Efficient Wage Subsidies in Private Firms and Deadweight Spending

This paper links the old literature on employment subsidies with the current theories of contract and regulation. One important source of inefficiency of employment subsidies is deadweight spending. This refers to the cases in which private firms receive a subsidy for employment creation that would have been reached without this financial support. We identify the asymmetry of information between the regulator and the private firm as the source of this deadweight spending. The private firm knows its hiring capability while the government does not. We then derive the optimal incentive contracts for the government. In these contracts deadweight spending is reduced to the information rent to private firms. We derive conditions for which this deadweight spending is zero.Contract-Theory; Principal-Agent; Economic-Policy; Employment-Subsidy; Cost-Benefit-Analysis

Decomposition of Triebel-Lizorkin and Besov spaces in the context of Laguerre expansions

A pair of dual frames with almost exponentially localized elements (needlets) are constructed on \RR_+^d based on Laguerre functions. It is shown that the Triebel-Lizorkin and Besov spaces induced by Laguerre expansions can be characterized in terms of respective sequence spaces that involve the needlet coefficients.Comment: 42 page

Subsampling needlet coefficients on the sphere

In a recent paper, we analyzed the properties of a new kind of spherical wavelets (called needlets) for statistical inference procedures on spherical random fields; the investigation was mainly motivated by applications to cosmological data. In the present work, we exploit the asymptotic uncorrelation of random needlet coefficients at fixed angular distances to construct subsampling statistics evaluated on Voronoi cells on the sphere. We illustrate how such statistics can be used for isotropy tests and for bootstrap estimation of nuisance parameters, even when a single realization of the spherical random field is observed. The asymptotic theory is developed in detail in the high resolution sense.Comment: Published in at http://dx.doi.org/10.3150/08-BEJ164 the Bernoulli (http://isi.cbs.nl/bernoulli/) by the International Statistical Institute/Bernoulli Society (http://isi.cbs.nl/BS/bshome.htm

Asymptotics for spherical needlets

We investigate invariant random fields on the sphere using a new type of spherical wavelets, called needlets. These are compactly supported in frequency and enjoy excellent localization properties in real space, with quasi-exponentially decaying tails. We show that, for random fields on the sphere, the needlet coefficients are asymptotically uncorrelated for any fixed angular distance. This property is used to derive CLT and functional CLT convergence results for polynomial functionals of the needlet coefficients: here the asymptotic theory is considered in the high-frequency sense. Our proposals emerge from strong empirical motivations, especially in connection with the analysis of cosmological data sets.Comment: Published in at http://dx.doi.org/10.1214/08-AOS601 the Annals of Statistics (http://www.imstat.org/aos/) by the Institute of Mathematical Statistics (http://www.imstat.org

Optimal detection of changepoints with a linear computational cost

We consider the problem of detecting multiple changepoints in large data sets. Our focus is on applications where the number of changepoints will increase as we collect more data: for example in genetics as we analyse larger regions of the genome, or in finance as we observe time-series over longer periods. We consider the common approach of detecting changepoints through minimising a cost function over possible numbers and locations of changepoints. This includes several established procedures for detecting changing points, such as penalised likelihood and minimum description length. We introduce a new method for finding the minimum of such cost functions and hence the optimal number and location of changepoints that has a computational cost which, under mild conditions, is linear in the number of observations. This compares favourably with existing methods for the same problem whose computational cost can be quadratic or even cubic. In simulation studies we show that our new method can be orders of magnitude faster than these alternative exact methods. We also compare with the Binary Segmentation algorithm for identifying changepoints, showing that the exactness of our approach can lead to substantial improvements in the accuracy of the inferred segmentation of the data.Comment: 25 pages, 4 figures, To appear in Journal of the American Statistical Associatio

Characterization of a dense aperture array for radio astronomy

EMBRACE@Nancay is a prototype instrument consisting of an array of 4608 densely packed antenna elements creating a fully sampled, unblocked aperture. This technology is proposed for the Square Kilometre Array and has the potential of providing an extremely large field of view making it the ideal survey instrument. We describe the system,calibration procedures, and results from the prototype.Comment: 17 pages, accepted for publication in A&

Preventing pain on injection of propofol: A comparison between lignocaine pre-treatment and lignocaine added to propofol

Publisher's copy made available with the permission of the publisherA randomized double-blind study compared two methods of preventing the pain from injection of propofol, lignocaine pre-treatment followed by propofol and lignocaine added to propofol. One hundred patients received a 4 ml solution intravenously with a venous tourniquet for 1 minute, followed by propofol mixed with 2 ml of solution. Patients were divided into two treatment groups of 50 patients each: 4 ml 1% lignocaine pre-treatment followed by propofol and 2 ml saline, or 4 ml saline followed by propofol and 2 ml 2% lignocaine. Pain was assessed with a 100 mm visual analogue scale after induction and in recovery. The incidence of injection pain was 8% in the propofol mixed with lignocaine group, and 28% in the lignocaine pre-treatment group. This difference is statistically significant (P=0.017). For those patients who had pain, the mean pain score was 26.5 on induction for the propofol with lignocaine group (n=4), while the mean score was 44.4 for the pre-treatment group (n=13). The difference was not statistically significant (P=0.25). None of the propofol mixed with lignocaine group recalled pain, while 13 of the pre-treatment group did so. Lignocaine pre-treatment does not improve the immediate or the recalled comfort of patients during propofol induction when compared to lignocaine added to propofol. It is recommended that lignocaine should be added to propofol for induction rather than given before induction.P. Lee, W. J. Russellhttp://www.aaic.net.au/Article.asp?D=200339

Constitutive association of BRCA1 and c-Abl and its ATM-dependent disruption after irradiation

BRCA1 plays an important role in mechanisms of response to double-strand breaks, participating in genome surveillance, DNA repair, and cell cycle checkpoint arrests. Here, we identify a constitutive BRCA1-c-Abl complex and provide evidence for a direct interaction between the PXXP motif in the C terminus of BRCA1 and the SH3 domain of c-Abl. Following exposure to ionizing radiation (IR), the BRCA1-c-Abl complex is disrupted in an ATM-dependent manner, which correlates temporally with ATM-dependent phosphorylation of BRCA1 and ATM-dependent enhancement of the tyrosine kinase activity of c-Abl. The BRCA1-c-Abl interaction is affected by radiation-induced modification to both BRCA1 and c-Abl. We show that the C terminus of BRCA1 is phosphorylated by c-Abl in vitro. In vivo, BRCA1 is phosphorylated at tyrosine residues in an ATM-dependent, radiation-dependent manner. Tyrosine phosphorylation of BRCA1, however, is not required for the disruption of the BRCA1-c-Abl complex. BRCA1-mutated cells exhibit constitutively high c-Abl kinase activity that is not further increased on exposure to IR. We suggest a model in which BRCA1 acts in concert with ATM to regulate c-Abl tyrosine kinase activity

Water Vapour Effects in Mass Measurement

Water vapour inside the mass comparator enclosure is a critical parameter. In fact, fluctuations of this parameter during mass weighing can lead to errors in the determination of an unknown mass. To control that, a proposal method is given and tested. Preliminary results of our observation of water vapour sorption and desorption processes from walls and mass standard are reported