Managerial lead of an independent school refectory - allowance organization

Phylogeny of Forkhead (FOX) transcription factors. The FKH domain of forkhead proteins of H. sapiens, D. melanogaster, E. multilocularis, H. microstoma, and published FoxQ2 homologs from other animals were aligned, and a phylogeny was estimated by Maximum Likelihood analysis (with a JTT model) using MEGA 5.2 [85]. Bootstrap support values from 1,000 replicates are indicated next to the nodes. Nodes with lower than 50 % support were collapsed. GeneDB accession codes are given for E. multilocularis and H. microstoma and Genbank accession codes are given for all other sequences. The FoxQ2 group is outlined, and the foxQ2 genes of E. multilocularis and H. microstoma are indicated by arrows. (PDF 33 kb

Additional file 5: of Comparative analysis of Wnt expression identifies a highly conserved developmental transition in flatworms

Alkaline phosphatase-based development of whole-mount in situ hybridization in H. microstoma : Wnt2 and Wnt5. Bars: 50 Οm. (PDF 1653 kb

Pairwise comparison matrix for common somatic SNVs across all samples.

<p>In the table, the first number is the total number of common somatic SNVs while the second is the number of common protein-altering ones. The original numbers of somatic mutations and protein-altering ones for each sample are boxed (diagonal).</p><p>Pairwise comparison matrix for common somatic SNVs across all samples.</p

Somatic mutation patterns of primary, metastatic and PDX tumors.

<p>Proportion of somatic SNVs by class (C->A, C->G, C->T, T->A, T->C and T-G) in the primary, metastatic and PDX tumor samples are shown for the ten cancer samples included in this study.</p

Scatter plots of non-synonymous and non-sense mutations for (A) P042_PRI vs. P042_LIV and (B) P042_LIV vs. P042_LIV_PDX.

<p>The plots are based on the mutant allele frequencies (MAFs, from 0 to 1)) of non-synonymous and non-sense mutations from the paired samples. The mutations that are called in both samples are marked by green dots, while ones called in only one sample are colored blue. Gene names are shown for those key mutations discussed in the text.</p

Patient information.

<p>Patient information.</p

Summary of locations of somatic SNVs.

<p>Note: UTR, untranslated region; CDS, coding sequence.</p><p>Summary of locations of somatic SNVs.</p

Summary statistics of WES data.

<p>*For PDX samples, predicted mouse reads were excluded.</p><p>Summary statistics of WES data.</p

Somatic SNVs affecting key cancer genes.

<p>^$: from P047_PER</p><p>*: stop codon.</p><p>Somatic SNVs affecting key cancer genes.</p

Distribution of MAFs of protein-altering mutations identified in cancer samples.

<p>Each boxplot shows the MAFs (from 0 to 1) of somatic SNVs found in an individual sample along with the mean (the red horizontal line), SEM (standard error of the mean, shown a blue box) and SD (standard deviation, shown as a blue vertical line). PDX samples (MAFs in blue dots) in general show higher mean MAF values (close to 0.5) than those from tumor samples (MAFs in green dots), which indicates that the PDX samples were of much higher tumor purity since reads from mouse stromal cells were effectively removed from the original sequencing data.</p