Trust and trustworthiness

What is it to trust someone? What is it for someone to be trustworthy? These are the two main questions that this paper addresses. There are various situations that can be described as ones of trust, but this paper considers the issue of trust between individuals. In it, I suggest that trust is distinct from reliance or cases where someone asks for something on the expectation that it will be done due to the different attitude taken by the trustor. I argue that the trustor takes Holton's 'participant stance' and this distinguishes trust from reliance. I argue that trustworthiness is different from reliability and that an account of trustworthiness cannot be successful whilst ignoring the point that aligning trustworthiness with reliability removes the virtue from being trustworthy. On the question of what it is distinguishes trustworthiness from reliability, I argue that the distinction is in the opportunity for the trustee to act against the wishes of the trustor and the trustee's consideration of the value of the trust that has been placed in them by the trustor

Big Data: The Engine to Future Cities—A Reflective Case Study in Urban Transport

In an era of smart cities, artificial intelligence and machine learning, data is purported to be the ‘new oil’, fuelling increasingly complex analytics and assisting us to craft and invent future cities. This paper outlines the role of what we know today as big data in understanding the city and includes a summary of its evolution. Through a critical reflective case study approach, the research examines the application of urban transport big data for informing planning of the city of Sydney. Specifically, transport smart card data, with its diverse constraints, was used to understand mobility patterns through the lens of the 30 min city concept. The paper concludes by offering reflections on the opportunities and challenges of big data and the promise it holds in supporting data-driven approaches to planning future cities

QNDE Topical Forum Total Quality Management — TQM

The emerging world economy presents challenges to all industrial nations in productivity, product reliability and customer confidence level. The challenges are being met in various nations by reorienting industries for the production and marketing of “world class” products. Such reorientation requires significant cultural changes, significant improvements in management and judicious implementation of new and developing technologies. Reorientation to “world class” production has been implemented in the United States of America by a Department of Defense initiative that is known as “Total Quality Management or TQM”

DESIGNING PRECINTS IN THE DENSIFYING CITY – THE ROLE OF PLANNING SUPPORT SYSTEMS

Australia’s cities face significant social, economic and environmental challenges, driven by population growth and rapid urbanisation. The pressure to increase housing availability will lead to greater levels of high-density and medium-density stock. However, there is enormous political and community pushback against this. One way to address this challenge is to encourage medium-density living solutions through “precinct” scale development. Precinct-scale development has the potential to include additional hard and soft infrastructure that may offset the perceived negativities of higher densities. As part of Australian research into precinct-scale development, and as part of our broader Smart Cities approach, or more specifically City Analytics approach, new digital planning tools &ndash; Envision and ESP &ndash; have been developed to support scenario planning and design needs. They utilise a data-driven and scenario planning approach underpinned by Geographic Information System (GIS) functionality.We focus on a case study in the City of Blacktown, Western Sydney, New South Wales, Australia. By 2036 Blacktown is forecast to grow to approximately 500,000 people (an increase of over 30&thinsp;%) and 180,000 dwellings. Most new dwellings will be delivered through urban infill. The Blacktown master plan promotes higher density housing, mixed employment uses and continued improvements to the public domain. Our study provides a unique opportunity to implement this broad strategy within a specific case and location. Specifically, this paper provides information on how these digital planning tools supported Blacktown planners in identifying, co-designing and implementing a new approach for precinct level planning. It also presents the results of an evaluation of digital-planning tools in the context of the Blacktown case study.</p

A Co-design Prototyping Approach for Buiding a Precinct Planning Tool

As the world is becoming increasingly urbanized there is a need for more sustainability-oriented planning of our cities. Policy and decision-makers are interested in the use of evidenced based approaches and tools that will support collaborative planning. There are a number of tools in the domain of spatial planning and decision support systems that have been built over the last few decades but the uptake and use of these tools is somewhat limited. In the context of Australia there is significant urban growth occurring across the major cities and a need to provision planners and developers with precinct planning tools to assist in managing infill and the densification of the existing urban fabric in a carbon constrained economy. In this paper we describe the development of a new precinct planning tool known as the Envision Scenario Planner (ESP), which is being applied initially in two cities, Melbourne and Perth to assist in the urban design and planning of Greyfield sites. To set the scene in this paper we firstly provide a brief review of the existing state of play of visualization and modelling tools available to urban planners in Australia. The focus on the paper will be to introduce an iterative co-design prototyping approach for developing a best practice precinct planning support tool (ESP) from an earlier tool known as ENVISION. The first step of the approach is an exposure workshop with experts to refine the proposed tool workflow and its functionality. Subsequent iterations of the prototype are then exposed to larger audiences for validation and testing. In this paper we will describe the process and the preliminary findings in implementing the first phase of this iterative co-design prototype approach

