43 research outputs found
Fibroadenoma of the breast with florid epithelial cells hyperplasia: a case report
Fibroadenoma is a benign biphasic tumor of the breast, composed of an epithelial and a stroma component.
Fibroadenoma with epithelial cells hyperplasia may contribute to the higher risk of breast cancer, especially
for florid and atypical hyperplasia. The distinction between fibroadenoma with florid epithelial cells
hyperplasia, in-situ carcinoma and invasive duct carcinoma of the breast ban be difficult morphologically.
To solve the problem, immunohistochemical staining with specific andibodies will be helpfull in distinguishing
usual duct hyperplasia from ductal carcinoma in situ.
A case of fibroadenoma with florid epithelial cells hyperplasia has been reported. Morphologically, this
tumor is difficult to be differentiated from ductal carcinoma. Immunohistochemical staining with High
molecular weight cytokeratins 34BE12, Smooth Muscle Actin (SMA),E-cadherin could be used to determine the
diagnosis of this tumor
Trends in diagnosis and treatment of ductal carcinoma in situ of the breast in 403 cases over 1986–2002
Ductal carcinoma in situ of the breast in the Netherlands Cancer Institute. Outcome of 403 cases over the period 1986–2002
Squamous cell carcinoma in situ of the breast : a light microscopic and immunohistochemical study of a previously undescribed lesion.
Micrometastases in sentinel lymph nodes of patients with ductal carcinoma in situ of the breast should have no consequences for further treatment
Additional breast lesions in patients with breast cancer at MR imaging: impact on clinical management
Breast MR imaging in women at increased lifetime risk of breast cancer: clinical system for computerized assessment of breast lesions initial results.
Item does not contain fulltextThe authors developed a clinical system for computerized delineation, rating, and classification of breast lesions depicted in contrast material-enhanced magnetic resonance images obtained in women with increased lifetime risk of breast cancer. Initial results showed negative predictive values above 98% at 50% positive predictive value with negligible interoperator differences. The system demonstrated potential to help exclude malignancy with high confidence and reproducibility with a positive predictive value that is acceptable in screening
77. Optimal loco-regional control in larger breast cancer with modified radical mastectomy and selective use of adjuvant radiotherapy
[Diagnostics in clinically occult, radiologically suspect breast lesions more often surgery than needle diagnostics with image monitoring]
OBJECTIVE: To inventory the diagnostic methods used in patients with clinically occult, radiologically suspect breast lesions. DESIGN: Enquiry. METHOD: The departments of radiology of all Dutch hospitals were sent a list in January 2000 containing questions concerning the number of thread localizations in 1999 and the use of cytological or histological needle diagnostics with image monitoring prior to surgical intervention in clinically occult, radiologically suspect breast lesions. Of the 120 questionnaires mailed, 74 (62%) were completed and returned by clinics throughout the country. RESULTS: Fifty-one of the 74 hospitals (69%) had prior to operation carried out histological or cytological examinations and in these 51 hospitals this was done in 1743 of the 2857 lesions (61%): fine-needle aspiration cytology was performed in 1046 (/1743 = 60%; /4140 lesions in all 74 hospitals = 25%) and/or histological needle biopsy in 784 (45%; /4140 = 19%). CONCLUSION: In less than half of all non-palpable breast abnormalities non-surgical methods of diagnosis are used, histological needle biopsy less often than fine needle aspiration cytology