Taking up the cudgels against gay rights? Trends and trajectories in African Christian theologies on homosexuality

Against the background of the HIV epidemic and the intense public controversy on homosexuality in African societies, this article investigates the discourses of academic African Christian theologians on homosexuality. Distinguishing some major strands in African theology, that is, inculturation, liberation, women’s and reconstruction theology, the article examines how the central concepts of culture, liberation, justice, and human rights function in these discourses. On the basis of a qualitative analysis of a large number of publications, the article shows that stances of African theologians are varying from silence and rejection to acceptance. Although many African theologians have taken up the cudgels against gay rights, some “dissident voices” break the taboo and develop more inclusive concepts of African identity and African Christianity

Effects of Compost Manure on Soil Microbial Respiration, Plant-Available-Water, Peanut (Arachis hypogaea L.) Yield and Pre-Harvest Aflatoxin Contamination

Peanut production in Zambia is often characterized by low yields and high aflatoxin incidence in harvested kernels. Soil amendments such as farmyard manure have shown potential to increase yields and reduce pre-harvest aflatoxin incidence. The aim of the current study was to evaluate the effects of composted cattle manure on soil properties that relate to yield and pre-harvest aflatoxin contamination of peanut kernels. Research evaluated the effects of composted cattle manure on soil respiration, plant-available water (PAW), peanut yield and pre-harvest aflatoxin contamination in a field experiment conducted in two successive rain-fed cropping seasons starting in December, 2015 and ending in April 2017, in Chongwe District, Zambia. Six (6) levels of compost were incorporated into the top 10 cm of the soil at rates of 0, 4.5, 12.0, 19.5, 27.0, and 34.5 metric tons/ha 1 wk before planting. There was a strong positive relationship between levels of compost and soil microbial respiration (R2=0.84) and PAW (R2=0.86). Secondly, compost manure was associated with increases in pod (R2=0.65) and kernel (R2=0.61) yield. The kernel yield potential of the planted cultivar was achieved at the rate of 12 metric tons per ha. Thirdly, there was a reduction in total aflatoxin levels with increasing levels of compost (R2=0.85). The improvement in peanut yield and the decrease in aflatoxin concentrations in kernels can be attributed to the improvement in soil moisture retention capacity and soil microbial activity arising from manure amendments. This study demonstrated the potential of compost manure to increase soil microbial activity, PAW, peanut yield and minimize aflatoxin contamination at field level

Culturally Adapted Interventions in Mental Health: Global Position Statement

The preponderance of western psychological concepts are often relied upon to conceptualise health-related phenomena. It is hardly surprising therefore that despite the availability of a number of interventions, studies have concluded that outcomes for minority cultural groups are not as good as for Caucasian people (western Europe and North America) in many high and middle income countries (HMIC). The evidence base of most psychosocial interventions is yet to be established in Low and Middle Income Countries (LMICs). There has been a propensity in some quarters to view low and middle income countries as passive beneficiaries of mental health knowledge, rather than as contributors or partners in knowledge production and development. A move towards a more equal bilateral relationship is called for, which should lead to better service provision. This Position Statement aims to highlight the current position and need for culturally adapted interventions. It is a global call for action to achieve a standardised mechanism to achieve parity of access and outcomes across all cultural groups regardless of country of residence

Pan-GWAS of Streptococcus agalactiae highlights lineage-specific genes associated with virulence and niche adaptation

Streptococcus agalactiae (Group B streptococcus, GBS) is a coloniser of the gastrointestinal and urogenital tracts, and an opportunistic pathogen of infants and adults. The worldwide population of GBS is characterised by Clonal Complexes (CCs) with different invasive potentials. CC17 for example, is a hypervirulent lineage commonly associated with neonatal sepsis and meningitis, while CC1 is less invasive in neonates and more commonly causes invasive disease in adults with co-morbidities. The genetic basis of GBS virulence and to what extent different CCs have adapted to different host environments remain uncertain. We have therefore applied a pan-genome wide association study approach to 1988 GBS strains isolated from different hosts and countries. Our analysis identified 279 CC-specific genes associated with virulence, disease, metabolism and regulation of cellular mechanisms that may explain the differential virulence potential of particular CCs. In CC17 and CC23 for example, we have identified genes encoding for pilus, quorum sensing proteins, and proteins for the uptake of ions and micronutrients which are absent in less invasive lineages. Moreover, in CC17, carriage and disease strains were distinguished by the allelic variants of 21 of these CC-specific genes. Together our data highlight the lineage-specific basis of GBS niche adaptation and virulence, and suggest that human-associated GBS CCs have largely evolved in animal hosts before crossing to the humans and then spreading clonally

Effects of age, gender and soil-transmitted helminth infection on prevalence of Plasmodium infection among population living in bata district, equatorial Guinea

