Optics and Fluid Dynamics Department annual progress report for 2001

research within three scientific programmes: (1) laser systems and optical materials, (2) optical diagnostics and information processing and (3) plasma and fluid dynamics. The department has core competences in: optical sensors, optical materials, optical storage, biooptics, numerical modelling and information processing, non-linear dynamics and fusion plasma physics. The research is supported by several EU programmes, including EURATOM, by Danish research councils and by industry. A summary of the activities in 2001 is presented. ISBN 87-550-2993-0 (Internet

Optics and Fluid Dynamics Department annual progress report for 2002

research within three scientific programmes: (1) laser systems and optical materials, (2) optical diagnostics and information processing and (3) plasma and fluid dynamics. The department has core competences in: optical sensors, optical materials, optical storage, biophotonics, numerical modelling and information processing, non-linear dynamics and fusion plasma physics. The research is supported by several EU programmes, including EURATOM, by Danish research councils and by industry. A summary of the activities in 2002 is presented. ISBN 87-550-3197-8 (Internet

Mitochondria in parasitic plants

Plant mitochondrial genomes are renowned for their structural complexity, extreme variation in size and mutation rates, and ability to incorporate foreign DNA. Parasitic flowering plants are no exception, and the close association between parasite and host may even enhance the likelihood of horizontal gene transfer (HGT) between them. Recent studies on mistletoes (Viscum) have revealed that these parasites have lost an exceptional number of mitochondrial genes, including all complex I genes of the respiratory chain. At the same time, an altered respiratory pathway has been demonstrated. Here we review the current understanding of mitochondrial evolution in parasitic plants with a special emphasis on HGT to and from parasite mitochondrial genomes, as well as the uniquely altered mitochondria in Viscum and related plants. © 2020 The Author

High resection rates of colorectal liver metastases after standardized follow-up and multimodal management:an outcome study within the COLOFOL trial

Background: Outcome after colorectal liver metastases (CRLM) resection has improved over time, despite increased resection rates. Hence, it's crucial to identify all patients possible to treat with curative intent. The objectives of this study were to map recurrence pattern, treatment strategy and survival depending on treatment and follow-up strategy. Methods: In the COLOFOL-trial, patients with radically resected stage II-III colorectal cancer were randomized to high-frequency (6, 12, 18, 24 and 36 months; HF) or low-frequency (12 and 36 months; LF) follow-up. In this study, all CRLM within 5 years were identified and medical files scrutinized. Overall survival (OS) was analysed in uni- and multivariable analyses. Primary endpoint was 5-year OS. Results: Of 2442 patients, 235 (9.6%) developed metachronous CRLM of which 123 (52.3%) underwent treatment with curative intent, resulting in 5-year OS of 58%. Five-year OS for patients with CRLM was 43% after HF versus 24% after LF. The survival benefit was confirmed for HF 8 years from resection of the primary tumour, HR 0.63 (CI 0.46–0.85). Conclusion: A high proportion of metachronous CRLM was possible to treat with curative intent, yielding high survival rates. More intense follow-up after colorectal cancer resection might be of value in high-risk patients

Electrical characterization of single nanometer-wide Si fins in dense arrays

This paper demonstrates the development of a methodology using the micro four-point probe (μ4PP) technique to electrically characterize single nanometer-wide fins arranged in dense arrays. We show that through the concept of carefully controlling the electrical contact formation process, the electrical measurement can be confined to one individual fin although the used measurement electrodes physically contact more than one fin. We demonstrate that we can precisely measure the resistance of individual ca. 20 nm wide fins and that we can correlate the measured variations in fin resistance with variations in their nanometric width. Due to the demonstrated high precision of the technique, this opens the prospect for the use of μ4PP in electrical critical dimension metrology