333 research outputs found
Environmental Control and Life Support System (ECLSS) System Engineering Workshop
This slide presentation begins with a recap on a previous lecture on the ECLSS subsystems, and the various types (i.e., Non-regenerative vs Regenerative, open loop vs closed loop, and physical-chemical vs bioregenerative) It also recaps the Equivalent system mass (ESM) metric. The presentation continues with a review of the ECLSS of the various NASA manned space exploration programs from Mercury, to the current planned Altair lunar landing, and Lunar base operations. There is also a team project to establish the ESM of two conceptualized missions
National Aeronautics and Space Administration (NASA) Environmental Control and Life Support (ECLS) Integrated Roadmap Development
Although NASA is currently considering a number of future human space exploration mission concepts, detailed mission requirements and vehicle architectures remain mostly undefined, making technology investment strategies difficult to develop and sustain without a top-level roadmap to serve as a guide. This paper documents the process and results of an effort to define a roadmap for Environmental Control and Life Support Systems (ECLSS) capabilities required to enhance the long-term operation of the International Space Station (ISS) as well as enable beyond-Low Earth Orbit (LEO) human exploration missions. Three generic mission types were defined to serve as a basis for developing a prioritized list of needed capabilities and technologies. Those are 1) a short duration micro-gravity mission; 2) a long duration microgravity mission; and 3) a long duration partial gravity (surface) exploration mission. To organize the effort, a functional decomposition of ECLSS was completed starting with the three primary functions: atmosphere, water, and solid waste management. Each was further decomposed into sub-functions to the point that current state-of-the-art (SOA) technologies could be tied to the sub-function. Each technology was then assessed by NASA subject matter experts as to its ability to meet the functional needs of each of the three mission types. When SOA capabilities were deemed to fall short of meeting the needs of one or more mission types, those gaps were prioritized in terms of whether or not the corresponding capabilities enable or enhance each of the mission types. The result was a list of enabling and enhancing capability needs that can be used to guide future ECLSS development, as well as a list of existing hardware that is ready to go for exploration-class missions. A strategy to fulfill those needs over time was then developed in the form of a roadmap. Through execution of this roadmap, the hardware and technologies intended to meet exploration needs will, in many cases, directly benefit the ISS operational capability, benefit the Multi-Purpose Crew Vehicle (MPCV), and guide long-term technology investments for longer duration missions
National Aeronautics and Space Administration (NASA) Environmental Control and Life Support (ECLS) Capability Roadmap Development for Exploration
NASA is considering a number of future human space exploration mission concepts. Although detailed requirements and vehicle architectures remain mostly undefined, near-term technology investment decisions need to be guided by the anticipated capabilities needed to enable or enhance the mission concepts. This paper describes a roadmap that NASA has formulated to guide the development of Environmental Control and Life Support Systems (ECLSS) capabilities required to enhance the long-term operation of the International Space Station (ISS) and enable beyond-Low Earth Orbit (LEO) human exploration missions. Three generic mission types were defined to serve as a basis for developing a prioritized list of needed capabilities and technologies. Those are 1) a short duration micro gravity mission; 2) a long duration transit microgravity mission; and 3) a long duration surface exploration mission. To organize the effort, ECLSS was categorized into three major functional groups (atmosphere, water, and solid waste management) with each broken down into sub-functions. The ability of existing, flight-proven state-of-the-art (SOA) technologies to meet the functional needs of each of the three mission types was then assessed. When SOA capabilities fell short of meeting the needs, those "gaps" were prioritized in terms of whether or not the corresponding capabilities enable or enhance each of the mission types. The resulting list of enabling and enhancing capability gaps can be used to guide future ECLSS development. A strategy to fulfill those needs over time was then developed in the form of a roadmap. Through execution of this roadmap, the hardware and technologies needed to enable and enhance exploration may be developed in a manner that synergistically benefits the ISS operational capability, supports Multi-Purpose Crew Vehicle (MPCV) development, and sustains long-term technology investments for longer duration missions. This paper summarizes NASA s ECLSS capability roadmap development process, findings, and recommendatio
Environmental Control and Life Support (ECLS) Integrated Roadmap Development
This white paper documents a roadmap for development of Environmental Control and Life Support (ECLS) Systems (ECLSS) capabilities required to enable beyond-Low Earth Orbit (LEO) Exploration missions. In many cases, the execution of this Exploration-based roadmap will directly benefit International Space Station (ISS) operational capability by resolving known issues and/or improving overall system reliability. In addition, many of the resulting products will be applicable across multiple Exploration elements such as Multi-Purpose Crew Vehicle (MPCV), Multi-Mission Space Exploration Vehicle (MMSEV), Deep Space Habitat (DSH), and Landers. Within the ECLS community, this white paper will be a unifying tool that will improve coordination of resources, common hardware, and technologies. It will help to align efforts to focus on the highest priority needs that will produce life support systems for future human exploration missions that will simply run in the background, requiring minimal crew interaction
The Chattanooga Procedure: A New Technique Used for Anterior Multi-level Cervical Fusions
STUDY DESIGN: A preliminary assessment of anterior cervical fusion performed with interbody cage and DOC plate.
OBJECTIVES: To describe and evaluate the efficacy and safety of the Chattanooga Procedure , a modified technique in achieving anterior cervical fusion.
