3,017 research outputs found

    An Assessment of Health Disparities among a Community Sample of LGBQ College Students

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    Lesbian, gay, bisexual, and queer (LGBQ) individuals are a marginalized population in the United States, and this status places them at a greater risk for adverse health outcomes, such as tobacco and substance use, obesity, cancer, sexually-transmitted infections, violence, mental health issues, and suicide. The present study used individual- and microsystem-level data from the American College Health Association (ACHA)-National College Health Assessment (NCHA) to compose a risk assessment for LGBQ students at a mid-Atlantic university. The study incorporated various levels of the ecological social model in an analysis of potentially influential factors on the development of LGBQ health disparities. 856 participants completed a self-administered anonymous survey that included questions assessing a broad variety of health indicators, such as alcohol, tobacco, and other substance use, sexual health, mental health, nutrition, and personal safety and violence. A significant minority of the sample identified with a sexual orientation other than heterosexual (n=184, 21.6%). Sexual minority students reported significantly higher rates of various types of substance use [e.g., sedatives x2 (1,N=856)=3.543,

    Réminiscences ferroviaires d'il y a un siècle

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    Super-resolution imaging within reach

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    Although several optical techniques have been recently developed in order to overcome the resolution limit in microscopy, the imaging of sub-wavelength features is still a real challenge. In practise, super-resolution techniques remain difficult to build or are photo-toxic for the biological samples. However, microsphere-assisted microscopy has recently made super-resolution imaging accessible to scientists (e.g. optical metrologists, engineers and biologists). This paper presents an easy-to-implement optical setup to perform full-field and contactless super-resolution measurements of nanostructured media or biological elements. For this purpose, a classical microscope was enhanced by introducing a transparent microsphere. We show that this rather simple approach makes it possible to achieve a lateral resolution of 200 nm in air, i.e. the visualization of feature sizes of 100 nm

    Rape and Posttraumatic Stress Disorder (PTSD): Examining the Mediating Role of Explicit Sex-Power Beliefs for Men Versus Women

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    Many rape survivors exhibit symptoms of post-traumatic stress disorder (PTSD), and recent literature suggests survivors\u27 beliefs about sex and control may affect PTSD symptoms. The present study examined beliefs about sex and power as potential mediators of the relationship between rape and PTSD symptoms for men versus women. Participants (N = 782) reported lifetime history of rape, current PTSD symptoms, and beliefs about sex and power. Women reported higher levels of lifetime history of rape than men (19.7% for women; 9.7% for men). While rape history predicted PTSD symptoms for both genders, beliefs about sex and power were shown to be a significant partial mediator of this relationship for men, but not for women. Results extend the literature on rape and PTSD by suggesting that survivors\u27 beliefs about sex and power are connected and can affect their PTSD symptoms. Additionally, results illustrate how sexual violence against men may reaffirm male gender roles that entail power and aggression, and ultimately affect trauma recovery

    Agile low phase noise radio-frequency sine wave generator applied to experiments on ultracold atoms

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    We report on the frequency performance of a low cost (~500$) radio-frequency sine wave generator, using direct digital synthesis (DDS) and a field-programmable gate array (FPGA). The output frequency of the device may be changed dynamically to any arbitrary value ranging from DC to 10 MHz without any phase slip. Sampling effects are substantially reduced by a high sample rate, up to 1 MHz, and by a large memory length, more than 2.10^5 samples. By using a low noise external oscillator to clock the DDS, we demonstrate a phase noise as low as that of the master clock, that is at the level of -113 dB.rad^2/Hz at 1 Hz from the carrier for an output frequency of 3.75 MHz. The device is successfully used to confine an ultracold atomic cloud of rubidium 87 in a RF-based trap, and there is no extra heating from the RF source.Comment: 10 pages, 6 figure

    Variation of prostate-specific antigen value in men and risk of high-grade prostate vancer : analysis of the prostate, lung, colorectal, and ovarian cancer screening trial study

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    To investigate variations in prostate-specific antigen (PSA) levels among men with an initial normal PSA level in the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial study. Data were extracted from the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial study data set on all men in the interventional arm, with 2 tests performed in a period of < 2 years and with an initial result of the first test <4 ng/mL. The range of variation between first and second tests was computed. Risks of cancer stratified on Gleason score were computed using logistic regression. A total of 31,286 men had 2 PSA tests within 2 years and with an initial value < 4 ng/mL. From the first to the second test, the median variation of PSA levels was 3.4% (interquartile range, -15% to +26%). The variation in PSA value was not associated with the delay between the first and the second test (P = .36), age (P = .16), body mass index (P = .41), and race (P = .12). A total of 2,781 prostate cancers were diagnosed during follow-up. Adjusting for age and initial PSA level, the risk of prostate cancer increased linearly with increasing PSA level at the second test, with an odds ratio of 1.079 (95% confidence interval, 1.058-1.101) for each percent increase in PSA level. However, the variation in PSA was not associated with a higher Gleason score (P = .95 for level variations in cancer of Gleason score < 7 vs ≥ 7). Although an increase in PSA level over time is associated with increased risk of prostate cancer, this association is not related to more aggressive tumors

