have assessed occupational exposure to antineoplastic drugs; other epidemiological investigations have detected various toxicological effects in exposure groups labeled with the job title. In no research has the same population been studied both environmentally and epidemiologically. The protocol of the epidemiological study presented here uses an integrated environmental and biological monitoring approach. The aim is to assess in hospital nurses preparing and/or administering therapy to cancer patients the current level of occupational exposure to antineoplastic drugs, DNA and chromosome damage as cancer predictive effects, and the association between the two.</p> <p>Methods/Design</p> <p>About 80 healthy non-smoking female nurses, who job it is to prepare or handle antineoplastic drugs, and a reference group of about 80 healthy non-smoking female nurses not occupationally exposed to chemicals will be examined simultaneously in a cross-sectional study. All the workers will be recruited from five hospitals in northern and central Italy after their informed consent has been obtained.</p> <p>Evaluation of surface contamination and dermal exposure to antineoplastic drugs will be assessed by determining cyclophosphamide on selected surfaces (wipes) and on the exposed nurses' clothes (pads). The concentration of unmetabolized cyclophosphamide as a biomarker of internal dose will be measured in end-shift urine samples from exposed nurses.</p> <p>Biomarkers of effect and susceptibility will be assessed in exposed and unexposed nurses: urinary concentration of 8-hydroxy-2-deoxyguanosine; DNA damage detected using the single-cell microgel electrophoresis (comet) assay in peripheral white blood cells; micronuclei and chromosome aberrations in peripheral blood lymphocytes. Genetic polymorphisms for enzymes involved in metabolic detoxification (i.e. glutathione <it>S</it>-transferases) will also be analysed.</p> <p>Using standardized questionnaires, occupational exposure will be determined in exposed nurses only, whereas potential confounders (medicine consumption, lifestyle habits, diet and other non-occupational exposures) will be assessed in both groups of hospital workers.</p> <p>Statistical analysis will be performed to ascertain the association between occupational exposure to antineoplastic drugs and biomarkers of DNA and chromosome damage, after taking into account the effects of individual genetic susceptibility, and the presence of confounding exposures.</p> <p>Discussion</p> <p>The findings of the study will be useful in updating prevention procedures for handling antineoplastic drugs.</p

Technical support for geopressured-geothermal-well activities in Louisiana. Annual report for the period November 1, 1980 - October 31, 1981

Separate abstracts were prepared for seven subprojects in this report.(MHR

Towards a political geography of United Nations peacekeeping: Some considerations

10.1007/BF00813823GeoJournal342177-190GEOJ