Analysis of Primary Risk Factors for Oral Cancer from US States with Increasing Rates

Objectives To examine the primary risk factor for oral cancer in the US, smoking and tobacco use, among the specific US states that experienced short-term increases in oral cancer incidence and mortality. Methods Population-based data on oral cancer morbidity and mortality in the US were obtained from the National Cancer Institute\u27s (NCI) Surveillance, Epidemiology, and End Results (SEER) database for analysis of recent trends. Data were also obtained from the Centers for Disease Control and Prevention (CDC) Behavioral Risk Factor Surveillance System (BRFSS) to measure current and former trends of tobacco usage. To comprehensive measures of previous state tobacco use and tobacco-related policies, the Initial Outcomes Index (IOI, 1992-1993) and the Strength of Tobacco Control index (SoTC, 1999-2000) were also used for evaluation and comparison. Results Analysis of the NCI-SEER data confirmed a previous report of geographic increases in oral cancer and demonstrated these were state-specific, were not regional, and were unrelated to previously observed increases among females and minorities. Analysis of the CDC-BRFSS data revealed these states had relatively higher percentages of smokers currently, as well as historically. In addition, analysis of the IOI and SoTC indexes suggest that many factors, including cigarette pricing, taxes and home or workplace bans, may have had significant influence on smoking prevalence in these areas. Trend analysis of these data uncovered a recent and significant reversal in smoking rates that suggest oral cancer incidence and mortality may also begin to decline in the near future. Conclusion Due to the rising costs of health care in the US and the limited resources available for health prevention efforts, it is essential to organize and direct more effective efforts by public health officials and epidemiologists, as well as funding from local, state and federal governments, to reduce and eliminate identified health disparities. This study provides evidence how these efforts may be directed to specific geographic areas, and towards the white males, previously thought to be unaffected by the increases in oral cancer among females and minorities

Dietary Methionine Restriction Regulates Liver Protein Synthesis and Gene Expression Independently of Eukaryotic Initiation Factor 2 Phosphorylation in Mice

Background: The phosphorylation of eukaryotic initiation factor 2 (p-eIF2) during dietary amino acid insufficiency reduces protein synthesis and alters gene expression via the integrated stress response (ISR).Objective: We explored whether a Met-restricted (MR) diet activates the ISR to reduce body fat and regulate protein balance.Methods: Male and female mice aged 3-6 mo with either whole-body deletion of general control nonderepressible 2 (Gcn2) or liver-specific deletion of protein kinase R-like endoplasmic reticulum kinase (Perk) alongside wild-type or floxed control mice were fed an obesogenic diet sufficient in Met (0.86%) or an MR (0.12% Met) diet for ≤5 wk. Ala enrichment with deuterium was measured to calculate protein synthesis rates. The guanine nucleotide exchange factor activity of eIF2B was measured alongside p-eIF2 and hepatic mRNA expression levels at 2 d and 5 wk. Metabolic phenotyping was conducted at 4 wk, and body composition was measured throughout. Results were evaluated with the use of ANOVA (P < 0.05).Results: Feeding an MR diet for 2 d did not increase hepatic p-eIF2 or reduce eIF2B activity in wild-type or Gcn2-/- mice, yet many genes transcriptionally regulated by the ISR were altered in both strains in the same direction and amplitude. Feeding an MR diet for 5 wk increased p-eIF2 and reduced eIF2B activity in wild-type but not Gcn2-/- mice, yet ISR-regulated genes altered in both strains similarly. Furthermore, the MR diet reduced mixed and cytosolic but not mitochondrial protein synthesis in both the liver and skeletal muscle regardless of Gcn2 status. Despite the similarities between strains, the MR diet did not increase energy expenditure or reduce body fat in Gcn2-/- mice. Finally, feeding the MR diet to mice with Perk deleted in the liver increased hepatic p-eIF2 and altered body composition similar to floxed controls.Conclusions: Hepatic activation of the ISR resulting from an MR diet does not require p-eIF2. Gcn2 status influences body fat loss but not protein balance when Met is restricted

Anatomical traits associated with pod rot resistance in peanut.

Anatomical traits associated with pod resistance in peanut