21 research outputs found

    Perfil de metilação diferencial em suínos normais e afetados com osteocondrose latens.

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    Reconstructing the Cryogenian–Ediacaran evolution of the Porongos fold and thrust belt, Southern Brasiliano Orogen, based on Zircon U–Pb–Hf–O isotopes

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    <p>The Neoproterozoic geotectonic triad of the Brasiliano Orogen is reconstructed in southern Brazil from studies focused on the Porongos fold and thrust belt. We integrate field geology with isotopic studies of zircon U–Pb SHRIMP and Lu–Hf–O laser determinations in seven metasedimentary and three metavolcanic rock samples. The results indicate that the Porongos palaeo-basin was derived from mixed sources (3200–550 Ma), with major contributions from Rhyacian (2170 Ma) and Ediacaran (608 Ma) sources. Minor contributions from Archaean to Tonian sources are also registered. The maximum depositional age of the Porongos palaeo-basin is established by the age range of 650–550 Ma with <i>T</i><sub>DM</sub> model ages between 2.5 and 1.3 Ga. The reworked signature (<i>Δ</i><sub>Hf</sub> values = −34 to −4) and the characteristic crustal magma reservoirs (<i>ÎŽ</i><sup>18</sup>O ≄5.3 ‰) indicate that these sediments are equivalent to Neoproterozoic granites of the Dom Feliciano Belt. The episodic depositional history started in the Cryogenian (650 Ma) and lasted until the Ediacaran (most likely 570 Ma). A magmatic event of Tonian age is recorded in rhyodacite samples interleaved with the metasedimentary rocks and dated at 773, 801, and 809 Ma. The crustal evolution of the Sul-Riograndense Shield included mountain building, folding and thrusting and flexural subsidence in the foreland. An orogenic triad is revealed as the Pelotas Batholith, the Porongos fold and thrust belt and the CamaquĂŁ Basin, all part of the Dom Feliciano Belt.</p

    Genome-wide association study for performance traits in chickens using genotype by sequencing approach.

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    Performance traits are economically important and are targets for selection in breeding programs, especially in the poultry industry. To identify regions on the chicken genome associated with performance traits, different genomic approaches have been applied in the last years. The aim of this study was the application of CornellGBS approach (134,528 SNPs generated from a PstI restriction enzyme) on Genome-Wide Association Studies (GWAS) in an outbred F2 chicken population. We have validated 91.7% of these 134,528 SNPs after imputation of missed genotypes. Out of those, 20 SNPs were associated with feed conversion, one was associated with body weight at 35 days of age (P < 7.86E-07) and 93 were suggestively associated with a variety of performance traits (P < 1.57E-05). The majority of these SNPs (86.2%) overlapped with previously mapped QTL for the same performance traits and some of the SNPs also showed novel potential QTL regions. The results obtained in this study suggests future searches for candidate genes and QTL refinements as well as potential use of the SNPs described here in breeding programs.Made available in DSpace on 2018-05-10T01:04:20Z (GMT). No. of bitstreams: 1 final8329.pdf: 936680 bytes, checksum: fc8d08dbae481f317ca915c4b191070a (MD5) Previous issue date: 2017-05-11bitstream/item/159737/1/final8329.pd

    Hegel penseur du droit

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    Les Principes de la philosophie du droit sont l'un des textes les plus lus et les plus controversĂ©s de Hegel. Il s’agit Ă  la fois d’un bilan de l’histoire de la philosophie morale, juridique et politique et d’une analyse audacieuse et « engagĂ©e » de la modernitĂ© post-rĂ©volutionnaire. Pourtant, malgrĂ© sa destination pĂ©dagogique et sa rĂ©daction soignĂ©e, le prĂ©cis de 1820 est d’un abord malaisĂ©, dans la mesure oĂč il ne se soustrait Ă  aucune des exigences de ce qui, pour Hegel, garantit la « scientificitĂ© » d’un traitĂ© de philosophie. Il n’y a rien d’étonnant, par consĂ©quent, au fait que les querelles d’interprĂ©tation les plus violentes aient eu lieu Ă  son propos et que la pensĂ©e hĂ©gĂ©lienne du droit ait, tour Ă  tour, servi de caution ou de repoussoir aux prises de position politiques les plus diverses. La difficultĂ© du texte mais aussi le caractĂšre stratĂ©gique des thĂšmes abordĂ©s font en effet des Principes de la philosophie du droit un idĂ©al miroir Ă  fantasmes. Or ce que l’on nomme la « fin des idĂ©ologies » ouvre la voie Ă  une lecture plus sereine (mais peut-ĂȘtre plus exigeante) de la conceptualisation hĂ©gĂ©lienne du droit et pas seulement de ce que Hegel nomme le « droit Ă©tatique », mais aussi du droit privĂ© (« abstrait »), centrĂ© sur la question de la propriĂ©tĂ©, et du droit qu'a l’individu de voir honorĂ©e sa qualitĂ© de sujet moral agissant. Ce recueil d’études, qui illustre les tendances actuelles de la recherche, propose une lecture Ă  la fois synthĂ©tique et dĂ©taillĂ©e de l’ouvrage de Hegel en insistant non seulement sur sa dimension « systĂ©matique » et spĂ©culative, mais aussi sur ses prises de position les plus novatrices. Il ne s’agit pas de prĂ©tendre que Hegel soit avant tout un philosophe du droit, encore moins de mettre entre parenthĂšses le puissant soubassement mĂ©taphysique ou spĂ©culatif de sa doctrine de l’esprit objectif, mais de rĂ©Ă©valuer ce moment du systĂšme et de tirer parti des appuis qu'il peut offrir Ă  la philosophie contemporaine
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