8 research outputs found

    El clima social escolar y su influencia en el rendimiento académico

    No full text
    Se centra en cuestiones relativas al clima social del aula como claro determinante del bienestar del alumno, que afecta tanto a su aprendizaje y rendimiento como a su desarrollo personal y social. La muestra utilizada es de 15 profesores y 532 alumnos de séptimo curso de EGB, procedentes de distintos centros estatales y concertados de Madrid y provincia. La hipótesis que se plantea es que existen diferencias significativas en la percepción que tienen del clima escolar los sujetos con alto y bajo rendimiento académico. A partir de una comprobación inicial hecha con una muestra reducida de escolares en la que se obtiene como resultado que el cociente intelectual de los sujetos no corresponde con las calificaciones otorgadas por su rendimiento real, correlaciona resultados obtenidos de cociente intelectual y la percepción que tienen los sujetos del ambiente de aprendizaje. Existen diferencias significativas en la percepción del clima social escolar en sujetos con alto y bajo rendimiento en algunas variables consideradas. Es conveniente hacer un reflexión crítica sobre el clima en el que se desarrolla el proceso enseñanza-aprendizaje, en cómo se percibe por el alumno y la relación ambiente vivenciado - rendimiento conseguido, y destacar aquellos aspectos psicopedagógicos que están en relación con dichas variables a fin de que contribuyan a mejorar el clima social del aula.MadridES

    Left atrial appendage occlusion with Amplatzer Cardio Plug is an acceptable therapeutic option for prevention of stroke recurrence in patients with non-valvular atrial fibrillation and contraindication or failure of oral anticoagulation with acenocumarol

    No full text
    ABSTRACT Left atrial appendage occlusion (LAAO) appears as a therapeutic option for some atrial fibrillation patients not suitable for oral anticoagulation because an increased hemorrhagic risk or recurrent ischemic events despite anticoagulant treatment. Methods Report of consecutive atrial fibrillation patients treated with LAAO with Amplatzer Cardio Plug because contraindication or failure of oral anticoagulation with acenocumarol. CHA2DS2VASC, HAS-BLED, NIHSS, mRS, procedural complications and outcome were assessed. Seven patients (73 ± 6 year-old) were treated after intracerebral (n = 5) and gastrointestinal (n = 1) hemorrhages or ischemic stroke recurrence while on acenocumarol (n = 1). Results Mean follow up was 18 months. Baseline CHA2DS2Vasc y HAS-BLED scores were 5.6 ± 0.7 and 4.1 ± 0.3 respectively. There were no strokes or deaths. There was only one non-serious adverse event. Conclusion LAAO with ACP appears as a feasible therapeutic option for stroke prevention in patients with atrial fibrillation and failure or contraindication to acenocumarol

    Overrepresentation of verbal repetition deficits in aphasic men with stroke: A systematic literature review and meta-analysis

    No full text
    Introduction: The arcuate fasciculus (AF) is a key component for language repetition Neuroimaging evidence indicates a gender-dimorphic architecture of this white matter tract. Strong left lateralization of the direct segment of the AF is m∼ore frequent in men ( 85%), while mild lateralization or symmetrical bilateral ∼ representation ( 60%) is more prevalent amongst women. Therefore, most men do not have a well-developed right AF. This predicts that men with aphasia and left hemisphere damage will have less capacity than aphasic women to compensate repetition deficits and, consequently, aphasias associated to repetition deficits (e.g conduction aphasia – CA) will be more prevalent in men. While this assumption is intuitively appealing, it has not been empirically tested up to now. Methods: A systematic review and meta-analysis of published cases of CA and transcortical aphasia (TA) was performed. Adult patients with first-ever unilateral cerebrovascular event and no prior history of neurological or psychiatric disease were included in the database. The men: women proportion of CA and TA was calculated from the database, and compared with the men:women proportion of stroke prevalence. The group of patients with aphasias showing relatively preserved repetition (transcortical motor and sensory aphasias) was used as control. Patients with mixed transcortical aphasia were excluded because repetition is not fully preserved. Results: Two hundred fifty three publications were included, gathering 799 cases of CA and TA. Males accounted for 74% (n = 375) of CA subjects (n = 507), while among TA (n=249, mixed TA excluded) men represented 62% (n=154) of subjects. Compared with 59% of male prevalence in stroke, men were overrepresented amongst CA (p<0.0001, 95% CI 68.91 to 76.82) in comparison with the control group (TA with exclusion of mixed TA, p= 0.2848, 95% CI 55.50 to 67.91). Discussion:Chronic repetition deficits are more prevalent in men than in women.This finding has important implications for the diagnosis and rehabilitation of aphasia in men, since verbal repetition is a major resource in language therapy. References: Catani M et al. PNSA (2007)104(43), 17163-17168. Berthier ML et al. Cortex (2012) 48, 133-143.Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech

