Por Don Eximen Perez de Calatayu Zanoguera ... con Don Antonio de Calatayu

Sign.: []2, A-G6, H1Pag. errónea entre p. 8-11Port. con grabs. xil. representando a san Miguel Arcagel y el demonio y orlado con 2 esc. heráldico

gec estro acrop recommendations in skin brachytherapy

Abstract Purpose The aim of this publication is to compile available literature data and expert experience regarding skin brachytherapy (BT) in order to produce general recommendations on behalf of the GEC-ESTRO Group. Methods We have done an exhaustive review of published articles to look for general recommendations. Results Randomized controlled trials, systemic reviews and meta-analysis are lacking in literature and there is wide variety of prescription techniques successfully used across the radiotherapy centers. BT can be delivered as superficial application (also called contact BT or plesiotherapy) or as interstitial for tumours thicker than 5 mm within any surface, including very irregular. In selected cases, particularly in tumours located within curved surfaces, BT can be advantageous modality from dosimetric and planning point of view when compared to external beam radiotherapy. The general rule in skin BT is that the smaller the target volume, the highest dose per fraction and the shortest overall length of treatment can be used. Conclusion Skin cancer incidence is rising worldwide. BT offers an effective non-invasive or minimally invasive and relative short treatment that particularly appeals to elder and frail population

Current Progress and Future Perspectives on the Use of Bacillus clausii

Bacillus clausii is a probiotic that benefits human health. Its key characteristics include the ability to form spores; the resulting tolerance to heat, acid, and salt ensures safe passage through the human gastrointestinal tract with no loss of cells. Although B. clausii has been widely used for many decades, the beneficial properties of other probiotics, such as Lactobacillus spp. and Bifidobacterium spp., are better disseminated in the literature. In this review, we summarize the physiological, antimicrobial, and immunomodulatory properties of probiotic B. clausii strains. We also describe findings from studies that have investigated B. clausii probiotics from the perspective of quality and safety. We highlight innovative properties based on biochemical investigations of non-probiotic strains of B. clausii, revealing that B. clausii may have further health benefits in other therapeutic areas

Evaluation of a Planar Reconfigurable Phased Array Antenna Driven by a Multi-Channel Beamforming Module at Ka Band

© 2021 IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other uses, in any current or future media, including reprinting/republishing this material for advertising or promotional purposes, creating new collective works, for resale or redistribution to servers or lists, or reuse of any copyrighted component of this work in other worksIn this paper, a planar active phased array antenna demonstration with linear polarization (LP) at Ka Band (28-30 GHz) is presented. The proof of concept is carried out to evaluate the possible problems that may arise, to analyze possible calibration stages and to assess the viability of the integration of an active system with a Multi-Channel Beamforming Module (MCBM). To fulfill this task an 8times 8-element planar array arranged in column subarrays of 1times 8 elements for 1D beam steering is proposed. The single element consists of a printed circular patch connected to a microstrip feeding line through metallic vias in a multilayered structure. Both the amplitude and phase distributions are performed by a commercial integrated circuit (IC) designed for transmission purposes, from the common port to each of the 8 output ports. Thus, an evaluation of the IC performance is also included within this work. Despite the inherent amplitude and phase feeding errors of the IC, the beam-steering accuracy of the system is reasonable. A nice correspondence between the simulated and measured 8times 8-element array beam steering directions is obtained, with errors below 1° in the steering of the beamThis work was supported in part by the Spanish Government, Ministry of Economy, National Program of Research, Development and Innovation through the Project FUTURE RADIO ’’Radio systems and technologies for high capacity terrestrial and satellite communications in an hyperconnected world’’ under Grant TEC2017-85529-C3-1-R, and in part by the Project JETSTREAM ’’Desarrollo de una antena banda KA embarcada para la prestación de servicios de acceso a Internet por satélite en aviación comercial’’ in collaboration with TELNET Redes Inteligentes S.A. under Grant RTC-2015-3495-

GEC-ESTRO ACROP recommendations in skin brachytherapy

Purpose: The aim of this publication is to compile available literature data and expert experience regarding skin brachytherapy (BT) in order to produce general recommendations on behalf of the GEC-ESTRO Group. Methods: We have done an exhaustive review of published articles to look for general recommendations. Results: Randomized controlled trials, systemic reviews and meta-analysis are lacking in literature and there is wide variety of prescription techniques successfully used across the radiotherapy centers. BT can be delivered as superficial application (also called contact BT or plesiotherapy) or as interstitial for tumours thicker than 5 mm within any surface, including very irregular. In selected cases, particularly in tumours located within curved surfaces, BT can be advantageous modality from dosimetric and planning point of view when compared to external beam radiotherapy. The general rule in skin BT is that the smaller the target volume, the highest dose per fraction and the shortest overall length of treatment can be used. Conclusion: Skin cancer incidence is rising worldwide. BT offers an effective non-invasive or minimally invasive and relative short treatment that particularly appeals to elder and frail population

Plasmatic level of neurosin predicts outcome of mild cognitive impairment

<p>Abstract</p> <p>Background</p> <p>Mild Cognitive Impairment (MCI) is a disorder considered to be a transitional stage from health to dementia. Diagnosis of dementias at these early stages is always troublesome because the pathophysiologic events leading to dementia precede clinical symptoms. Thus, the development of biomarkers that can be used to support the diagnosis of dementias at early stages is rapidly becoming a high priority. We have recently reported the value of measuring plasmatic levels of neurosin in the diagnosis of Alzheimer's disease (AD). The aim of this study is to determine whether measuring plasmatic concentration of neurosin is a valuable test to predict progression of MCI.</p> <p>Methods</p> <p>Plasmatic neurosin concentrations were measured in 68 MCI patients and 70 controls subjects. Blood samples were obtained at the beginning of the study. Sixty six patients diagnosed with MCI were observed for 18 months. In 36 patients a second blood sample was obtained at the endpoint.</p> <p>Results</p> <p>The mean value of plasmatic neurosin concentration differs significantly between MCI patients who converted to Dementia with vascular component, those who converted to AD, or those who remained at MCI stage. The relative risk of developing Dementia with vascular component when neurosin levels are higher than 5.25 ng/ml is 13 while the relative risk of developing mild AD when neurosin levels are lower than 5.25 ng/ml is 2. Increases in the levels of neurosin indicate progression to Dementia with vascular component.</p> <p>Conclusion</p> <p>The measurement of plasmatic neurosin level in patients diagnosed with MCI may predict conversion from MCI to Dementia with vascular component. A single measurement is also valuable to estimate the risk of developing AD and Dementia with vascular component. Finally, repeated measurement of plasmatic neurosin might be a useful test to predict outcome in patients with MCI.</p