    Is Helping Really Helping? Health-Related Quality of Life after TBI Predicting Caregiver Depression Longitudinally in Latin America

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    Objective: Studies have shown that functional and psychosocial sequelae of traumatic brain injury (TBI) predict emotional well-being of caregivers (Harris, 2000). Previous research examining the mental health of caregivers and the health-related quality of life (HRQoL) of people with TBI have primarily been in the US (Sander, 2012). Very little research has been conducted to uncover the unique relationships between HRQoL of people with TBI and caregiver mental health longitudinally, or in low-middle income Latin American countries. The aim of this study was to evaluate how HRQoL after TBI predict caregiver depression longitudinally in two countries and three data collection sites in Latin America. Design: Multi-site, multinational longitudinal study. Setting: Three hospitals in Neiva and Cali, Colombia, and Mexico City, Mexico (before hospital discharge), as well as in the homes of individuals with TBI and caregivers in these regions (before discharge, at 2 and 4 months after discharge). Participants: A sample of 109 TBI caregiver-patient dyads (n = 218) was included in the study. Main Outcome Measure(s): Caregiver depression (Patient Health Questionnaire-9) and HRQoL in the person with TBI (Short Form-36). Results: Three multiple regressions were conducted to examine which aspects of patient HRQoL at baseline predicted caregiver depression at baseline, 2 months, and 4 months post-discharge. Eight aspects of patient HRQoL were simultaneously entered into each model as predictors: physical functioning, role limitations (physical and emotional), vitality, mental health, social functioning, pain, and general health. At baseline, the overall model significantly predicted caregiver depression, F(8, 105) = 2.62, p = .012, R 2 = .18. Patient mental health was the only significant unique predictor of caregiver depression at baseline, p = .021, β = -.34. The overall model predicting 2-month caregiver depression was significant, F(8, 101) = 3.21, p = .003, R 2 = .22. Only mental health, p = .016, β = -.36, was a significant unique predictor. The overall model predicting 4-month caregiver depression was significant, F(8, 98) = 2.70, p = .010, R 2 = .19, and no factors uniquely predicted caregiver depression, all ps\u3e.05. Conclusions: Results suggest that TBI patient HRQoL can predict caregiver depression among Latin American caregivers before and during the first 4 months after hospital discharge. Across all three time points (baseline, 2 months, and 4 months), caregiver depression was significantly predicted by patient HRQoL. At baseline, patient mental health was the only domain that uniquely predicted caregiver depression. At 2 months, only physical role limitations uniquely predicted caregiver depression, and no unique predictors were detected at 4 months. These findings suggest that within the cultural framework in Latin America, there is a strong relationship between functional and psychological impairments after TBI and depression outcomes in Latin American caregivers. The results highlight the importance of uncovering these relational distinctions and may infer early detection of mental health needs and psychological intervention considerations for Latin American caregivers.https://scholarscompass.vcu.edu/gradposters/1052/thumbnail.jp

    Variability of attitudes toward early initiation of HAART for HIV infection : a study of French prescribing physicians

