The Advantages of Implant Therapy in Management of Edentulous jaws - Case Report

Potpuna proteza često nema zadovoljavajuću stabilnost u usnoj šupljini. Osobito nakon više godina nošenja proteze nastaju promjene u međučeljusnim odnosima te posljedično gubitak alveolarne kosti i poremećaj u stabilizaciji proteze. Postoji više načina implantološko-protetske rehabilitacije potpune bezubosti. U radu prikazujemo uporabu 2 usadka u bezuboj čeljusti te protetsku rehabilitaciju s tzv. kuglama. Prednosti ovakva načina implantološko-protetske rehabilitacije jesu u razmjerno lakom postavljanju usadka, postizanju zadovoljavajuće stabilnosti proteze te financijski razmjerno povoljnom rješavanju problema stabilnosti u odnosu prema drugim implantološkim metodama.Long term use of a conventional denture typically results in advanced alveolar bone loss, following a decrease of intermaxillary space and lack of stability. There a few ways in implant prosthodontics treatment of completely edentulous jaws. In this case report we show the use of two implants in completely endentulous patients and prosthetic rehabilitation with snap attachment. The advantages of implant prostodontics are relatively easily placement into the bone, stable implant assisted overlay denture, and relatively acceptable price

Kvazistacionarni pristup za analizu mikrotalasnih vodova

Analysis of microwave transmission lines is the main subject of research in the world for more than six decades. Since the day of stripline invention, back in 1949, and its modifications that followed in the forthcoming years, an "army" of scientists was trying to analyze it, simplify it and design new structures. These structures, due to their characteristics, have found wide application in microwave integrated circuits, for microwave filters and antennas design, delay lines, directional couplers, etc. Various numerical and analytical methods such as: the variational method, the method of moments, the boundary element method, the conformal mapping, the moving perfect electric wall method, the equivalent electrodes method etc. can be applied with more or less accuracy to the microwave transmission lines analysis. The aim of this doctoral dissertation is quasi TEM analysis of microwave transmission lines using the hybrid boundary method (HBEM). This method, developed at the Department of Theoretical Electrical Engineering in the Faculty of Electronic Engineering of Niš, is based on the equivalent electrodes methods and the point-matching method for the potential of the perfect electric conductor electrodes and for normal component of the electric field at the boundary surface between any two dielectric layers. Until now, it was applied to multilayered electromagnetic problems, grounding systems, electromagnetic field determination in the vicinity of cable terminations as well as magnetic field and force calculations of permanent magnets. In order to expand the field of method’s application, it is, for the first time, applied for the microwave transmission lines analysis. Single and coupled, shielded and open microwave transmission lines with homogeneous, isotropic single-layer and multilayer dielectrics were analysed in the examples presented. Structures with the ground planes of infinite width, but also the real cases – geometry with ground planes of finite width, the finite metallization thickness and substrate width, are also shown in this dissertation. The hybrid boundary element method has been proved to be a very simple, powerful and accurate procedure for microwave transmission lines analysis. The obtained system of linear equations is always well-conditioned, as the system matrix always has the greatest elements on the main diagonal. Quite good convergence for the desired parameters is achieved for only 700-1500 unknowns (equivalent electrodes). For the most examples, the convergence of results, calculation time, equipotential contours and distribution of polarized charges per unit length along boundary surfaces are shown in the tables and graphically. In order to validate the characteristic parameters results, obtained by the hybrid boundary element method, all the results will be compared to those obtained by software FEMM and FlexPDE as well as the results already reported in the literature. These results were shown in tables and graphically. The relative error for the characteristic impedance is less than 0.5 % in regards to the results obtained using the FEMM with few thousands elements and the uniform meshing technique. The computation time is even several times shorter than in the case of the analysis using the FEMM and FlexPDE. The real challenge for the author was to apply the hybrid boundary element method for analysis of microstrip transmission lines with Tellegen material (non-reciprocal bi-isotropic media). Unlike a wide range of literature that deals with the analysis of microwave transmission lines with isotropic dielectric, bi-isotropic media, due to their complexity, are not so common subject of research. The hybrid boundary element method was successfully applied for the analysis of such structures. Applying the hybrid boundary element method it is possible to analyze quickly, easily and sufficiently accurate the complex configuration of microwave transmission lines with isotropic and bi-isotropic substrate. In that way this dissertation represents a small contribution to the history of the development of methods for the analysis of microwave lines long more than 60 years

MAGE-A3/4 and NY-ESO-1 antigens expression in metastatic esophageal squamous cell carcinoma

In the present study we analyzed immunohistochemical expression of MAGE-A 3/4 and NY-ESO-1 in 55 samples of esophageal squamous cell carcinomas (ESCC) and their respective lymph node metastases. To our knowledge this is the first study to assess and compare the expression of these antigens in ESCC lymph node metastases

