41 research outputs found

    The Search for Voice: Ideology and Perspective in the Black Community

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    During the last seven years, there has been a significant shift to the right in the ideological perspectives of Amencan political institutions and behavior. Despite some in consistencies, the direction is clear. The term “moderate” has acquired a conservative meaning, and liberals have been split into neo-liberal and neo-conservative camps. At this moment American society is informally declaring that it is not committed to achieving the goal ofequal outcomes long espoused by a mainly liberal national political and institutional system. The shift to the right is working changes on traditional black ideological perspectives, both among blacks and between black and white groups. The voices that in the past spoke for black interests, whether they came from black or white groups, no longer effectively present a clear or compelling vision of how we progress towards a just society. The lack of a coherent progressive ideology or voice is evident among blacks and whites. There is division and a lack of momentum. One result is a schism in the black community that has resulted in a loss of influence upon national policy. Blacks must articulate a new vision, must formulate new and progressive approaches that respond to the current social and political realities

    Issues Facing Boston: 1984, Housing

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    The housing problem in Boston is one issue facing the new council which offers both opportunity and complexity. In a city where 70 percent of the households are tenants, where incomes are low and housing expensive, and where major demographic and economic changes are taking place, easy answers are not available. But housing, unlike other issues, is a matter over which the city has some leverage so that progress will be noted and appreciated by an increasingly attentive electorate. In recent years, the city has not faced the challenge of greater local discretion in housing policy (made available by the abdication of the federal government), addressed the worsening condition in the stock, or offered solutions to problems of affordability. As a result your tenure with the council begins not in the mode of fine-tuning a reasonably good machinery, but at a point when the situation requires developing from scratch a city housing policy and the machinery to implement it

    The Search for Voice: Ideology and Perspective in the Black Community

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    During the last seven years there has been a significant shift to the right in the ideological perspectives of American political institutions and behavior. Despite some inconsistencies, the direction is clear. The term moderate has acquired a conservative meaning, and liberals have been split into neo-liberal and neoconservative camps. At this moment American society is informally declaring that it is not committed to achieving the goal of equal outcomes long espoused by a mainly liberal national political and institutional system. The shift to the right is working changes on traditional black ideological perspectives, both among blacks and between black and white groups. The voices that in the past spoke for black interests, whether they came from black or white groups, no longer effectively present a clear or compelling vision for how we progress towards a just society. The lack of a coherent progressive ideology or voice is evident among blacks and whites. There is division and a lack of momentum. One result is a schism in the black community that has resulted in a loss of influence upon national policy. Blacks must articulate a new vision, must formulate new and progressive approaches that respond to the current social and political realities

    The process of black suburbanization.

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    Thesis. 1975. Ph.D. cn--Massachusetts Institute of Technology. Dept. of Urban Studies and Planning.Bibliography: leaves 481-505.Ph.D.c

    The roles of age at puberty and energy restriction |in sow reproductive longevity: a genomic perspective

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    Approximately 50% of sows are culled annually with more than one-third due to poor fertility. Our research demonstrated that age at puberty is an early pre-breeding indicator of reproductive longevity. Age at puberty can be measured early in life, has a moderate heritability, and is negatively correlated with lifetime number of parities. Detection of age at puberty is tedious and time consuming and is therefore not collected by the industry, which limits genetic progress. Genomic prediction is a viable approach to preselect gilts that will express puberty early and have superior reproductive longevity. The hypothesis that genetic variants explaining differences in age at puberty also explain differences in sow reproductive longevity was tested. Phenotypes, genotypes, and tissues from the UNL resource population (n \u3e 1700) were used in genome-wide association analyses, genome, and RNA sequencing to uncover functional polymorphisms that could explain variation in puberty and reproductive longevity. A BeadArray including 56,424 SNP explained 25.2% of the phenotypic variation in age at puberty in a training set (n = 820). Evaluation of major windows and SNPs of subsequent batches of similar genetics (n = 412) showed that if all SNPs located in the major 1-Mb windows were tested, they explained a substantial amount of phenotypic variation (12.3 to 36.8%). Due to differences in linkage disequilibrium status, the most informative SNP from these windows explained a lower proportion of the variation (6.5 to 23.7%). To improve genomic predictive ability, the limited capability of BeadArray was enhanced by potential functional variants uncovered by genome sequencing of selected sires (n = 20; \u3e20X). There were 11.2 mil. SNPs and 2.9 mil. indels discovered across sires and reference genomes. The role of gene expression differences in explaining phenotypic variation in age at puberty was investigated by RNA sequencing of the hypothalamic arcuate nucleus (ARC) in gilts (n = 37) with different pubertal statuses. Seventy genes, including genes involved in reproductive processes, were differentially expressed between gilts with early and late puberty status (Padj \u3c 0.1). Dietary restriction of energy 3 mo before breeding delayed puberty by 7 d but improved the potential of a sow producing up to three parities (P \u3c 0.05). Energy restriction was associated with differential expression in 42 genes in the ARC, including genes involved in energy metabolism. This integrated genomic information will be evaluated in commercial populations to improve the reproductive potential of sows through genomic selection. This project is supported by AFRI Competitive grant no. 2013-68004-20370 from the USDA-NIFA. USDA is an equal opportunity provider and employer

