MOTIM – An Industrial Application Using NOCs

High-speed networks used to interconnect computers advance at an extraordinary pace, driven by the evolution of several contributing technologies. Due to the ever-increasing complexity of designing parts and equipments for these networks, design complexity management makes scalability and reusability more important issues than performance, in most cases. This paper describes MOTIM, a scalable and reusable architecture enabling the implementation of Ethernet switches with low latency and high throughput. The architecture is built around a network-on-chip-based switch fabric, which guarantees scalability. The architecture has been validated by functional simulation and prototyped in FPGAs. The experimental results show that even under severe traffic conditions the architecture achieves packet transmission with low latencies. Categories and Subject Descriptor

Morphogenesis and Defoliation Frequency of Italian Ryegrass (\u3ci\u3eLolium multiflorum\u3c/i\u3e) and \u3ci\u3ePaspalum urvillei\u3c/i\u3e in Lowland under Three Levels of P and K

This trial was conducted to evaluate growth dynamics and defoliation frequency of Italian ryegrass (Lolium multiflorum) and Paspalum urvillei in a lowland area under three levels of P and K. Using randomization tests we observed that, in a general way, fertilizer treatments were not the determinant factors of leaf appearance and elongation rates for both species. Only the leaf appearance rate of Paspalum urvillei at 100 % of recommendation level and the elongation rate for Italian ryegrass, in the same treatment, was different. Probably other factors, like drainage, are contributing to these results. I. ryegrass phyllochron ranged from 57.3 to 72.6 degree-days. Paspalum urvillei presented higher grazing frequency in almost all evaluated periods, revealing a high preference by the grazing animals

Tetracyclines in COVID-19 patients quarantined at home: Literature evidence supporting real-world data from a multicenter observational study targeting inflammatory and infectious dermatoses

Tetracyclines (TetraC) are widely used in dermatology for both inflammatory and infectious dermatoses; recently both in vivo and in vitro studies started to suggest also a potential antiviral effect. During COVID-19 outbreak, several dermatological patients contracted SARS-CoV-2 experiencing only mild symptoms, but no protocol were approved. A multicenter prospective observational study that enrolled COVID-19 patients visited with teledermatology and undergoing TetraC was performed. About 38 adult outpatients (M/F: 20/18, age 42.6 years [21-67]) were enrolled. During the TetraC treatment, symptoms resolved in all patients within 10 days. Remarkably, ageusia and anosmia disappeared in the first week of TetraC treatment. TetraC seem a promising drug to treat COVID-19 outpatients with mild symptoms

Differences in osteoimmunological biomarkers predictive of psoriatic arthritis among a large Italian cohort of psoriatic patients

(1) Background: In literature it is reported that 20\u201330% of psoriatic patients evolve to psoriatic arthritis over time. Currently, no specific biochemical markers can either predict progression to psoriatic arthritis or response to therapies. This study aimed to identify osteoimmunological markers applicable to clinical practice, giving a quantitative tool for evaluating pathological status and, eventually, to provide prognostic support in diagnosis. (2) Methods: Soluble (serum) bone and cartilage markers were quantified in 50 patients with only psoriasis, 50 psoriatic patients with psoriatic arthritis, and 20 healthy controls by means of multiplex and enzyme-linked immunoassays. (3) Results: Differences in the concentrations of matrix metalloproteases (MMPs), tissue inhibitors of metalloproteinases (TIMPs), receptor activator of nuclear factor kappa-B-ligand (RANK-L), procollagen type I N propeptide (PINP), C-terminal telopeptide of type I collagen (CTx-I), dickkopf-related protein 1 (DKK1), and sclerostin (SOST) distinguished healthy controls from psoriasis and psoriatic arthritis patients. We found that MMP2, MMP12, MMP13, TIMP2, and TIMP4 distinguished psoriasis from psoriatic arthritis patients undergoing a systemic treatment, with a good diagnostic accuracy (Area under the ROC Curve (AUC) > 0.7). Then, chitinase-3-like protein 1 (CHI3L1) and MMP10 distinguished psoriasis from psoriatic arthritis not undergoing systemic therapy and, in the presence of onychopathy, MMP8 levels were higher in psoriasis than in psoriatic arthritis. However, in these latter cases, the diagnostic accuracy of the identified biomarkers was low (0.5 < AUC < 0.7). (4) Conclusions. By highlighting never exploited differences, the wide osteoimmunological biomarkers panel provides a novel clue to the development of diagnostic paths in psoriasis and psoriasis-associated arthropathic disease

AVENS - A Novel Flying Ad Hoc Network Simulator with Automatic Code Generation for Unmanned Aircraft System

The wireless communication has played a significant impact on our daily lives introducing simplicity and making life more comfortable. \ As a result of faster technological advances in electronics and communications, the development of different types of unmanned aerial vehicles (UAVs) has become possible. \ Recently, many efforts have been made to develop more efficient inter- and intra-vehicle communication protocols introducing new challenges, e. g. multiple-UAV communication and Flying Ad Hoc Networks (FANETs). \ However, most of the experiments using real prototypes or systems are not feasible due to the costs and risks involved. \ Thus, simulating network protocol behavior in FANET scenarios is increasingly required to evaluate the applicability of developed network protocols. \ Thereby, we have been developing AVENS, a hybrid aerial network simulation framework, which merges LARISSA Architectural Model, X-Plane Flight Simulator and OMNeT++ Discrete Event Simulator. \ In a proof-of-concept study, we highlighted its advantages. \ Using AVENS, we can advance in the state-of-the-art concerning performance evaluation of intelligent aerial vehicles and provide means to evaluate the development of protocols, codes and systems more accurately