Thunder and Powder: May They Never Meet! Lightning Conductors at the Esplanade Powder Magazine, Quebec City

Archaeological excavations carried out at the Esplanade powder magazine in Quebec City have revealed the remains of three successive lighting conductor systems. These 19th-century remains are closely examined in the light of contemporary literature and compared with the military instructions concerning the subject. Their presence highlights the efforts made by military engineers of the time to safeguard contents, buildings, and people from the hazards inherent to the storage of explosive materials in powder magazines

Perspectives sur l'utilisation des TI en éducation au Québec

Tiré de l'écran-titre (visionné le 27 juin 2017).Ce rapport identifie les tendances majeures dans le domaine de la technologie et des pratiques (l’infonuagique, les données, la mobilité et l’éducation ouverte), ainsi que les enjeux associés et les composantes d’un modèle d’écologie d’apprentissage

Adenovirus 5 and chimeric adenovirus 5/F35 employ distinct B-lymphocyte intracellular trafficking routes that are independent of their cognate cell surface receptor

AbstractGene transfer applications with adenovirus (Ad) type 5 are limited by its native tropism, hampering their use in several cell types. To address this limitation, several Ad vectors bearing chimeric fiber have been produced to take advantage of the different cellular receptors used by other subgroups of Ads. In this study, we have compared the transduction efficiency of Ad5 and the chimeric Ad5/F35 in primary human B lymphocytes and B-cell lines as a function of the developmental stage. We found that transduction efficiencies of the two Ads differ independently of their targeted cellular receptor but are related to the intracellular localization of the virus. In efficiently transduced cells, Ads were localized in early endosomes or cytosol, whereas in poorly transduced cells they were localized within late endosomes/lysosomes. Finally, we demonstrate that treatment of cells with phosphatase inhibitors known to redirect endocytosis towards caveolae, increased Ad5/F35 transduction efficiency

Influence of statin use on clinicopathological characteristics of localized prostate cancer and outcomes obtained after radical prostatectomy: a single center study

To assess the impact of statin use on biochemical recurrence (BCR) of prostate cancer after radical prostatectomy (RP)

Guide pédagogique du Portfolio D.E.S.S. en administration de l'éducation

Dans le contexte du DESS en administration de l’éducation, le portfolio est un outil d’apprentissage qui amène l’étudiant à vivre un processus réflexif supervisé et à organiser une collection de productions significatives s’accumulant progressivement à l’intérieur du déroulement des cours. Le guide pédagogique explique les choix qui ont donné lieu au Portfolio pour les étudiants. Le portfolio suppose une réflexion en deux temps, le premier en a priori et portant sur le profil de sortie, le glossaire, le guide de choix de cours et le choix des compétences à développer par l’étudiant selon les cours et le second, a posteriori, et portant essentiellement sur l’écart existant entre les intentions d’apprentissage exprimées au départ et le niveau atteint à la fin du programme.Document produit dans le cadre d'un projet CLI

Analog programming of CMOS-compatible Al2_2O3_3/TiO2-x_\textrm{2-x} memristor at 4.2 K after metal-insulator transition suppression by cryogenic reforming

The exploration of memristors' behavior at cryogenic temperatures has become crucial due to the growing interest in quantum computing and cryogenic electronics. In this context, our study focuses on the characterization at cryogenic temperatures (4.2 K) of TiO$_\textrm{2-x}$-based memristors fabricated with a CMOS-compatible etch-back process. We demonstrate a so-called cryogenic reforming (CR) technique performed at 4.2 K to overcome the well-known metal-insulator transition (MIT) which limits the analog behavior of memristors at low temperatures. This cryogenic reforming process was found to be reproducible and led to a durable suppression of the MIT. This process allowed to reduce by approximately 20% the voltages required to perform DC resistive switching at 4.2 K. Additionally, conduction mechanism studies of memristors before and after cryogenic reforming from 4.2 K to 300 K revealed different behaviors above 100 K, indicating a potential change in the conductive filament stoichiometry. The reformed devices exhibit a conductance level that is 50 times higher than ambient-formed memristor, and the conduction drop between 300 K and 4.2 K is 100 times smaller, indicating the effectiveness of the reforming process. More importantly, CR enables analog programming at 4.2 K with typical read voltages. Suppressing the MIT improved the analog switching dynamics of the memristor leading to approximately 250% larger on/off ratios during long-term depression (LTD)/long-term potentiation (LTP) resistance tuning. This enhancement opens up the possibility of using TiO$_{\textrm{2-x}}$-based memristors to be used as synapses in neuromorphic computing at cryogenic temperatures

Cartes conceptuelles du Glossaire

Ce guide pédagogique fait suite au Glossaire du DESS en administration de l'éducation. Il explique comment les mots du vocabulaire relié au travail des directions d'établissement scolaire et à leur formation peuvent être regroupés dans des cartes conceptuelles pour mieux en saisir la portée. Il explicite aussi la conception et la construction de cartes conceptuelles et présente des exemples issus de la concertation entre les formateurs

Innovating in Teaching Collaborative Practice with a Large Student Cohort at Université de Montréal

Université de Montréal implemented an interprofessional education (IPE) curriculum on collaborative practice in a large cohort of students (>1,100) from 10 health sciences and psychosocial sciences training programs. It is made up of three one-credit undergraduate courses (CSS1900, CSS2900, CSS3900) spanning the first 3 years of training. The course content and activities aim for development of the six competency domains identified by the Canadian Interprofessional Health Collaborative. This paper describes the IPE curriculum and highlights the features contributing to its success and originality. Among main success key factors were: administrative cooperation among participating faculties, educators eager to develop innovative approaches, extensive use of clinical situations conducive to knowledge and skill application, strong logistic support, close cooperation with health care delivery organizations, and partnership between clinicians and patients. A distinguishing feature of this IPE curriculum is the concept of partnership in care between the patient and caregivers. Patients’ representatives were involved in course planning, and patients were trained to become patients-as-trainers (PT) and cofacilitate interprofessional discussion workshops. They give feed- back to students regarding integration and application of the patient partnership concept from a patient’s point of view. Lire l'article/Read the article : http://openurl.ingenta.com/content?genre=article&issn=0090-7421&volume=42&issue=4&spage=97E&epage=106