    Argentinian initiative for the study of down syndrome and alzheimer's disease (IASDA)

    No full text
    Alzheimer's Disease (AD) is not only more frequent and has an earlier onset in Down Syndrome (DS) than in the general population, but also has an atypical clinical phenotype and an uncertain genetic risk factor and biomarker profile. The aim of this study is to investigate clinical, genetic and biomarker aspects of AD in DS.Fil: Pertierra, Lucía. Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia; ArgentinaFil: Surace, Ezequiel Ignacio. Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Tapajoz, Fernanda. Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia; ArgentinaFil: Magrath Guimet, Nahuel. Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia; ArgentinaFil: Bérgamo, Yanina. Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia; ArgentinaFil: Vázquez, Silvia. Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia; ArgentinaFil: Sevlever, Gustavo. Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia; ArgentinaFil: Allegri, Ricardo Francisco. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia; ArgentinaAlzheimer's Association International ConferenceLos AngelesEstados UnidosAlzheimer's Associatio

    Evaluation of Cerebrospinal Fluid Neurofilament Light Chain as a Routine Biomarker in a Memory Clinic

    No full text
    Systematic evaluation of biomarkers in representative populations is needed to validate their clinical utility. In this work, we assessed the diagnostic performance of cerebrospinal fluid (CSF) neurofilament light chain (NfL) in a neurocognitive clinical setting. A total of 51 patients with different cognitive clinical syndromes and 11 cognitively normal individuals were evaluated in a memory clinic in Argentina. Clinical conditions included mild cognitive impairment (MCI, n = 12), dementia of Alzheimer's type (DAT, n = 14), behavioral variant frontotemporal dementia (bvFTD, n = 13), and primary progressive aphasia (logopenic [n = 6], semantic [n = 2], and nonfluent [n = 4]). We quantified CSF NfL and core Alzheimer's disease biomarkers using commercially available ELISA kits. Cortical thickness was analyzed on brain magnetic resonance imaging scans from 10 controls and 10 patients. CSF NfL was significantly increased in MCI, FTD, and DAT patients compared with controls (Kruskal-Wallis, p <.0001). Interestingly, receiver operating characteristic curve analysis showed the highest area under the curve (AUC) value when analyzing control versus bvFTD patients (AUC = 0.9441). Also, we observed a marginally significant correlation between NfL levels and left orbitofrontal cortex thickness in a small group of patients with FTD. Overall, our results further support CSF NfL as a promising biomarker in the diagnostic workup of bvFTD.Fil: Niikado, Matías. Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Chrem Mendez, Patricio Alexis. Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia; ArgentinaFil: Itzcovich, Tatiana. Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia; ArgentinaFil: Barbieri Kennedy, Micaela. Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia; ArgentinaFil: Calandri, Ismael. Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia; ArgentinaFil: Martinetto, Horacio Enrique. Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Serra, Mercedes. Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia; ArgentinaFil: Calvar, Jorge. Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia; ArgentinaFil: Campos, Jorge. Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia; ArgentinaFil: Russo, María Julieta. Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia; ArgentinaFil: Pertierra, Lucía. Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia; ArgentinaFil: Allegri, Ricardo Francisco. Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Sevlever, Gustavo. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia; ArgentinaFil: Surace, Ezequiel Ignacio. Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentin

    Una clasificación biológica para la enfermedad de Alzheimer: amiloide, tau y neurodegeneración (A / T / N): resultados de la iniciativa de neuroimagen de la enfermedad de Alzheimer argentino

    No full text
    The aim of this study was to describe the A/T/N research framework classification for AD in the Argentine ADNI cohort and to explore the prediction to develop dementia in a prospective two-year follow-up.El objetivo de este estudio fue describir la clasificación del marco de investigación A / T / N para la enfermedad de Alzheimer en la cohorte ADNI argentina y explorar la predicción para desarrollar demencia en un seguimiento prospectivo de dos años
    corecore