SUMMARY OF BACKGROUND DATA: Anterior cervical fusion with interbody bone graft and anterior plating is connnonly performed. Unfortunately, the plate has been reported to shield the graft from loading thus reducing fusion rates. The use of interbody fusion cages has been effective in the lumbar spine and has gained acceptance in the cervical spine.
METHODS:. Twenty-five patients received The Chattanooga Procedure between 7/24/98 and 4/8/99. All patients had anterior discectomies and carpectomies, placement of a Harms cage packed with carpectomy bone, and application ofDePuy-Acromed DOC. Fusion was defined by radiographic evidence of trabecular bone bridging across the Harms cage. CT scans were performed on twelve randomly chosen patients to verify fusion. No external bracing was used except a soft collar as needed. Pre- and post-operative pain and functional capacity data were collected and statistically analyzed using paired t-tests.
RESULTS: There were no cases of pseudoarthrosis, major neurological, vascular, or wound complications. Only one case of unresolved dysphasia was noted. The average operative time (11 0 minutes) was comparable to standard instrumented multi-level anterior cervical fusion surgeries. The average estimated blood loss was 113 ml (range, 50-750 ml). Both visual analog pain scale and Oswestry functional capacity data were significantly improved post-operatively (p\u3c 0.01).
DISCUSSION: Advantages of the Chattanooga Procedure include immediate stability, support, elimination of donor site pain to iliac crest bone autograft, and a decrease in pseudoarthrosis by dividing the fusion surfaces by half. Concerns regarding this technique include an increased risk for dysphasia due to the DOC\u27s high profile. Pseudoarthrosis or instrumentation migration could also become problematic since the removal of the Harms cage could be difficult if necessary
Rapid generation of an anthrax immunotherapeutic from goats using a novel non-toxic muramyl dipeptide adjuvant
The Effectiveness of Total Worker Health Interventions: A Systematic Review for a National Institutes of Health Pathways to Prevention Workshop
BACKGROUND: The Total Worker Health (TWH) program of the National Institute for Occupational Safety and Health aims to advance worker well-being by integrating injury and illness prevention efforts with work-related safety and health hazard efforts.
PURPOSE: To evaluate evidence on the benefits and harms of integrated TWH interventions.
DATA SOURCES: MEDLINE, Cochrane Library, and PsycINFO (January 1990 through September 2015); clinical trial registries; and reference lists.
STUDY SELECTION: English-language studies that enrolled employed adults and compared integrated interventions with usual work practice, no intervention, or another intervention.
DATA EXTRACTION: Dual abstraction and risk-of-bias (ROB) assessment.
DATA SYNTHESIS: Ten of the 15 included studies had high ROB, primarily because of selection and attrition bias. Findings graded as having low strength of evidence (SOE) supported the effectiveness of TWH interventions for improving smoking cessation, as measured by self-reported 7-day abstinence over 22 to 26 weeks (2 randomized, controlled trials [RCTs]; n = 737), and increasing consumption of fruits and vegetables over 26 to 104 weeks (3 RCTs; n = 6056); results apply to populations of blue-collar manufacturing and construction workers. Findings graded as having low SOE supported the effectiveness of TWH interventions for reducing sedentary work behavior in office workers over 16 to 52 weeks (2 RCTs; n = 262). Evidence was insufficient or lacking for other outcomes of interest, such as rates of work injuries, quality of life, and harms.
LIMITATION: Small, diverse body of evidence with many methodological limitations; possible publication bias.
CONCLUSION: Integrated TWH interventions might improve health behaviors (for example, reduce tobacco use and sedentary behavior and improve diet) of workers, but effects of these interventions on injuries and overall quality of life are not known.
PRIMARY FUNDING SOURCE: Agency for Healthcare Research and Quality
Physical Activity Promotion in the Evolving Work Landscape
How and where we do our work is changing in the United States across industry, government, and non-profit sectors. This evolving landscape includes downsized office space, the reduction of corporate fitness centers, decreased daily commutes, increased hybrid or remote work environments, and experiments with the length of the work week. While some of these changes may prove transient, others will likely be permanent changes affecting the context of work. Some occupations require in-person work settings, especially in the health care, education, travel and food processing sectors. Many of these employees are experiencing burnout after prolonged overtime work and stressful pandemic-related work conditions. Accordingly, employers are turning their focus to employee health and well-being; productivity, retention, promotion; diversity, equity, and inclusion; re-thinking their corporate wellness programs; and prioritizing financial stability, work-life balance, mental health, and other health-promoting culture, systems and policy changes
Effects of Changing Work Environments on Employer Support for Physical Activity During COVID-19
COVID-19 dramatically accelerated evolving changes in the way we define the “work environment” in the United States. In response to COVID-19, many employers have offered increased flexibility for where employees work, including remote (an employee’s workstation is at home) and hybrid work (an employee works both at the employer worksite and remotely, on predetermined schedules). Accordingly, worksite physical activity (PA) and sedentary behaviors (SB) such as extended sitting time (ST) may have changed.1,2 However, little is known about whether these work arrangements are associated with changes in employer support for PA. Interviews were conducted to assess this gap in understanding. Because little is known about employer support for equity with respect to PA and SB, this study sought to identify potential strategies to assure equity in PA opportunities across work environments
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