559 research outputs found

    Start Making Sense: Predicting confidence in virtual human interactions using biometric signals

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    This is volume 1 of the Measuring Behavior 2020-21 Conference. Volume 2 will follow when the conference takes place in October 2021. www.measuringbehavior.orgPublisher PD

    Mikrogliazellen beim plötzlichen Kindstod

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    Die Forschung zum plötzlichen Kindstod hat viele verschiedene Faktoren aufgedeckt, die auf unterschiedlichen Wegen zum SIDS (sudden infant death syndrome) Ereignis führen. In der vorliegenden Arbeit sind 23 Gehirne von SIDS-Fällen und 7 Gehirne von Kindern mit bekannten Todesursachen untersucht worden. In jedem Gehirn sind mikroskopisch 35 Regionen betrachtet worden. Die Anzahl an Mikrogliazellen, die dort aktiviert als Marker von Zellschädigung gelten, wurde dokumentiert. Nur in einer Region, dem Kerngebiet des zwölften Hirnnerven, der die Zungenmuskulatur innerviert und die oberen Atemwege tonisieren und damit offenhalten kann, fanden sich bei den Opfern des plötzlichen Kindstodes signifikant mehr Mikrogliazellen als bei den Kontroll-Fällen. Eine unspezifische Reaktion wie die Zunahme der Mikrogliazellenpopulation kann über einen fehlerhaft abgelaufenen Prozess, der zum plötzlichen Kindstod fährt, wenig aussagen. Jedoch weisen die hohen Mikrogliazellzahlen auf Zellstress in der Region des Nucleus hypoglossus hin und es ist möglich, dass eine pathologische Veränderung im Kern des zwölften Hirnnerven im Geschehen des plötzlichen Kindstodes eine Rolle spielt

    Clinical Interventions to Promote Breastfeeding by Latinas: A Meta-analysis

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    Breastfeeding duration and exclusivity among Latinas fall below recommended levels, indicating a need for targeted interventions. The effectiveness of clinical breastfeeding interventions for Latinas remains unclear

    Salivary Metabolomic Signatures and Body Mass Index in Italian Adolescents: A Pilot Study

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    Context: Obesity surveillance is scarce in adolescents, and little is known on whether salivary metabolomics data, emerging minimally invasive biomarkers, can characterize metabolic patterns associated with overweight or obesity in adolescents. Objective: This pilot study aims to identify the salivary molecular signatures associated with body mass index (BMI) in Italian adolescents. Methods: Saliva samples and BMI were collected in a subset of n = 74 young adolescents enrolled in the Public Health Impact of Metal Exposure study (2007-2014). A total of 217 untargeted metabolites were identified using liquid chromatography-high resolution mass spectrometry. Robust linear regression was used to cross-sectionally determine associations between metabolomic signatures and sex-specific BMI-for-age z-scores (z-BMI). Results: Nearly 35% of the adolescents (median age: 12 years; 51% females) were either obese or overweight. A higher z-BMI was observed in males compared to females (P = .02). One nucleoside (deoxyadenosine) and 2 lipids (18:0-18:2 phosphatidylcholine and dipalmitoyl-phosphoethanolamine) were negatively related to z-BMI (P < .05), whereas 2 benzenoids (3-hydroxyanthranilic acid and a phthalate metabolite) were positively associated with z-BMI (P < .05). In males, several metabolites including deoxyadenosine, as well as deoxycarnitine, hyodeoxycholic acid, N-methylglutamic acid, bisphenol P, and trigonelline were downregulated, while 3 metabolites (3-hydroxyanthranilic acid, theobromine/theophylline/paraxanthine, and alanine) were upregulated in relation to z-BMI (P < .05). In females, deoxyadenosine and dipalmitoyl-phosphoethanolamine were negatively associated with z-BMI while deoxycarnitine and a phthalate metabolite were positively associated (P < .05). A single energy-related pathway was enriched in the identified associations in females (carnitine synthesis, P = .04). Conclusion: Salivary metabolites involved in nucleotide, lipid, and energy metabolism were primarily altered in relation to BMI in adolescents

    STIRAP transport of Bose-Einstein condensate in triple-well trap

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    The irreversible transport of multi-component Bose-Einstein condensate (BEC) is investigated within the Stimulated Adiabatic Raman Passage (STIRAP) scheme. A general formalism for a single BEC in M-well trap is derived and analogy between multi-photon and tunneling processes is demonstrated. STIRAP transport of BEC in a cyclic triple-well trap is explored for various values of detuning and interaction between BEC atoms. It is shown that STIRAP provides a complete population transfer at zero detuning and interaction and persists at their modest values. The detuning is found not to be obligatory. The possibility of non-adiabatic transport with intuitive order of couplings is demonstrated. Evolution of the condensate phases and generation of dynamical and geometric phases are inspected. It is shown that STIRAP allows to generate the unconventional geometrical phase which is now of a keen interest in quantum computing.Comment: 9 pages, 6 figures. To be published in Laser Physics (v. 19, n.4, 2009

    Association between circulating levels of sex steroid hormones and esophageal adenocarcinoma in the FINBAR Study

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    Funding: The study was supported by NIH Intramural Research Program, National Cancer Institute; Cancer Focus Northern Ireland (formerly the Ulster Cancer Foundation); the Northern Ireland R&D office; and the Health Research Board, Ireland. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.Peer reviewedPublisher PD
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