193 research outputs found
Content Delivery Latency of Caching Strategies for Information-Centric IoT
In-network caching is a central aspect of Information-Centric Networking
(ICN). It enables the rapid distribution of content across the network,
alleviating strain on content producers and reducing content delivery
latencies. ICN has emerged as a promising candidate for use in the Internet of
Things (IoT). However, IoT devices operate under severe constraints, most
notably limited memory. This means that nodes cannot indiscriminately cache all
content; instead, there is a need for a caching strategy that decides what
content to cache. Furthermore, many applications in the IoT space are
timesensitive; therefore, finding a caching strategy that minimises the latency
between content request and delivery is desirable. In this paper, we evaluate a
number of ICN caching strategies in regards to latency and hop count reduction
using IoT devices in a physical testbed. We find that the topology of the
network, and thus the routing algorithm used to generate forwarding
information, has a significant impact on the performance of a given caching
strategy. To the best of our knowledge, this is the first study that focuses on
latency effects in ICN-IoT caching while using real IoT hardware, and the first
to explicitly discuss the link between routing algorithm, network topology, and
caching effects.Comment: 10 pages, 9 figures, journal pape
Thermal analysis of cathode and anode regimes of an MPD arc Summary report, Jun. 1965 - Jan. 1967
Thermal analysis of anode and cathode heat transfer in magnetohydrodynamic electric arc
Thermal analysis of anode and cathode regimes in an electric arc column quarterly progress report no. 9, jul. 1 - sep. 30, 1965
Heat transfer phenomena in electric arcs - design and testing of arc tunnel modificatio
Longitudinal changes of spinal cord grey and white matter following spinal cord injury
Objectives: Traumatic and non-traumatic spinal cord injury produce neurodegeneration across the entire neuraxis. However, the spatiotemporal dynamics of spinal cord grey and white matter neurodegeneration above and below the injury is understudied. Methods: We acquired longitudinal data from 13 traumatic and 3 non-traumatic spinal cord injury patients (8-8 cervical and thoracic cord injuries) within 1.5 years after injury and 10 healthy controls over the same period. The protocol encompassed structural and diffusion-weighted MRI rostral (C2/C3) and caudal (lumbar enlargement) to the injury level to track tissue-specific neurodegeneration. Regression models assessed group differences in the temporal evolution of tissue-specific changes and associations with clinical outcomes. Results: At 2 months post-injury, white matter area was decreased by 8.5% and grey matter by 15.9% in the lumbar enlargement, while at C2/C3 only white matter was decreased (-9.7%). Patients had decreased cervical fractional anisotropy (FA: -11.3%) and increased radial diffusivity (+20.5%) in the dorsal column, while FA was lower in the lateral (-10.3%) and ventral columns (-9.7%) of the lumbar enlargement. White matter decreased by 0.34% and 0.35% per month at C2/C3 and lumbar enlargement, respectively, and grey matter decreased at C2/C3 by 0.70% per month. Conclusions: This study describes the spatiotemporal dynamics of tissue-specific spinal cord neurodegeneration above and below a spinal cord injury. While above the injury, grey matter atrophy lagged initially behind white matter neurodegeneration, in the lumbar enlargement these processes progressed in parallel. Tracking trajectories of tissue-specific neurodegeneration provides valuable assessment tools for monitoring recovery and treatment effects
The strong thirteen spheres problem
The thirteen spheres problem is asking if 13 equal size nonoverlapping
spheres in three dimensions can touch another sphere of the same size. This
problem was the subject of the famous discussion between Isaac Newton and David
Gregory in 1694. The problem was solved by Schutte and van der Waerden only in
1953.
A natural extension of this problem is the strong thirteen spheres problem
(or the Tammes problem for 13 points) which asks to find an arrangement and the
maximum radius of 13 equal size nonoverlapping spheres touching the unit
sphere. In the paper we give a solution of this long-standing open problem in
geometry. Our computer-assisted proof is based on a enumeration of the
so-called irreducible graphs.Comment: Modified lemma 2, 16 pages, 12 figures. Uploaded program packag
Longitudinal changes of spinal cord grey and white matter following spinal cord injury
Objectives: Traumatic and non-traumatic spinal cord injury produce neurodegeneration across the entire neuraxis. However, the spatiotemporal dynamics of spinal cord grey and white matter neurodegeneration above and below the injury is understudied. // Methods: We acquired longitudinal data from 13 traumatic and 3 non-traumatic spinal cord injury patients (8–8 cervical and thoracic cord injuries) within 1.5 years after injury and 10 healthy controls over the same period. The protocol encompassed structural and diffusion-weighted MRI rostral (C2/C3) and caudal (lumbar enlargement) to the injury level to track tissue-specific neurodegeneration. Regression models assessed group differences in the temporal evolution of tissue-specific changes and associations with clinical outcomes. // Results: At 2 months post-injury, white matter area was decreased by 8.5% and grey matter by 15.9% in the lumbar enlargement, while at C2/C3 only white matter was decreased (−9.7%). Patients had decreased cervical fractional anisotropy (FA: −11.3%) and increased radial diffusivity (+20.5%) in the dorsal column, while FA was lower in the lateral (−10.3%) and ventral columns (−9.7%) of the lumbar enlargement. White matter decreased by 0.34% and 0.35% per month at C2/C3 and lumbar enlargement, respectively, and grey matter decreased at C2/C3 by 0.70% per month. // Conclusions: This study describes the spatiotemporal dynamics of tissue-specific spinal cord neurodegeneration above and below a spinal cord injury. While above the injury, grey matter atrophy lagged initially behind white matter neurodegeneration, in the lumbar enlargement these processes progressed in parallel. Tracking trajectories of tissue-specific neurodegeneration provides valuable assessment tools for monitoring recovery and treatment effects
On Approximately Symmetric Informationally Complete Positive Operator-Valued Measures and Related Systems of Quantum States
We address the problem of constructing positive operator-valued measures
(POVMs) in finite dimension consisting of operators of rank one which
have an inner product close to uniform. This is motivated by the related
question of constructing symmetric informationally complete POVMs (SIC-POVMs)
for which the inner products are perfectly uniform. However, SIC-POVMs are
notoriously hard to construct and despite some success of constructing them
numerically, there is no analytic construction known. We present two
constructions of approximate versions of SIC-POVMs, where a small deviation
from uniformity of the inner products is allowed. The first construction is
based on selecting vectors from a maximal collection of mutually unbiased bases
and works whenever the dimension of the system is a prime power. The second
construction is based on perturbing the matrix elements of a subset of mutually
unbiased bases.