Multifactorial analysis of non-malignant lymphadenopathies

Cilj istraživanja: Povećani limfni čvorovi su česta pojava u ljudi. Vjerojatnost da je limfadenopatija nemaligne etiologije iznosi 80% u dobi do 40. godine života. Cilj ovog prospektivnog istraživanja (n=110 bolesnika) bile je etiološka, citomorfološka i citoimunološka karakterizacija nemalignih limfadenopatija. Ispitanici: 110 bolesnika koji su se javili na Odjel zarazne bolesti u Osijeku zbog povećanja jednog ili više limfnih čvorova. Metode: anamnestički upitnik, klinički pregled, rutinske hematološke i biokemijske pretrage, etiološka serološka dijagnostika, UZV pregled, citopunkcija, lančane reakcije polimeraze (PCR) za detekciju EBV DNK u uzorcima periferne krvi bolesnika, te imunofenotipizacija limfocita periferne krvi na protočnom citometru. Rezultati: Čak u 57% od ukupnog broja bolesnika s nemalignom limfadenopatijom serološkim testovima je dokazana EBV infekcija dok je u 21,8% bolesnika dokazana bakterijska infekcija. Toksoplazmoza je dokazana u 9,1% bolesnika, tularemija u 3,6%, miješana infekcija u 3,6%, bolest mačjeg ogreba u 2,7%, tuberkuloza u 0,9% i citomegalovirusna infekcija (CMV) u 0,9% bolesnika. U bolesnika s EBV limfadenopatijom od 6-18 godina (58%) najčešća lokalizacija povećanog limfnog čvora bila je submandibularno (45%), a potom ispred sternokleidomastoidnog mišića (41%) uz promjer 2-3 cm (72%). Najveći broj bolesnika imao je ukupan broj leukocita unutar referentnih vrijednosti (55%), no dominirala je limfocitoza (81%) s pojavom reaktivnih limfocita (57%), sedimantacija eritrocita je bila povišena (70%), a CRP unutar referentnih vrijednosti (57%). LDH je povišena (71%), kao i AST (84%) i ALT (87%), a svi citološki nalazi punktata limfnog čvora bili su reaktivna hiperplazija limfnog čvora. U 4 bolesnika s negativnom EBV serologijom dokazana je EBV DNK u perifernoj krvi. Analiza limfocitnih subpopulacija periferne krvi bolesnika s akutnom EBV infekcijom pokazala je porast subpopulacije T-limfocita, CD8+ T- limfocita i HLA-DR+ T-limfocita uz istovremeno smanjenje postotka B-limfocita i CD4+ T-limfocita u odnosu na referentne vrijednosti. Zaključak: Suvremene molekularne i imunofenotipizacijske metode imaju svoje mjesto u razjašnjavanju etiologije nemalignih limfadenopatija.Aim: Enlargement of the lymph nodes is a frequent finding. In patients younger than 40 years, about 80 % of lymphadenopathies are non-malignant. The aim of this prospective study (n = 110 patients) was a detailed characterisation of etiology, cytomorphology and cytoimmunology of non-malignant lymphadenopaties. Methods: Anamnestic data, clinical examination, routine hematological and biochemical methods, etiological serological diagnostics, ultrasound examination, cytological punction, polymerase chain reaction (PCR) for EBV DNA in the peripheral blood, flow cytometric immunophenotyping of peripheral blood lymphocytes. Results: EBV infection was the cause of lymphadenopathy in 57 % of patients. Bacterial lymphadenopathy was determined in 21% of patients, toxoplasmosis in 9,1 %, tularemia in 3,6 %, mixed infection in 3,6 %, cat scratch disease in 2,7 %, and cytomegalovirus (CMV) infection in 0,9 % of patients. In patients with EBV lymphadenopathy between ages 6–18 years (58 %), the most frequent localization of lymph nodes was a submandibulary region (45 %) as well as super ficial sternomastoid nodes (41 %). The majority of patients had normal total leukocyte numbers (55 %) with lymphocytosis (81 %) and the presence of reactive lymphocytes (57 %). Elevated levels of liver enzymes were also observed: LDH (71 % of patients), AST (84 % of patients), ALT (87 % of patients). Reactive lymph nodes hyperplasia was revealed by cytological examination of lymph nodes in all patients. EBV DNA was detectable in the peripheral blood of 4 patients without serological evidence of acute infection. Flow cytometry analysis revealed increased percentages of T-cells, CD8+T-cells, HLA-DR+T-cells as well as decreased percentages of B-cells and CD4+ T-cells in the peripheral blood of EBV-infected patients compared with healthy controls

ACHIEVED LEVEL OF TOURISM DEVELOPMENT IN THE REPUBLIC OF SERBIA

It is known that the long-standing political and economic environment in our country has stopped the development of tourism and that the quality and diverse resource base of the Republic of Serbia is not sufficiently utilized. The offer of Serbian tourism products, spontaneously developed for the needs of domestic tourism, is not able to respond to the contemporary trends of the international tourist market, because there have been major changes in the market according to which the Republic of Serbia has not adapted its tourist offer. This has directed the subject of research in this paper to determine the achieved level of tourism development in the Republic of Serbia. Based on the new demands of modern tourists and global trends in tourism, the Republic of Serbia has the opportunity to capitalize its current position, to form a tourist offer and to achieve significant growth in the tourism sector and thereby provide a place on the world tourist map

Influence of the human factor on risks in an open-pit mine

Today's turbulent business conditions are characterized by rapid technological development of the 'post-industrial' society. New technologies have caused the creation of new risks in complex techno-socio-ecological systems and up to today a lot of work is done in the aim to answer to safety demand of technology and technical equipment. After all this, human factor with its limitations and possibilities is becoming the central topic in research studies about risk and safety. This study presents study about risk of human factor, conducted in the real, high risk industrial system