A blast of mistakes: undiagnosed cervical ppondylolisthesis following a bomb explosion

Background: A case of spinal trauma had an unusual clinical course due to medical mistakes, from which we can learn some important lessons. Case Report: We report a case of spondylolisthesis following a bomb explosion, which went undiagnosed for a long time because of a series of mistakes that are highlighted in this article. What makes this case unique is that the spondylolisthesis developed during hospital stay, but the patient had no loss of mobility, strength, or sensitivity. Conclusions: This case shows that establishing the conditions of an organ or a body part upon admission to hospital may not be enough when a patient has suffered extensive and serious trauma, and that it is necessary to carry out more checkups over time, especially if there are new clues and symptoms

Delineating a new critical region for juvenile myoclonic epilepsy at the 22q11.2 chromosome

No abstract availabl

Multiple ectopic leiomyomas of the abdominal rectus muscles after gasless laparoscopic uterine myomectomy

To describe and analyze the first case of multiple ectopic leiomyomas of the abdominal rectus muscles in a patient who had undergone gasless laparoscopic uterine myomectomy (GLM) 10 years before

Single-incision laparoscopic adnexectomy in an obese patient with previous laparotomies

No case of single-incision laparoscopic surgery in obese patients who had previously undergone multiple midline vertical laparotomies has been described in the literature to date. Hence we report the first case of single-port laparoscopic salpingo-oophorectomy in an obese patient who was affected by a left adnexal mass and who had previously undergone 3 midline vertical laparotomies

The peripartum period influenced the serum macromineral profile in mares

Changes in metabolic requirements during pregnancy may produce nutritional imbalances predisposing mares to pathological conditions. Therefore, we aimed to examine changes in serum macrominerals during the peripartum period in mares. Fifteen pregnant mares (Group A) were monitored starting at the 263rd day of pregnancy until the 21st day after foaling. Seven non-pregnant and non-lactating mares were used as a control group (Group B). Group A was subjected to blood sampling within 24-12 h after parturition (P) and then 7, 14 and 21 days after foaling (C1, C2, C3 weeks, respectively). Group B was subjected to regular sampling throughout the study to ensure that seasonal changes had no significant effect on studied parameters. Serum samples were analysed for serum electrolytes including sodium (NaC), potassium (KC), calcium (CaCC), phosphorus (PC), chloride (Cl) and magnesium (MgCC). Two-way repeated measures of analysis of variance (ANOVA) was applied to evaluate significant effects of peripartum on electrolyte concentrations. Group A showed a decrease in Cl concentrations (P D 0:011) after foaling and lower PC concentrations (P D 0:015) compared to Group B throughout the study. The linear regression model showed an increase in NaC concentrations (P D 0:002) and a gradual decrease in serum CaCC (P D 0:001) during pregnancy. Because the most significant changes in serum electrolytes occurred within 2 weeks before and 2 weeks after foaling, monitoring serum electrolyte concentrations would indicate whether the mare needs further mineral supplementation at this stage. The significant changes in a mare's macromineral profile that we observed over the peripartum provide enhanced knowledge about mineral interrelations and their modifications during specific physiological conditions such as late pregnancy and early postpartum

Serum total proteins and related electrophoretic fractions in growing foals

Abstract. The aim of this study was to evaluate the changes of serum total proteins, albumin, α1-, α2-, β1-, β2 and γ-globulins in growing foals during the first month of life. Nine clinically healthy foals (five females and four males, mean body weight 39.00 ± 3.50 kg) were enrolled in the study. From each animal, blood samples were collected by jugular venipuncture every 3 days during the first month of life starting from the day of birth. Serum concentration of total proteins, albumin, α1, α2, β1, β2 and γ-globulins was assessed. One-way repeated measures analysis of variance (ANOVA), followed by Bonferroni post hoc comparison test, was used to determine statistically significant effect of the day of life on studied parameters. A statistically significant effect of the day of life on serum total proteins (P < 0.0001), albumin (P < 0.0001) and γ-globulins (P < 0.005) was observed during the first month of life. Our findings emphasize the importance of establishing different reference intervals for serum electrophoretic protein profiles in growing foals based on their physiological status. This study provides useful information that could help clinicians to better interpret clinical data and diagnose equine neonatal disease

Randomized comparison of total laparoscopic, laparoscopically assisted vaginal and vaginal hysterectomies for myomatous uteri

To compare the operative data and early postoperative outcomes of total laparoscopic hysterectomy (TLH), laparoscopically assisted vaginal hysterectomy (LAVH) and vaginal hysterectomy (VH). One hundred and eight women requiring hysterectomy for enlarged myomatous uterus were randomly allocated into three treatment arms: TLH (n = 36); LAVH (n = 36); VH (n = 36). Randomization procedure was based on a computer-generated list. The primary outcome was the discharge time comparison. The secondary outcomes were operating time, blood loss, paralytic ileus time, intraoperative complications, postoperative pain, and early postoperative complications. The mean discharge time was shorter after VH than after LAVH and TLH (P = 0.001). Operating time significantly influenced the discharge time, considered as a dependent variable in general linear model analysis (P = 0.006). In contrast, blood loss did not influence the discharge time (P = 0.55).The mean operating time was significantly shorter in VH than in TLH and LAVH groups (P = 0.000).The intraoperative blood loss was greater during LAVH than during TLH and VH (P = 0.000).Paralytic ileus time was shorter after VH than after TLH and LAVH (P = 0.000). No intraoperative complications or conversion to laparotomy occurred. VH was the faster operative technique with smaller blood loss and shorter discharge time compared with the others two techniques. So, VH should be considered the preferred approach in patients with enlarged myomatous uteri. When VH is not feasible or salpingo-oophorectomy is required, LAVH or TLH should be considered as valid alternatives. It is necessary to continue prospective comparative studies between the various surgical options to identify the best approach for hysterectomy in each single woman

Serum thyroid hormone evaluation during transition periods in dairy cows

Abstract. Thirty-five multiparous Holstein dairy cows were selected from a high-producing dairy farm in northeastern Italy: 16 in second lactation (L2), 10 in third lactation (L3) and 9 in fourth lactation (L4). Blood sampling was carried out 7 ± 5 days before calving (Pre/C) and 7 ± 5 days after calving (Post/C). Serum triiodothyronine (T3), thyroxine (T4) and a thyroid-stimulating hormone (TSH) were assessed. Two-way analysis of variance (ANOVA) showed statistically significant effects of class (L2, L3, L4) and of period (Pre/C, Post/C) on the parameters studied (T3, T4, TSH). In particular, Bonferroni's multiple comparison test showed lower values in post-calving than in the pre-calving in L2 and L3 for TSH; lower values in post-calving than in the pre-calving in L2 for T3; and lower values in post-calving than in the pre-calving in L2, L3 and L4 for T4. Our results improve the knowledge of endocrine and metabolic changes occurring in dairy cows during transition periods and may be useful to supply a new strategy for the improvement of dairy cow farm management and reproductive performance