    The initiation of simulation training at a large community hospital

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    OBJECTIVE: Since the 1990’s, simulation has been used to maintain task-oriented and behavioral skills in obstetrics and gynecology. Data on its effectiveness is still limited. The purpose of this study is to describe our experience in implementing simulation exercises at a large, private hospital. STUDY DESIGN: After reviewing the malpractice claims and maternal mortality impact of shoulder dystocia and postpartum hemorrhage, and the potential for a positive impact on patient safety through simulation training, shoulder dystocia and postpartum hemorrhage were selected as the initial focus of a new simulation training program for attending obstetrical physicians at a large, private, urban hospital. Upon obtaining approval from the institution, the Simulation Working Group developed an obstetrical simulation program emphasizing the management of shoulder dystocia and postpartum hemorrhage. Physicians who participate in deliveries at the institution were required to review a web-based educational program prior to the simulation exercise. Pre and post test questions were developed to assess the effectiveness of the information provided. The data was analyzed using Chi-Square testing with a p-value o

    The Impact of Advocacy Organizations on Low-Income Housing Policy in U.S. Cities

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    Financial support for affordable housing competes with many other municipal priorities. This work seeks to explain the variation in support for affordable housing among U.S. cities with populations of 100,000 or more. Using multivariate statistical analysis, this research investigates political explanations for the level of city expenditures on housing and community with a particular interest in the influence of housing advocacy organizations (AOs). Data for the model were gathered from secondary sources, including the U.S. Census and the National Center for Charitable Statistics. Among other results, the analysis indicates that, on average, the political maturity of AOs has a statistically significant, positive effect on local housing and community development expenditures

    Effects of antiplatelet therapy on stroke risk by brain imaging features of intracerebral haemorrhage and cerebral small vessel diseases: subgroup analyses of the RESTART randomised, open-label trial

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    Background Findings from the RESTART trial suggest that starting antiplatelet therapy might reduce the risk of recurrent symptomatic intracerebral haemorrhage compared with avoiding antiplatelet therapy. Brain imaging features of intracerebral haemorrhage and cerebral small vessel diseases (such as cerebral microbleeds) are associated with greater risks of recurrent intracerebral haemorrhage. We did subgroup analyses of the RESTART trial to explore whether these brain imaging features modify the effects of antiplatelet therapy

    Virological failure and development of new resistance mutations according to CD4 count at combination antiretroviral therapy initiation

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    Objectives: No randomized controlled trials have yet reported an individual patient benefit of initiating combination antiretroviral therapy (cART) at CD4 counts > 350 cells/μL. It is hypothesized that earlier initiation of cART in asymptomatic and otherwise healthy individuals may lead to poorer adherence and subsequently higher rates of resistance development. Methods: In a large cohort of HIV-positive individuals, we investigated the emergence of new resistance mutations upon virological treatment failure according to the CD4 count at the initiation of cART. Results: Of 7918 included individuals, 6514 (82.3%), 996 (12.6%) and 408 (5.2%) started cART with a CD4 count ≤ 350, 351-499 and ≥ 500 cells/μL, respectively. Virological rebound occurred while on cART in 488 (7.5%), 46 (4.6%) and 30 (7.4%) with a baseline CD4 count ≤ 350, 351-499 and ≥ 500 cells/μL, respectively. Only four (13.0%) individuals with a baseline CD4 count > 350 cells/μL in receipt of a resistance test at viral load rebound were found to have developed new resistance mutations. This compared to 107 (41.2%) of those with virological failure who had initiated cART with a CD4 count < 350 cells/μL. Conclusions: We found no evidence of increased rates of resistance development when cART was initiated at CD4 counts above 350 cells/μL. HIV Medicin
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