The Effect of Motherhood on Wages and Wage Growth: Evidence for Australia

Labour market theory provides several reasons why mothers are likely to earn lower hourly wages than non-mothers. However, the size of any motherhood penalty is an empirical matter and the evidence for Australia is limited. This paper examines the effect of motherhood on Australian women’s wages and wage growth using a series of panel-data models which control for other relevant factors, both observed and unobserved. Using data from the Household, Income and Labour Dynamics in Australia (HILDA) survey, an unexplained motherhood wage penalty of around four per cent for one child, and eight per cent for two or more children, is found. Further analysis suggests that the wage penalty emerges over time through reduced wage growth, rather than through an immediate wage decline after the birth of a child. This reduction in wage growth is consistent with discrimination but also with a reduction in mothers’ work effort.Motherhood Wage Penalty, Wage Growth, Fixed Effects

Evaluating duration of response to treatment in systemic lupus erythematosus clinical trials.

ObjectiveTo evaluate response duration and identify predictors of transitioning into and out of the response state in patients with SLE receiving standard of care (SoC) in 52-week clinical trials.MethodsA multistate model (MSM) allowing for bidirectional transitions between response and non-response states was fit to data on 759 patients with SLE with active disease randomised to SoC. The probability of being in response at 52 weeks, average duration of response (sojourn time) and mean total time in response for SLE Responder Index (SRI-4, SRI-5, SRI-6) and BILAG-based Composite Lupus Assessment (BICLA) were estimated. Predictors of attainment and loss of SRI-5 response were also assessed.ResultsThe MSM estimated probability of being in response at 52 weeks ranged from 42% (SRI-6) to 61% (SRI-4). Mean duration of response ranged from 20.4 weeks (BICLA) to 31.5 weeks (SRI-4). Mean total time in response was 16.4-24.8 weeks. Baseline characteristics predictive of shorter SRI-5 response duration were African descent (p=0.005), longer history of disease (p=0.03), higher anti-dsDNA antibody titres (p=0.039), lower lymphocyte count (p=0.008) and lower haemoglobin (p=0.006). Younger age (p<0.001) and higher protein/creatinine ratio (p<0.001) were associated with higher likelihood of achieving SRI-5 but also shorter response duration.ConclusionFactors associated with disease severity were more predictive of shorter response duration than of 52-week response status. Analysing landmark response rates and response duration using MSM may be a more powerful way to distinguish effective investigational treatments from background SoC, although this remains to be evaluated in future trials

WORKPLACE RELIGIOUS ACCOMMODATION FOR MUSLIMS AND THE PROMISE OF STATE CONSTITUTIONALISM

This article considers whether state constitutionalism provides greater possibilities for workplace religious accommodation than is currently available to religious minorities within federal law under Title VII of the Civil Rights Act of 1964. We approach this question via a case study of the controversy over religious accommodation for practicing Muslims employed by the JBS Swift and Company meatpacking plant in Grand Island, N E. The case study consists of analyses of the requirements for religious accommodation under federal law, examination of the reasons why religious accommodation under federal law was not achieved in the Grand Island case, and analysis of Nebraska constitutional law on the subject of religious free exercise. We find that the language in the Nebraska Constitution regarding protection of religious practice provides grounds for Muslims and other religious minorities in Nebraska to seek religious accommodations in the workplace through state government venues that they have been unable to achieve under federal law

WORKPLACE RELIGIOUS ACCOMMODATION FOR MUSLIMS AND THE PROMISE OF STATE CONSTITUTIONALISM

This article considers whether state constitutionalism provides greater possibilities for workplace religious accommodation than is currently available to religious minorities within federal law under Title VII of the Civil Rights Act of 1964. We approach this question via a case study of the controversy over religious accommodation for practicing Muslims employed by the JBS Swift and Company meatpacking plant in Grand Island, N E. The case study consists of analyses of the requirements for religious accommodation under federal law, examination of the reasons why religious accommodation under federal law was not achieved in the Grand Island case, and analysis of Nebraska constitutional law on the subject of religious free exercise. We find that the language in the Nebraska Constitution regarding protection of religious practice provides grounds for Muslims and other religious minorities in Nebraska to seek religious accommodations in the workplace through state government venues that they have been unable to achieve under federal law

Lafora disease offers a unique window into neuronal glycogen metabolism

Lafora disease (LD) is a fatal, autosomal recessive, glycogen-storage disorder that manifests as severe epilepsy. LD results from mutations in the gene encoding either the glycogen phosphatase laforin or the E3 ubiquitin ligase malin. Individuals with LD develop cytoplasmic, aberrant glycogen inclusions in nearly all tissues that more closely resemble plant starch than human glycogen. This Minireview discusses the unique window into glycogen metabolism that LD research offers. It also highlights recent discoveries, including that glycogen contains covalently bound phosphate and that neurons synthesize glycogen and express both glycogen synthase and glycogen phosphorylase

“My universe is here”: implications for the future of academic libraries from the results of a survey of researchers

One of the major challenges of university libraries is to adequately support the information needs of researchers. This paper outlines the results of a survey conducted by Deakin University Library into the information needs of researchers and the library’s perceived role and performance. The survey consisted of twenty-three interviews conducted with researchers, and its results challenged established ideas regarding researchers’ preference for print, age of resources required, and reliance on specialist rather than general or cross-disciplinary databases. Of note were the decreasing physical use of the library, the increasing importance of online resources and the changing need for library support services. The study raises some key questions relating to the future of libraries and the role of librarians