2,860 research outputs found
Ancient Egypt 1923 Part 2
Part 2 of the 1923 Ancient Egypt books. Contents include the tomb at Byblos, a tomb with Aramaic inscriptions, the British school at Qau, the magic skin, Apries and the possibility of royal blood, and obelisks at Pylon VII.https://knowledge.e.southern.edu/kweeks_coll/1023/thumbnail.jp
Influence of leaf ageing, leaf area and crop load on photosynthesis, stomatal conductance and senescence of grapevine (Vitis vinifera L. cv. Pinot noir) leaves
Treatments varying the leaf area (source) to crop load (sink) balance of pot-grown Pinot noir vines caused differences in the photosynthesis (Pn) rates of the fourth leaf, 48 h after they were applied. Stomatal conductance was only affected by leaf removal, not by the presence or absence of crop. The vines with and without crop were subject to a range of leaf removal treatments. All treatments retained leaves at nodes 1-4 from the shoot base and then had 100%(control), 66 %, 33 %, or 0 % leaves retained from node 5 to the apex of the shoot. Leaf removal elevated the Pn rate of the fourth leaf, but there was no difference in Pn rate between vines with or without crop pre-veraison. From veraison on the photosynthetic rate of vines with crop and 100 % leaves retained increased. Similar, high Pn rate was also observed for vines without crop and 0 % leaves retained. The lower Pn rate of vines with crop pre-veraison suggests that there is potential to increase vine productivity in this period. The Pn rate of vines without crop, 100 % and 66 % leaves retained declined from 15 d after treatment. Average Pn of all treatments over the 4 measurements prior to harvest was positively correlated with the vine leaf area (source) to total vine dry weight (sink) ratio. Leaves of vines with a high source:sink ratio (without crop, 100, 66 or 33%leaves retained) senesced i.e. decreased in chlorophyll content more rapidly than leaves of the low source to sink ratio treatments. Results indicate that the decline in grapevine leaf Pn, previously associated with advanced leaf age is actually caused by a progressive increase in leaf area to fruit weight (source:sink) ratio, as leaves emerge on the developing vine
Magnetohydrostatic solar prominences in near-potential coronal magnetic fields
We present numerical magnetohydrostatic solutions describing the
gravitationally stratified, bulk equilibrium of cool, dense prominence plasma
embedded in a near-potential coronal field. These solutions are calculated
using the FINESSE magnetohydrodynamics equilibrium solver and describe the
morphologies of magnetic field distributions in and around prominences and the
cool prominence plasma that these fields support. The equilibrium condition for
this class of problem is usually different in distinct subdomains, separated by
free boundaries, across which solutions are matched by suitable continuity or
jump conditions describing force balance. We employ our precise finite element
elliptic solver to calculate solutions not accessible by previous analytical
techniques with temperature or entropy prescribed as free functions of the
magnetic flux function, including a range of values of the polytropic index,
temperature variations mainly across magnetic field lines and photospheric
field profiles sheared close to the polarity inversion line. Out of the many
examples computed here, perhaps the most noteworthy is one which reproduces
precisely the three-part structure often encountered in observations: a cool
dense prominence within a cavity/flux rope embedded in a hot corona. The
stability properties of these new equilibria, which may be relevant to solar
eruptions, can be determined in the form of a full resistive MHD spectrum using
a companion hyperbolic stability solver.Comment: To appear in ApJ August 200
Hospital costs of out-of-hospital cardiac arrest patients treated in intensive care; a single centre evaluation using the national tariff-based system
OBJECTIVES: There is a scarcity of literature reporting hospital costs for treating out of hospital cardiac arrest (OOHCA) survivors, especially within the UK. This is essential for assessment of cost-effectiveness of interventions necessary to allow just allocation of resources within the National Health Service. We set out primarily to calculate costs stratified against hospital survival and neurological outcomes. Secondarily, we estimated cost effectiveness based on estimates of survival and utility from previous studies to calculate costs per quality adjusted life year (QALY). SETTING: We performed a single centre (London) retrospective review of in-hospital costs of patients admitted to the intensive care unit (ICU) following return of spontaneous circulation (ROSC) after OOHCA over 18â
months from January 2011 (following widespread introduction of targeted temperature management and primary percutaneous intervention). PARTICIPANTS: Of 69 successive patients admitted over an 18-month period, survival and cerebral performance category (CPC) outcomes were obtained from review of databases and clinical notes. The Trust finance department supplied ICU and hospital costs using the Payment by Results UK system. RESULTS: Of those patients with ROSC admitted to ICU, survival to hospital discharge (any CPC) was 33/69 (48%) with 26/33 survivors in CPC 1â2 at hospital discharge. Cost per survivor to hospital discharge (including total cost of survivors and non-survivors) was ÂŁ50â
000, cost per CPC 1â2 survivor was ÂŁ65â
000. Cost and length of stay of CPC 1â2 patients was considerably lower than CPC 3â4 patients. The majority of the costs (69%) related to intensive care. Estimated cost per CPC 1â2 survivor per QALY was ÂŁ16â
000. CONCLUSIONS: The costs of in-hospital patient care for ICU admissions following ROSC after OOHCA are considerable but within a reasonable threshold when assessed from a QALY perspective
Clinical and echocardiographic characteristics and cardiovascular outcomes according to diabetes status in patients with heart failure and preserved ejection fraction. A report from the Irbesartan in Heart Failure with Preserved Ejection Fraction Trial (I-Preserve)
BackgroundâIn patients with HF and preserved ejection fraction (HFpEF), little is known about the characteristics of and outcomes in those with and without diabetes.
