Patient Survival Comparisons Between Peritoneal Dialysis and Hemodialysis

The choice between hemodialysis (HD) and peritoneal dialysis (PD) has been discussed for decades and outcomes have been compared inevitably between dialysis modalities. Many studies have been performed comparing costs of treatment, quality of life, and hospitalization and results have been variable. Most important and most controversial have been the studies that have attempted to compare patient survival on PD to that on HD. There is, however, still no final consensus on whether HD or PD treatment modality gives the best results. Consequently, both options have to be weighed in individual patients according to their specific needs, preferences, and clinical characteristics, with the aim of providing a patient-tailored kidney replacement therapy.</p

Patient Survival Comparisons Between Peritoneal Dialysis and Hemodialysis

The choice between hemodialysis (HD) and peritoneal dialysis (PD) has been discussed for decades and outcomes have been compared inevitably between dialysis modalities. Many studies have been performed comparing costs of treatment, quality of life, and hospitalization and results have been variable. Most important and most controversial have been the studies that have attempted to compare patient survival on PD to that on HD. There is, however, still no final consensus on whether HD or PD treatment modality gives the best results. Consequently, both options have to be weighed in individual patients according to their specific needs, preferences, and clinical characteristics, with the aim of providing a patient-tailored kidney replacement therapy.</p

To whom and why should I connect? Co-author Recommendation based on Powerful and Similar Peers

Sie, R. L. L., Drachsler, H., Bitter-Rijpkema, M., & Sloep, P. B. (2012). To whom and why should I connect? Co-author Recommendation based on Powerful and Similar Peers. International Journal of Technology Enhanced Learning (IJTEL), 4(1), 121-137. doi:10.1504/IJTEL.2012.048314The present article offers preliminary outcomes of a user study that investigated the acceptance of a recommender system that suggests future co- authors for scientific article writing. The recommendation approach is twofold: network information (betweenness centrality) and author (keyword) similarity are used to compute the utility of peers in a network of co-authors. Two sets of recommendations were provided to the participants: Set one focused on all candidate authors, including co-authors of a target user to strengthen current bonds and strive for acceptance of a certain research topic. Set two focused on solely new co-authors of a target user to foster creativity, excluding current co- authors. A small-scale evaluation suggests that the utility-based recommendation approach is promising, but to maximize outcome, we need to 1) compensate for researchers’ interests that change over time, and 2) account for multi-person co-authored papers

ERP effects of subject-verb agreement violations in patients with Broca's aphasia

Contains fulltext : 13805.pdf (publisher's version ) (Open Access)This article presents electrophysiological data on on-line syntactic processing during auditory sentence comprehension in patients with Broca's aphasia. Event-related brain potentials (ERPs) were recorded from the scalp while subjects listened to sentences that were either syntactically correct or contained violations of subject-verb agreement. Three groups of subjects were tested: Broca patients (n = 10), nonaphasic patients with a right-hemisphere (RH) lesion (n = 5), and healthy agedmatched controls (n = 12). The healthy, control subjects showed a P600/SPS effect as response to the agreement violations. The nonaphasic patients with an RH lesion showed essentially the same pattern. The overall group of Broca patients did not show this sensitivity. However, the sensitivity was modulated by the severity of the syntactic comprehension impairment. The largest deviation from the standard P600/SPS effect was found in the patients with the relatively more severe syntactic comprehension impairment. In addition, ERPs to tones in a classical tone oddball paradigm were also recorded. Similar to the normal control subjects and RH patients, the group of Broca patients showed a P300 effect in the tone oddball condition. This indicates that aphasia in itself does not lead to a general reduction in all cognitive ERP effects. It was concluded that deviations from the standard P600/SPS effect in the Broca patients reflected difficulties with on-line maintaining of number information across clausal boundaries for establishing subject-verb agreement

Sociomarkers of anhedonia in MDD

Background: Anhedonia is one of the two core symptoms of MDD, described as the decreased ability to experience pleasure in daily life. We aimed to describe anhedonia in everyday life of patients with Major Depressive Disorder (MDD), and investigate its link to social stress. We semi-randomly sampled anhedonia and social stress ten times a day, for seven consecutive days, by means of Experience Sampling Methods in the daily life of 53 MDD patients. Results: Multilevel analyses showed that anhedonia was less severe when patient were in company of others (versus being alone). Social stress was linked to anhedonia, both concurrently and prospectively. Albeit less strongly, anhedonia also prospectively predicted increases in social stress. Conclusions: Experiencing an increase in social stress makes it harder for depressed patients to experience pleasure in both current and future activities, suggesting that social stressors might put MDD patients at risk for the development of anhedonia

Factors that influence cooperation in networks for innovation and learning

Networked cooperation fails if the available partnerships remain opaque. A literature review and Delphi study uncovered the elements of a fruitful partnership. They relate to personality, diversity, cooperation, and management. Innovation networks and learning networks share the same cooperative intention, but they too often fail as members of the network do not know which partnerships are valuable. If one plans to build a support service that provides insight into the value of future cooperation, one first needs to know what contributes to effective and efficient cooperation. In addition to carrying out a literature review, we invoked the eDelphi method to answer this question. eDelphi is a method to solicit knowledge from experts anonymously and without geographical constraints. Observations from two eDelphi rounds are reported in this article. The first round focused on factor generation and determined which factors influence cooperation networks; it was conducted with two groups of six representative experts. Experts list open communication, a positive attitude, trust, keeping appointments, and personality as influential factors for cooperation networks. A team of four moderators categorised the factors in a second round, resulting in four core clusters: personal characteristics, diversity, effective cooperation, and managerial aspects. Interestingly the experts failed to list some factors that are mentioned in the literature. This finding is discussed

A new approach to collaborative creativity support of new product designers

Bitter-Rijpkema, M., Sloep, P. B., Sie, R., Van Rosmalen, P., Retalis, S., & Katsamani, M. (2011). A new approach to collaborative creativity support of new product designers. International Journal of Web Based Communities, 7(4), 478-492. DOI: 10.1504/IJWBC.2011.042992Effective collaborative creativity is crucial to contemporary professionals who have to continuously produce innovative products and services. The technological nature and complexity of the innovations require team work, among specialists from different disciplines. Often these teams work in a distributed fashion, across boundaries of time and place. Therefore they need electronic “spaces” that support (‘afford’) their creative collaboration. Co-creativity support is not only a matter of making appropriate groupware spaces available but also of providing concurrent support in all these dimensions. These considerations inspired the development of the idSpace platform. idSpace is a collaboration platform integrating a variety of creativity tools with pedagogy-based guidance. It aims to optimize both the use of creativity techniques themselves and of the supporting processes of team collaboration and knowledge creation. In this paper we zoom in on Knowledge-sharing Strategies for Collaborative Creativity (KS4CC). We show how collaborative creativity can be enhanced via integration of pattern-based pedagogical flow support, including suggestions of optimal use of creativity techniques. The KS4CC strategies consist of a merger of learning and collaboration flow patterns with support for the application of creative techniques