1,309 research outputs found

    NLO Quarkonium Production in Hadronic Collisions

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    We present some preliminary results on the next-to-leading order calculation in QCD of quarkonium production cross sections in hadronic collisions. We will show that the NLO total cross sections for PP-wave states produced at high energy are not reliable, due to the appearance of very large and negative contributions. We also discuss some issues related to the structure of final states in colour-octet production and to high-p_T fragmentation.Comment: 11 pages, Latex, epsfig, 4 figures. To appear in the proceedings of the Quarkonium Physics Workshop, University of Illinois, Chicago, June199

    Astrocytes and Microglia and Their Potential Link with Autism Spectrum Disorders.

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    The cellular mechanism(s) underlying autism spectrum disorders (ASDs) are not fully understood although it has been shown that various genetic and environmental factors contribute to their etiology. As increasing evidence indicates that astrocytes and microglial cells play a major role in synapse maturation and function, and there is evidence of deficits in glial cell functions in ASDs, one current hypothesis is that glial dysfunctions directly contribute to their pathophysiology. The aim of this review is to summarize microglia and astrocyte functions in synapse development and their contributions to ASDs

    High prevalence of clonally diverse spa type t026 staphylococcus aureus contaminating rural eggshells

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    Purpose. The presence of Staphylococcus aureus in poultry and poultry products, including eggs, increases its potential to enter the food chain, resulting in foodborne diseases. In this context, eggshell colonization by staphylococci may represent a risk factor. This study aimed to investigate the contamination of rural eggshell by S. aureus and to characterize the key features of the isolated strains. Methodology. Antibiotic resistance was assessed by disc diffusion. Resistant isolates were analysed by PCR for the identification of associated genetic determinants of resistance. PCR was also used to screen for the presence of genes coding for toxins, namely, sea, sec, sei, sem, seo and tst. The genetic characterization was extended by means of agr locus typing and spa typing. Results. 34 S. aureus were isolated. Macrolide-and tetracycline-resistant strains were prevalent. All strains were susceptible to oxacillin, cefoxitin and trimethoprim-sulfamethoxazole. PCR screening for genes encoding enterotoxins detected several virulence patterns, which, together with spa-typing and agr-locus typing, allowed cluster analysis and the description of novel clones. Conclusion. Continuous monitoring of staphylococci is needed also in rural or natural settings. Increasing the number of samples and expanding the geographical region will be needed to further extend the significance of the study

    Identification of onosma visianii roots extract and purified shikonin derivatives as potential acaricidal agents against tetranychus urticae

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    There is an increasing need for the discovery of reliable and eco-friendly pesticides and natural plant-derived products may play a crucial role as source of new active compounds. In this research, a lipophilic extract of Onosma visianii roots extract containing 12% of shikonin derivatives demonstrated significant toxicity and inhibition of oviposition against Tetranychus urticae mites. Extensive chromatographic separation allowed the isolation of 11 naphthoquinone derivatives that were identified by spectral techniques and were tested against Tetranychus urticae. All the isolated compounds presented effects against the considered mite and isobutylshikonin (1) and isovalerylshikonin (2) were the most active, being valuable model compounds for the study of new anti-mite agents

    Numerical simulation of 3D free surface flows in time dependent curvilinear coordinates

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    We propose a three dimensional non-hydrostatic shock-capturing numerical model for the simulation of wave propagation, transformation and breaking, which is based on an original integral formulation of the contravariant Navier-Stokes equations, devoid of Christoffel symbols, in general time-dependent curvilinear coordinates

    Balancing adaptivity and customisation : in search of sustainable personalisation in cultural heritage

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    Personalisation for cultural heritage aims at delivering to visitors the right stories at the right time. Our endeavour to determine which features to use for adaptation starts from acknowledging what forms of personalisation curators value as most meaningful. Working in collaboration with curators we have explored the different features that must be taken into account: some are related to the content (multiple interpretation layers), others to the context of delivery (where and when), but some are idiosyncratic (“match my mood”, “something that is relevant to my life”). The findings reveal that a sustainable personalization needs to accurately balance: (i) support to curators in customising stories to different visitors; (ii) algorithms for the system to dynamically model aspects of the visit and instantiate the correct behaviour; and (iii) an active role for visitors to choose the type of experience they would like to have today

    Colloidal CuFeS2 Nanocrystals: Intermediate Fe d-Band Leads to High Photothermal Conversion Efficiency

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    We describe the colloidal hot-injection synthesis of phase-pure nanocrystals (NCs) of a highly abundant mineral, chalcopyrite (CuFeS2). Absorption bands centered at around 480 and 950 nm, spanning almost the entire visible and near infrared regions, encompass their optical extinction characteristics. These peaks are ascribable to electronic transitions from the valence band (VB) to the empty intermediate band (IB), located in the fundamental gap and mainly composed of Fe 3d orbitals. Laser-irradiation (at 808 nm) of an aqueous suspension of CuFeS2 NCs exhibited significant heating, with a photothermal conversion efficiency of 49%. Such efficient heating is ascribable to the carrier relaxation within the broad IB band (owing to the indirect VB-IB gap), as corroborated by transient absorption measurements. The intense absorption and high photothermal transduction efficiency (PTE) of these NCs in the so-called biological window (650-900 nm) makes them suitable for photothermal therapy as demonstrated by tumor cell annihilation upon laser irradiation. The otherwise harmless nature of these NCs in dark conditions was confirmed by in vitro toxicity tests on two different cell lines. The presence of the deep Fe levels constituting the IB is the origin of such enhanced PTE, which can be used to design other high performing NC photothermal agents.Comment: 12 pages, Chemistry of Materials, 31-May-201

    Lipomatous hypertrophy: an accidental finding in heart

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    Lipomatous hypertrophy is an uncommon benign lesion of the atrium, generally asymptomatic, characterized by unencapsulated accumulation of adipose tissue entrapping cardiomyocytes. This pathology generally remains unnoticed and often emerges as an occasional finding. Here, we report two cases from our hospital including a review of the available literature
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