A computational model for the prediction of jet entrainment in the vicinity of nozzle boattails (The BOAT code)

The basic code structure is discussed, including the overall program flow and a brief description of all subroutines. Instructions on the preparation of input data, definitions of key FORTRAN variables, sample input and output, and a complete listing of the code are presented

Environmental Effects of Space Shuttle Solid Rocket Motor Exhaust Plumes

The deposition of NOx and HCl in the stratosphere from the space shuttle solid rocket motors (SRM) and exhaust plume is discussed. A detailed comparison between stratospheric deposition rates using the baseline SRM propellant and an alternate propellant, which replaces ammonium perchlorate by ammonium nitrate, shows the total NOx deposition rate to be approximately the same for each propellant. For both propellants the ratio of the deposition rates of NOx to total chlorine-containing species is negligibly small. Rocket exhaust ground cloud transport processes in the troposphere are also examined. A brief critique of the multilayer diffusion models (presently used for predicting pollutant deposition in the troposphere) is presented, and some detailed cloud rise calculations are compared with data for Titan 3C launches. The results show that, when launch time meteorological data are used as input, the model can reasonably predict measured cloud stabilization heights

NO sub x deposited in the stratosphere by the space shuttle, phase 1

The results of calculations to determine the amount of NOx deposited in the stratosphere by space shuttle solid rocket motors (SRM) are presented. Flow properties and chemical composition in the exhaust nozzle and plume were analyzed. The nozzle calculations show that about 4.5 lbm/sec of NOx leaves the two SRMs. The total amount of NOx deposited in the stratosphere is related to the amount leaving the nozzle via an overall plume enhancement factor (OPEF), which depends upon the influence of afterburning and shocks in enhancing the exit plane NOx mole fraction. Calculations show that the OPEF is approximately 2, indicating the mass flow of NOx in the plume to be approximately l0 lbm/sec at 30 km altitude with a possible error factor of 4. For a vehicle velocity of 3750 ft/sec, therefore, the NOx deposition rate in the stratosphere is about 2.7 x 10(-3) lbm/ft

NO sub X Deposited in the Stratosphere by the Space Shuttle Solid Rocket Motors

The possible effects of the interaction of the plumes from the two solid rocket motors (SRM) from the space shuttles and mixing of the rocket exhaust products and ambient air in the base recirculation region on the total nitrous oxide deposition rate in the stratosphere were investigated. It was shown that these phenomena will not influence the total NOx deposition rate. It was also shown that uncertainties in the particle size of Al2O3, size distributions and particle/gas drag and heat transfer coefficients will not have a significant effect on the predicted NOx deposition rate. The final results show that the total mass flow of NOx leaving the plume at 30 km altitude is 4000 g./sec with a possible error factor of 3. For a vehicle velocity of 1140 meter/sec this yields an NOx deposition rate of about 3.5 g./meter. The corresponding HCl deposition rate at this altitude is about a factor of 500 greater than this value

Computational models for the viscous/inviscid analysis of jet aircraft exhaust plumes

Computational models which analyze viscous/inviscid flow processes in jet aircraft exhaust plumes are discussed. These models are component parts of an NASA-LaRC method for the prediction of nozzle afterbody drag. Inviscid/shock processes are analyzed by the SCIPAC code which is a compact version of a generalized shock capturing, inviscid plume code (SCIPPY). The SCIPAC code analyzes underexpanded jet exhaust gas mixtures with a self-contained thermodynamic package for hydrocarbon exhaust products and air. A detailed and automated treatment of the embedded subsonic zones behind Mach discs is provided in this analysis. Mixing processes along the plume interface are analyzed by two upgraded versions of an overlaid, turbulent mixing code (BOAT) developed previously for calculating nearfield jet entrainment. The BOATAC program is a frozen chemistry version of BOAT containing the aircraft thermodynamic package as SCIPAC; BOATAB is an afterburning version with a self-contained aircraft (hydrocarbon/air) finite-rate chemistry package. The coupling of viscous and inviscid flow processes is achieved by an overlaid procedure with interactive effects accounted for by a displacement thickness type correction to the inviscid plume interface

Studies supporting an upper-atmosphere chemical release program. Part I - Experimental studies on chemiluminescence. Part II - A model of releases leading to upper-atmospheric chemi-ion formation Final report, May 1965 - May 1966

Chemiluminescence of chemical compounds released in upper atmosphere and model of releases leading to upper atmospheric chemi-ionizatio

Characterization of a spark ignition system for flameholding cavities

This paper presents an experimental investigation of a capacitive-discharge spark ignition system designed to promote ignition in CH- and CH-fuelled supersonic combustors. The purpose of this study is the characterization of the ignition system and the plasma generated in the discharge. Schlieren and luminescence imaging are used to visualize the temporal evolution of the spark plasma. Transient voltages and currents across the primary-side of the ignition coil and input-side of the ignition unit are recorded using a high-speed data acquisition system. Three different ignition coils are tested with two different spark plug gaps in an attempt to increase the performance of the ignition system which is evaluated through spatially and temporally integrated luminescence recordings as well as temporally integrated photo diode signals. The data suggests that an increase in performance of a factor of 4-5 over the baseline setup can be achieved. A capacitive ignition lead is used to assess whether or not any capacitance on the coil secondary side can increase the performance of the ignition system. The experiments have also shown that the ignition system parameters can be set to cause sufficient heating of the electrodes to support ignition from a combined glow-spark plug setup