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    This study assessed prescribing physicians' attitudes toward early initiation of HAART, three months after the dissemination of the first French official treatment guideline. Telephone interviews have been made in a national random sample of physicians with full- or part-time practice in hospital departments delivering care for HIV-infected patients. Questionnaires included hypothetical clinical cases. Logistic regression compared characteristics of respondents according to attitudes toward HAART. Among the 483 respondents (response rate = 87.0%), agreement was high with official recommendations to systematically initiate HAART with protease inhibitors (PIs) for patients with CD4+ cell counts &lt; or = 300/mm3, following a diagnosis of acute primary HIV infection, or for HIV sexual risk post-exposure prophylaxis. Confronted with a case of a naive asymptomatic patient with stable 450 CD4+/mm3, 34.6% would prescribe HAART with PIs in any case, and 29.8% only if the patient has plasma viral load &lt; or = 10,000 HIV RNA copies/ml. The remaining 35.6% would not prescribe PIs and were older, had limited activity in HIV care and expressed more interest in alternative medicines. To avoid a confusing impact of variability of clinical attitudes toward uncertainties associated with antiretroviral treatments among HIV-infected patients, shared decision-making between patient and physician should be promoted for initiation of HAART. [Authors]]]> Antiretroviral Therapy, Highly Active ; Attitude of Health Personnel ; HIV Infections ; Physician's Practice Patterns oai:serval.unil.ch:BIB_63B3A6A350EB 2022-05-07T01:19:14Z <oai_dc:dc xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:xs="http://www.w3.org/2001/XMLSchema" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd"> https://serval.unil.ch/notice/serval:BIB_63B3A6A350EB Logopenic syndrome and corticobasal dysfunction in a "benign" type 3 familial cortical myoclonic tremor with epilepsy. info:doi:10.1016/j.seizure.2015.01.004 info:eu-repo/semantics/altIdentifier/doi/10.1016/j.seizure.2015.01.004 info:eu-repo/semantics/altIdentifier/pmid/25645643 Magnin, E. info:eu-repo/semantics/article article 2015 Seizure, vol. 25, pp. 84-86 info:eu-repo/semantics/altIdentifier/eissn/1532-2688 urn:issn:1059-1311 eng oai:serval.unil.ch:BIB_63B3CEEF0A46 2022-05-07T01:19:14Z openaire documents urnserval <oai_dc:dc xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:xs="http://www.w3.org/2001/XMLSchema" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd"> https://serval.unil.ch/notice/serval:BIB_63B3CEEF0A46 Guidelines zur Behandlung von Aphasien. Schweizerische Aerztezeitung Aphasie, Suisse info:eu-repo/semantics/article article 2005 Bulletin des Médecins Suisses = Schweizerische Ärztezeitung, vol. 86, no. 40, pp. 2290-2297 urn:issn:1424-4012 ger https://serval.unil.ch/resource/serval:BIB_63B3CEEF0A46.P001/REF.pdf http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_63B3CEEF0A466 info:eu-repo/semantics/altIdentifier/urn/urn:nbn:ch:serval-BIB_63B3CEEF0A466 info:eu-repo/semantics/submittedVersion info:eu-repo/semantics/openAccess Copying allowed only for non-profit organizations https://serval.unil.ch/disclaimer application/pdf oai:serval.unil.ch:BIB_63B487FEFFA8 2022-05-07T01:19:14Z openaire documents urnserval <oai_dc:dc xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:xs="http://www.w3.org/2001/XMLSchema" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd"> https://serval.unil.ch/notice/serval:BIB_63B487FEFFA8 Preliminary results on the postmortem measurement of 3-beta-hydroxybutyrate in liver homogenates. info:doi:10.1007/s00414-013-0870-3 info:eu-repo/semantics/altIdentifier/doi/10.1007/s00414-013-0870-3 info:eu-repo/semantics/altIdentifier/pmid/23722498 Palmiere, C. Mangin, P. Werner, D. info:eu-repo/semantics/article article 2013 International Journal of Legal Medicine, vol. 127, no. 5, pp. 943-949 info:eu-repo/semantics/altIdentifier/eissn/1437-1596 urn:issn:0937-9827 <![CDATA[The concentrations of 3-beta-hydroxybutyrate (3HB) in blood and two liver samples were retrospectively examined in a series of medicolegal autopsies. These cases included diabetic ketoacidosis, nondiabetic individuals presenting moderate to severe decompositional changes and nondiabetic medicolegal cases privy of decompositional changes. 3HB concentrations in liver sample homogenates correlate well with blood values in all examined groups. Additionally, decompositional changes were not associated with increases in blood and liver 3HB levels. These results suggest that 3HB can be reliably measured in liver homogenates when blood is not available at autopsy. Furthermore, they suggest that metabolic disturbances potentially leading or contributing to death may be objectified through liver 3HB determination even in decomposed bodies

    Family Dynamics and Personal Strengths among Dementia Caregivers in Argentina

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    This study examined whether healthier family dynamics were associated with higher personal strengths of resilience, sense of coherence, and optimism among dementia caregivers in Argentina. Caregivers are usually required to assist individuals with dementia, and family members have typically fulfilled that role. Personal strengths such as resilience, sense of coherence, and optimism have been shown to protect caregivers from some of the negative experiences of providing care, though the family-related variables associated with these personal strengths are largely unknown. Hierarchical multiple regressions investigated the extent to which family dynamics variables are associated with each of the caregiver personal strengths after controlling for demographic and caregiver characteristics. A sample of 105 caregivers from Argentina completed a set of questionnaires during a neurologist visit. Family dynamics explained 32% of the variance in resilience and 39% of the variance in sense of coherence. Greater family empathy and decreased family problems were uniquely associated with higher resilience. Greater communication and decreased family problems were uniquely associated with higher sense of coherence. Optimism was not found to be significantly associated with family dynamics. These results suggest that caregiver intervention research focused on the family may help improve caregiver personal strengths in Argentina and other Latin American countries
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