INTRODUCTION: Malaria and soil-transmitted helminth (STH) co-infection is an important parasitic infection affecting populations in co-endemic countries including Equatorial Guinea. To date, the health impact of STH and malaria co-infection is inconclusive. The current study aimed to report the malaria and STH infection epidemiology in the continental region of Equatorial Guinea. METHODS: We performed a cross-sectional study between October 2020 and January 2021 in the Bata district of Equatorial Guinea. Participants aged 1-9 years, 10-17 years and above 18 were recruited. Fresh venous blood was collected for malaria testing via mRDTs and light microscopy. Stool specimens were collected, and the Kato-Katz technique was used to detect the presence of Ascaris lumbricoides, Trichuris trichiura, hookworm spp. and intestinal Schistosoma eggs. RESULTS: A total of 402 participants were included in this study. An amount of 44.3% of them lived in urban areas, and only 51.9% of them reported having bed nets. Malaria infections were detected in 34.8% of the participants, while 50% of malaria infections were reported in children aged 10-17 years. Females had a lower prevalence of malaria (28.8%) compared with males (41.7%). Children of 1-9 years carried more gametocytes compared with other age groups. An amount of 49.3% of the participants infected with T. trichiura had malaria parasites compared with those infected with A. lumbricoides (39.6%) or both (46.8%). CONCLUSIONS: The overlapping problem of STH and malaria is neglected in Bata. The current study forces the government and other stakeholders involved in the fight against malaria and STH to consider a combined control program strategy for both parasitic infections in Equatorial Guinea

Building financial management capacity for community ownership of development initiatives in rural Zambia

Background: Building financial management capacity is increasingly important in low- and middle-income countries to help communities take ownership of development activities. Yet, many community members lack financial knowledge and skills. Methods: As part of a larger health intervention, we designed and conducted financial management training for 83 members from 10 community groups in rural Zambia. Change scores between pre- and post-tests on financial knowledge were calculated and multivariate linear regression models run. Qualitative feedback was elicited. Results: The training significantly improved knowledge of financial concepts. Participants with some or more than some secondary education had greater improvements in knowledge (by 1.8 and 2.9 points out of 10 respectively; p=0.003 and p\u3c0.001). Participants appreciated exercises to contextualize financial concepts within daily life, and liked opportunities to learn from peers in small groups. Language barriers were a particular challenge. Conclusion: Financial management training may contribute to the sustainability of community-managed interventions but needs to be tailored to the background and education level of the participants. Training should relate financial concept to more tangible applications and provide time for active learning. This training approach could be used in similar settings to improve community oversight of resources intended to strengthen developmental initiatives

Intracellular survival of Streptococcus pneumoniae in human alveolar macrophages is augmented with HIV infection

People Living with HIV (PLHIV) are at an increased risk of pneumococcal pneumonia than HIV-uninfected adults, but the reasons for this are still not well understood. We investigated whether alveolar macrophages (AM) mediated control of pneumococcal infection is impaired in PLHIV compared to HIV-uninfected adults. We assessed anti-bactericidal activity against Streptococcus pneumoniae of primary human AM obtained from PLHIV and HIV-uninfected adults. We found that pneumococcus survived intracellularly in AMs at least 24 hours post ex vivo infection, and this was more frequent in PLHIV than HIV-uninfected adults. Corroborating these findings, in vivo evidence showed that PLHIV had a higher propensity for harboring S. pneumoniae within their AMs than HIV-uninfected adults. Moreover, bacterial intracellular survival in AMs was associated with extracellular propagation of pneumococcal infection. Our data suggest that failure of AMs to eliminate S. pneumoniae intracellularly could contribute to the increased risk of pneumococcal pneumonia in PLHIV

Effects of biochar and gypsum soil amendments on groundnut (Arachis hypogaea L.) dry matter yield and selected soil properties under water stress

The effects of amending soil with gypsum and biochar on groundnut chlorophyll concentration, water use efficiency (WUE), biomass yield and selected soil properties were investigated under water stress. Gypsum (CaSO4.2H2O) was applied at 0 and 200 kg/ha, groundnut shell biochar at 1, 2 and 4% w/w of soil, and water at 100, 70 and 40% of daily plant water requirement (PWR) as main, sub and sub-sub plots, respectively, in a split-split-plot design. Biochar neutralized the acid soil, significantly raising soil pH from 5 to 7.15 and increasing cation exchange capacity by 75%. Biochar amended at 1 and 2%, increased groundnut dry matter yield by 28%. The optimum biochar application rate for dry matter yield was 1.4% w/w. Biochar application at 4% and irrigation at 40% of PWR reduced the WUE by 45 and 50%, respectively. Chlorophyll concentration index was highest at 40% of PWR. The results suggest that biochar has potential to raise soil pH, increase moisture retention and improve crop performance. Applying water at 100% PWR can increase groundnut dry matter yields, while higher gypsum application rates may be required to affect crop performance

Hydrogeology and Groundwater Quality Atlas of Malawi : Water Resource Area 11: The Lake Chiuta Catchment

Groundwater in Water Resource Area 11 is interpreted within the same context as presented in the Hydrogeology and Water Quality Atlas Bulletin publication. A general description of the Hydrogeology of Malawi and its various units is provided here to remind the reader of the complexity of groundwater in Malawi and its nomenclature. The various basement geologic units have variable mineralogy, chemistry, and structural history that may be locally important for water quality parameters such as Fluoride, Arsenic and geochemical evolution. Therefore, translation of geologic units to potential hydrostratigraphic units was based on the 1:250,000-scale Geological Map of Malawi compiled by the Geological Survey Department of Malawi (Canon, 1978). Geological units were grouped into three main aquifer groups for simplicity