4D Imaging and Diffraction Dynamics of Single-Particle Phase Transition in Heterogeneous Ensembles

In this Letter, we introduce conical-scanning dark-field imaging in four-dimensional (4D) ultrafast electron microscopy to visualize single-particle dynamics of a polycrystalline ensemble undergoing phase transitions. Specifically, the ultrafast metal–insulator phase transition of vanadium dioxide is induced using laser excitation and followed by taking electron-pulsed, time-resolved images and diffraction patterns. The single-particle selectivity is achieved by identifying the origin of all constituent Bragg spots on Debye–Scherrer rings from the ensemble. Orientation mapping and dynamic scattering simulation of the electron diffraction patterns in the monoclinic and tetragonal phase during the transition confirm the observed behavior of Bragg spots change with time. We found that the threshold temperature for phase recovery increases with increasing particle sizes and we quantified the observation through a theoretical model developed for single-particle phase transitions. The reported methodology of conical scanning, orientation mapping in 4D imaging promises to be powerful for heterogeneous ensemble, as it enables imaging and diffraction at a given time with a full archive of structural information for each particle, for example, size, morphology, and orientation while minimizing radiation damage to the specimen

Current issues in medically assisted reproduction and genetics in Europe: research, clinical practice, ethics, legal issues and policy. European Society of Human Genetics and European Society of Human Reproduction and Embryology.

In March 2005, a group of experts from the European Society of Human Genetics and European Society of Human Reproduction and Embryology met to discuss the interface between genetics and assisted reproductive technology (ART), and published an extended background paper, recommendations and two Editorials. Seven years later, in March 2012, a follow-up interdisciplinary workshop was held, involving representatives of both professional societies, including experts from the European Union Eurogentest2 Coordination Action Project. The main goal of this meeting was to discuss developments at the interface between clinical genetics and ARTs. As more genetic causes of reproductive failure are now recognised and an increasing number of patients undergo testing of their genome before conception, either in regular health care or in the context of direct-to-consumer testing, the need for genetic counselling and preimplantation genetic diagnosis (PGD) may increase. Preimplantation genetic screening (PGS) thus far does not have evidence from randomised clinical trials to substantiate that the technique is both effective and efficient. Whole-genome sequencing may create greater challenges both in the technological and interpretational domains, and requires further reflection about the ethics of genetic testing in ART and PGD/PGS. Diagnostic laboratories should be reporting their results according to internationally accepted accreditation standards (International Standards Organisation - ISO 15189). Further studies are needed in order to address issues related to the impact of ART on epigenetic reprogramming of the early embryo. The legal landscape regarding assisted reproduction is evolving but still remains very heterogeneous and often contradictory. The lack of legal harmonisation and uneven access to infertility treatment and PGD/PGS fosters considerable cross-border reproductive care in Europe and beyond. The aim of this paper is to complement previous publications and provide an update of selected topics that have evolved since 2005

Serum screening with Down's syndrome markers to predict pre-eclampsia and small for gestational age: Systematic review and meta-analysis

<p>Abstract</p> <p>Background</p> <p>Reliable antenatal identification of pre-eclampsia and small for gestational age is crucial to judicious allocation of monitoring resources and use of preventative treatment with the prospect of improving maternal/perinatal outcome. The purpose of this systematic review was to determine the accuracy of five serum analytes used in Down's serum screening for prediction of pre-eclampsia and/or small for gestational age.</p> <p>Methods</p> <p>The data sources included Medline, Embase, Cochrane library, Medion (inception to February 2007), hand searching of relevant journals, reference list checking of included articles, contact with experts. Two reviewers independently selected the articles in which the accuracy of an analyte used in Downs's serum screening before the 25^thgestational week was associated with the occurrence of pre-eclampsia and/or small for gestational age without language restrictions. Two authors independently extracted data on study characteristics, quality and results.</p> <p>Results</p> <p>Five serum screening markers were evaluated. 44 studies, testing 169,637 pregnant women (4376 pre-eclampsia cases) and 86 studies, testing 382,005 women (20,339 fetal growth restriction cases) met the selection criteria. The results showed low predictive accuracy overall. For pre-eclampsia the best predictor was inhibin A>2.79MoM positive likelihood ratio 19.52 (8.33,45.79) and negative likelihood ratio 0.30 (0.13,0.68) (single study). For small for gestational age it was AFP>2.0MoM to predict birth weight < 10^thcentile with birth < 37 weeks positive likelihood ratio 27.96 (8.02,97.48) and negative likelihood ratio 0.78 (0.55,1.11) (single study). A potential clinical application using aspirin as a treatment is given as an example.</p> <p>There were methodological and reporting limitations in the included studies thus studies were heterogeneous giving pooled results with wide confidence intervals.</p> <p>Conclusion</p> <p>Down's serum screening analytes have low predictive accuracy for pre-eclampsia and small for gestational age. They may be a useful means of risk assessment or of use in prediction when combined with other tests.</p