Using the Sound Card as a Timer

Experiments in mechanics can often be timed by the sounds they produce. In such cases, digital audio recordings provide a simple way of measuring time intervals with an accuracy comparable to that of photogate timers. We illustrate this with an experiment in the physics of sports: to measure the speed of a hard-kicked soccer ball.Comment: 3 pages, 4 figures, Late

Large scale Optimal Transportation Meshfree (OTM) Simulations of Hypervelocity Impact

Large scale three-dimensional numerical simulations of hypervelocity impact of Aluminum alloy 6061-T6 plates by Nylon 6/6 cylindrical projectile have been performed using the Optimal Transportation Meshfree (OTM) method of Li et al. [7] along with the seizing contact and variational material point failure algorithm [17, 18]. The dynamic response of the Al6061-T6 plate including phase transition in the high strain rate, high pressure and high temperature regime expected in our numerical analysis is described by the use of a variational thermomechanical coupling constitutive model with SESAME equation of state, rate-dependent J2 plasticity with power law hardening and thermal softening and temperature dependent Newtonian viscosity. A polytropic type of equation of state fit to in-house ReaxFF calculations is employed to model the Nylon 6/6 projectile under extreme conditions. The evaluation of the performance of the numerical model takes the form of a conventional validation analysis. In support of the analysis, we have conducted experiments over a range of plate thicknesses of [0.5, 3.0] mm, a range of impact velocities of [5.0, 7.0]km/s and a range of obliquities of [0, 70]° at Caltech's Small Particle Hypervelocity Range (SPHIR) Facility. Large scale three-dimensional OTM simulations of hypervelocity impact are performed on departmental class systems using a dynamic load balancing MPI/PThreads parallel implementation of the OTM method. We find excellent full field agreement between measured and computed perforation areas, debris cloud and temperature field

Self-Validating Thermocouple

Self-Validating Thermocouple (SVT) Systems capable of detecting sensor probe open circuits, short circuits, and unnoticeable faults such as a probe debonding and probe degradation are useful in the measurement of temperatures. SVT Systems provide such capabilities by incorporating a heating or excitation element into the measuring junction of the thermocouple. By heating the measuring junction and observing the decay time for the detected DC voltage signal, it is possible to indicate whether the thermocouple is bonded or debonded. A change in the thermal transfer function of the thermocouple system causes a change in the rise and decay times of the thermocouple output. Incorporation of the excitation element does not interfere with normal thermocouple operation, thus further allowing traditional validation procedures as well

Physics Based Model for Cryogenic Chilldown and Loading. Part III: Correlations

In this report we discuss the details of the correlations used to recognize flow patterns and predict frictional losses, heat and mass transfer in the cryogenic two phase flow. The emphasis are put on the formulation of the correlation problem in terms of concise parametric and functional spaces allowing for efficient online search of the model parameters and accurate prediction of the phenomena observed during cryogenic loading. A special attention is paid to the discussion of the correlation dependence on the gravity. In this context the physics of stability, friction, and boiling in the two-phase flow that underlies the required correlations is discussed

Climate, geographic distribution and viviparity in Liolaemus (Reptilia; Squamata) species: when hypotheses need to be tested

La distribución de los reptiles, dada su dependencia de la temperatura, puede verse restringida en función del clima. En particular, se han planteado tres hipótesis que vinculan el clima con la distribución y el viviparismo en las especies de reptiles: i) hipótesis de clima variable, ii) hipótesis del clima frío e iii) hipótesis de manipulación materna. Entre las lagartijas de Sudamérica las especies del género Liolaemus se distribuyen tanto en ambientes cálidos como fríos y más del 50 % de ellas son vivíparas. En este trabajo estudiamos 47 especies de Liolaemus, tomando datos climáticos de sus sitios de colecta, su temperatura de preferencia (Tpref), el coeficiente de variación de la misma (CV) y los límites de tolerancia térmica (TT). Nuestros resultados no apoyan la hipótesis de clima variable, aunque ésta ha sido sustentada en estudios anteriores. Se encontró relación entre viviparismo y altitud, pero no entre viviparismo y las variables térmicas ambientales. Finalmente, las especies vivíparas de Liolaemus mostraron un comportamiento termorregulador más preciso que las especies ovíparas, reforzando la hipótesis de manipulación materna.Reptile’ distributions, under the light of their strong dependence on particular temperature requirements, may be constrained as a consequence of climate. The relationship between reptile viviparity and climate yielded two previously proposed hypotheses (the cold climate and the maternal manipulation hypotheses) that together with the climatic variability hypothesis; theoretically link climate, distribution and reproductive mode. The extensive variation in mean environmental temperature associated with changes in parity strategies has received much attention in this ectothermic group. Among Southamerican lizards, Liolaemus are distributed in cold and warm regions and more than 50 % of described species are viviparous. We studied 47 Liolaemus species considering climatic data where collected, preferred body temperature, its coefficient of variation and their thermal tolerance. Our results do not support the climate variability hypothesis, previously supported in other studies. We found a relationship between viviparity and elevation, but not between viviparity and thermal climatic variables. Finally, viviparous Liolaemus species showed more precise thermoregulatory behavior than oviparous ones, supporting the maternal manipulation hypothesis.Agencia Nacional de Promoción Científica y Tecnológica de Argentina (PICT 06-01205) y Consejo Nacional de Investigaciones científicas y Tecnológicas (PIP 2846 y PIP 6287)

Focus on the use of resveratrol in bladder cancer

Bladder cancer is the most common tumor of the urinary system, with a high incidence in the male population. Surgery and intravesical instillations can eradicate it, although recurrences are very common, with possible progression. For this reason, adjuvant therapy should be considered in all patients. Resveratrol displays a biphasic dose response both in vitro and in vivo (intravesical application) with an antiproliferative effect at high concentrations and antiangiogenic action in vivo (intraperitoneal application) at a low concentration, suggesting a potential role for it in clinical management as an adjuvant to conventional therapy. In this review, we examine the standard therapeutical approach to bladder cancer and the preclinical studies that have investigated resveratrol in xenotransplantation models of bladder cancer. Molecular signals are also discussed, with a particular focus on the STAT3 pathway and angiogenic growth factor modulation