Moreover, we construct vector systems in \C^n which are almost orthogonal
and which might turn out to be useful for quantum computation. Our
constructions are based on results of analytic number theory.Comment: 29 pages, LaTe
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Abrupt thermal transition reveals hydrothermal boundary and role of seamounts within the Cocos Plate
New thermal data from 18–24 Ma lithosphere on the
Cocos Plate delineate contrasting subsurface thermal
conditions in adjacent sections of crust. Heat flow through
seafloor created at the East Pacific Rise is generally
suppressed by ~70% relative to conductive lithospheric
cooling models, whereas heat flow through adjacent,
similarly-aged lithosphere generated at the Cocos-Nazca
Spreading Center is consistent with these models. The
transition between thermal regimes is remarkably abrupt,
only 2–5 km wide, indicating a shallow hydrothermal origin.
The transition is more closely associated with differences in
the distribution of basement outcrops than with tectonic
boundaries, demonstrating the importance of the former in
extracting heat from the lithosphere on a regional basis
Linkage Mapping and Comparative Genomics Using Next-Generation RAD Sequencing of a Non-Model Organism
Restriction-site associated DNA (RAD) sequencing is a powerful new method for targeted sequencing across the genomes of many individuals. This approach has broad potential for genetic analysis of non-model organisms including genotype-phenotype association mapping, phylogeography, population genetics and scaffolding genome assemblies through linkage mapping. We constructed a RAD library using genomic DNA from a Plutella xylostella (diamondback moth) backcross that segregated for resistance to the insecticide spinosad. Sequencing of 24 individuals was performed on a single Illumina GAIIx lane (51 base paired-end reads). Taking advantage of the lack of crossing over in homologous chromosomes in female Lepidoptera, 3,177 maternally inherited RAD alleles were assigned to the 31 chromosomes, enabling identification of the spinosad resistance and W/Z sex chromosomes. Paired-end reads for each RAD allele were assembled into contigs and compared to the genome of Bombyx mori (n = 28) using BLAST, revealing 28 homologous matches plus 3 expected fusion/breakage events which account for the difference in chromosome number. A genome-wide linkage map (1292 cM) was inferred with 2,878 segregating RAD alleles inherited from the backcross father, producing chromosome and location specific sequenced RAD markers. Here we have used RAD sequencing to construct a genetic linkage map de novo for an organism that has no previous genome data. Comparative analysis of P. xyloxtella linkage groups with B. mori chromosomes shows for the first time, genetic synteny appears common beyond the Macrolepidoptera. RAD sequencing is a powerful system capable of rapidly generating chromosome specific data for non-model organisms
Double Digest RADseq: An Inexpensive Method for De Novo SNP Discovery and Genotyping in Model and Non-Model Species
The ability to efficiently and accurately determine genotypes is a keystone technology in modern genetics, crucial to studies ranging from clinical diagnostics, to genotype-phenotype association, to reconstruction of ancestry and the detection of selection. To date, high capacity, low cost genotyping has been largely achieved via “SNP chip” microarray-based platforms which require substantial prior knowledge of both genome sequence and variability, and once designed are suitable only for those targeted variable nucleotide sites. This method introduces substantial ascertainment bias and inherently precludes detection of rare or population-specific variants, a major source of information for both population history and genotype-phenotype association. Recent developments in reduced-representation genome sequencing experiments on massively parallel sequencers (commonly referred to as RAD-tag or RADseq) have brought direct sequencing to the problem of population genotyping, but increased cost and procedural and analytical complexity have limited their widespread adoption. Here, we describe a complete laboratory protocol, including a custom combinatorial indexing method, and accompanying software tools to facilitate genotyping across large numbers (hundreds or more) of individuals for a range of markers (hundreds to hundreds of thousands). Our method requires no prior genomic knowledge and achieves per-site and per-individual costs below that of current SNP chip technology, while requiring similar hands-on time investment, comparable amounts of input DNA, and downstream analysis times on the order of hours. Finally, we provide empirical results from the application of this method to both genotyping in a laboratory cross and in wild populations. Because of its flexibility, this modified RADseq approach promises to be applicable to a diversity of biological questions in a wide range of organisms
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