Potere gestorio e circolazione dell'azienda

Nel titolo della presente indagine il tema della circolazione dell'azienda si collega a quello della gestione, che \ue8 momento o profilo dell'impresa; ed il riferimento al "potere" gestorio vale a problematizzare l'argomento, in qualche modo risolvendolo in una questione, o in un reticolo di questioni, cio\ue8 volgendolo in chiave di interrogativo. La circolazione dell'azienda appartiene al piano della gestione, \ue8 cio\ue8 un momento di esercizio dell'impresa, di guisa che pu\uf2 essere determinata ed attuata da chi appunto della gestione \ue8 incaricato? O risale piuttosto al piano delle determinazioni di fondo, di struttura, di selezione ed organizzazione dello stesso modello di impresa, di cui poi la gestione realizza l'esercizio

La cartolarizzazione dei crediti tributari degli enti locali: alcune questioni aperte

Nell\u2019ambito delle operazioni di cartolarizzazione aventi ad oggetto crediti della pubblica amministrazione, una delle questioni interpretative pi\uf9 delicate e tuttora aperte concerne la disciplina applicabile ai fini dell\u2019individuazione dei contraenti coinvolti, ed in particolare del soggetto incaricato di assumere la veste di societ\ue0 veicolo. Alla complessit\ue0 della questione non sembrerebbe, sino ad ora, essersi accompagnata un\u2019approfondita riflessione dottrinale e giurisprudenziale sul tema, nonostante le evidenti ricadute applicative allo stesso connesse. Le successive considerazioni, pur riferite al limitato ambito della cartolarizzazione dei crediti tributari degli enti locali, scaturiscono dal tentativo di affrontare il problema in chiave sistematica, nell\u2019ambito del pi\uf9 generale quadro normativo in materia di appalti pubblici, oltre che della disciplina della cartolarizzazione dei credit

World Health Organization (WHO)/International Society of Urological Pathology (ISUP) grading in fine‐needle aspiration biopsies of renal masses

Background Utilization of fine‐needle aspiration (FNA) biopsy for the evaluation of renal masses has been increasing at our institution. At times diagnostic material on direct smears is superior to that in the cell block/core biopsy, therefore assigning an accurate nuclear grade in the cytopathology report would provide useful prognostic information. Methods Search of the pathology database identified renal FNAs performed during an 11‐year period (2006–2017). Corresponding core biopsies and resections were identified. Cases with a diagnosis of primary renal neoplasia on FNA, core biopsy, and/or resection were included. Two pathologists reviewed all cases and assigned a World Health Organization (WHO)/International Society of Urological Pathology (ISUP) grade to each FNA, core biopsy, and resection case. Results A total of 162 kidney FNAs were identified. Primary renal neoplasia was diagnosed in 137 cases on core biopsy/resection. Among diagnostic FNAs of clear cell RCC and papillary RCC with core biopsy/resection specimens for re‐review (n = 52), reviewers assigned a concordant WHO/ISUP grade to 83% (43/52) of cases. Among 9 cases with discrepant scores, all had a discrepancy of 1 grade and were undergraded on FNA. Using a two tier grading system (low vs. high grade), reviewers assigned a concordant grade to 88% (46/52) of cases. Among 6 cases with discrepant scores, all were classified as low grade (WHO/ISUP grade 2) on FNA versus high grade (WHO/ISUP grade 3) on resection. Conclusion The WHO/ISUP grade assigned on FNA shows good concordance with subsequent resection/core specimens (83%), with all discrepant cases being undergraded by one grade

Oxidative potential associated with urban aerosol deposited into the respiratory system and relevant elemental and ionic fraction contributions

Size-segregated aerosol measurements were carried out at an urban and at an industrial site. Soluble and insoluble fractions of elements and inorganic ions were determined. Oxidative potential (OP) was assessed on the soluble fraction of Particulate Matter (PM) by ascorbic acid (AA), dichlorofluorescein (DCFH) and dithiothreitol (DTT) assays. Size resolved elemental, ion and OP doses in the head (H), tracheobronchial (TB) and alveolar (Al) regions were estimated using the Multiple-Path Particle Dosimetry (MPPD) model. The total aerosol respiratory doses due to brake and soil resuspension emissions were higher at the urban than at the industrial site. On the contrary, the doses of anthropic combustion tracers were generally higher at the industrial site. In general, the insoluble fraction was more abundantly distributed in the coarse than in the fine mode and vice versa for the soluble fraction. Consequently, for the latter, the percent of the total respiratory dose deposited in TB and Al regions increased. Oxidative potential assay (OPAA) doses were distributed in the coarse region; therefore, their major contribution was in the H region. The contribution in the TB and Al regions increased for OPDTT and OPDCFH

Recensione a G.Guizzi, Il «caso Balzac». Storie di diritto e letteratura

Recensione al libro di Giuseppe Guizzi dal titolo Il «caso Balzac». Storie di diritto e letteratura, Il Mulino, 2020, ripercorrendone lo svolgimento ripartito per macrosettori del diritto privato patrimoniale – il diritto dei contratti, delle successioni, dell’intermediazione finanziaria, dell’iniziativa economica e della concorrenza, dell’insolvenza e del fallimento, del mercato bancario e mobiliare, il diritto processuale civile e i meccanismi di risoluzione negoziata delle controversie per via di transazione – in contrappunto con le opere e i personaggi fondamentali di Balzac

Recensione a G.Terranova, Il ragionamento giuridico

Recensione al libro di Giuseppe Terranova, Il ragionamento giuridico, Giuffrè Lefebvre, 202

Quantitative Characterization of α-Synuclein Aggregation in Living Cells through Automated Microfluidics Feedback Control

Aggregation of α-synuclein and formation of inclusions are hallmarks of Parkinson's disease (PD). Aggregate formation is affected by cellular environment, but it has been studied almost exclusively in cell-free systems. We quantitatively analyzed α-synuclein inclusion formation and clearance in a yeast cell model of PD expressing either wild-type (WT) α-synuclein or the disease-associated A53T mutant from the galactose (Gal)-inducible promoter. A computer-controlled microfluidics device regulated α-synuclein in cells by means of closed-loop feedback control. We demonstrated that inclusion formation is strictly concentration dependent and that the aggregation threshold of the A53T mutant is about half of the WT α-synuclein (56%). We chemically modulated the proteasomal and autophagic pathways and demonstrated that autophagy is the main determinant of A53T α-synuclein inclusions’ clearance. In addition to proposing a technology to overcome current limitations in dynamically regulating protein expression levels, our results contribute to the biology of PD and have relevance for therapeutic applications

ATLAS RPC Quality Assurance results at INFN Lecce

The main results of the quality assurance tests performed on the Resistive Plate Chamber used by the ATLAS experiment at LHC as muon trigger chambers are reported and discussed. Since July 2004, about 270 RPC units has been certified at INFN Lecce site and delivered to CERN, for being integrated in the final muon station of the ATLAS barrel region. We show the key RPC characteristics which qualify the performance of this detector technology as muon trigger chamber in the harsh LHC enviroments. These are dark current, chamber efficiency, noise rate, gas volume tomography, and gas leakage.Comment: Comments: 6 pages, 1 table, 9 figures Proceedings of XXV Physics in Collision-Prague, Czech Republic, 6-9 July 200