MethodsâWe examined clinical and echocardiographic characteristics and outcomes in the Irbesartan in Heart Failure with Preserved Ejection Fraction trial (I-Preserve), according to history of diabetes. Cox regression models were used to estimate hazard ratios (HR) for cardiovascular outcomes adjusted for known predictors, including age, sex, natriuretic peptides, and comorbidity. Echocardiographic data were available in 745 patients and were additionally adjusted for in supplementary analyses.
ResultsâOverall, 1134 of 4128 patients (27%) had diabetes. Compared to those without diabetes, they were more likely to have a history of myocardial infarction (28% vs. 22%), higher BMI (31kg/m2 vs. 29kg/m2), worse Minnesota living with HF score (48 vs. 40), higher median NT-proBNP concentration (403 vs 320 pg/ml; all p<0.01), more signs of congestion but no significant difference in LVEF. Patients with diabetes had a greater left ventricular (LV) mass and left atrial area than patients without diabetes. Doppler E wave velocity (86 vs 76 cm/sec, p<0.0001) and the ratio of E/e' (11.7 vs 10.4, p=0.010) were higher in patients with diabetes. Over a median follow-up of 4.1 years, cardiovascular death or HF hospitalization occurred in 34% of patients with diabetes vs. 22% of those without diabetes; adjusted HR 1.75 (95% CI 1.49-2.05) and 28% vs. 19% of patients with and without diabetes died; adjusted HR 1.59 (1.33-1.91).
ConclusionsâIn HFpEF, patients with diabetes have more signs of congestion, worse quality of life, higher NT-proBNP levels, and a poorer prognosis. They also display greater structural and functional echocardiographic abnormalities. Further investigation is needed to determine the mediators of the adverse impact of diabetes on outcomes in HFPEF, and whether they are modifiable
H-index pathology: Implications for medical researchers and practitioners
The h-index has quickly become the standard method by which medical schools judge the impact of medical researchers. Rob Horne, Keith Petrie, and Simon Wessely describe a cluster of potentially pathological behaviours associated with the index
Downâregulation of key genes involved in carbon metabolism in Medicago truncatula results in increased lipid accumulation in vegetative tissue
Alfalfa (Medicago sativa L.), is the most widely grown perennial forage crop, which is a close relative of the model diploid legume Medicago truncatula. However, use of alfalfa lead to substantial greenhouse gas emissions and economic losses related to inefficiencies in rumen fermentation. The provision of supplemental lipids has been used as a strategy to mitigate these issues, but it is a costly approach. The ability to enhance lipid content within the vegetative tissues of alfalfa would therefore be very advantageous. As such, our aim was to assess and select gene candidates to increase total shoot lipid content in M. truncatula using a virusâinduced gene silencing (VIGS) approach. We targeted gene homologs of the SUGARâDEPENDANT 1 (SDP1), ADPâGLUCOSEâPYROPHOSPHORYLASE SMALL SUBUNIT 1 (APS1), TRIGALACTOSYLDIACYLGLYCEROL 5 (TGD5) and PEROXISOMAL ABC TRANSPORTER 1 (PXA1) in M. truncatula for silencing. Reduced target transcript levels were confirmed and changes of shoot lipid content and fatty acid composition were measured. Silencing of SDP1, APS1 and PXA1 each resulted in significant increases in shoot total lipid content. Significantly increased proportions of αâlinolenic acid (18:3Î9cis,12cis,15cis) were observed and stearic acid (18:0) levels significantly decreased in the total acyl lipids extracted from vegetative tissues of each of the M. truncatula silenced plants. In contrast, palmitic acid (16:0) levels were significantly decreased in only SDP1 and PXA1âsilenced plants. Genes of PXA1 and SDP1 would be ideal targets for mutation as a means of improving the quality of alfalfa for increasing feed efficiency and minimizing greenhouse gas emissions from livestock production in the future
Toward detailed prominence seismology - I. Computing accurate 2.5D magnetohydrodynamic equilibria
Context. Prominence seismology exploits our knowledge of the linear
eigenoscillations for representative magnetohydro- dynamic models of filaments.
To date, highly idealized models for prominences have been used, especially
with respect to the overall magnetic configurations.
Aims. We initiate a more systematic survey of filament wave modes, where we
consider full multi-dimensional models with twisted magnetic fields
representative of the surrounding magnetic flux rope. This requires the ability
to compute accurate 2.5 dimensional magnetohydrodynamic equilibria that balance
Lorentz forces, gravity, and pressure gradients, while containing density
enhancements (static or in motion).
Methods. The governing extended Grad-Shafranov equation is discussed, along
with an analytic prediction for circular flux ropes for the Shafranov shift of
the central magnetic axis due to gravity. Numerical equilibria are computed
with a finite element-based code, demonstrating fourth order accuracy on an
explicitly known, non-trivial test case.
Results. The code is then used to construct more realistic prominence
equilibria, for all three possible choices of a free flux-function. We quantify
the influence of gravity, and generate cool condensations in hot cavities, as
well as multi- layered prominences.
Conclusions. The internal flux rope equilibria computed here have the
prerequisite numerical accuracy to allow a yet more advanced analysis of the
complete spectrum of linear magnetohydrodynamic perturbations, as will be
demonstrated in the companion paper.Comment: Accepted by Astronomy & Astrophysics, 15 pages, 15 figure
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