4,883 research outputs found
Tips for Planning a Successful Timber Sale
This fact sheet describes 12 steps to follow to help ensure a successful timber sale. Important points to consider when preparing a timber harvest are included, but this publication is intended only as an introduction to the subject. Other fact sheets in this series will address related topics, such as forest management planning and timber sale contract provisions, in more detail
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Flavor Anarchy in a Randall-Sundrum Model with 5D Minimal Flavor Violation and a Low Kaluza-Klein Scale
A variant of a warped extra dimension model is presented. It is based on 5D minimal flavor violation, in which the only sources of flavor breaking are two 5D anarchic Yukawa matrices. These matrices also control the bulk masses, which are responsible for the resulting flavor hierarchy. The theory flows to a next to minimal flavor violation model where flavor violation is dominantly coming from the 3rd generation. Flavor violation is also suppressed by a parameter that dials the violation in the up or down sector. There is therefore a sharp limit in which there is no flavor violation in the down-type quark sector which, remarkably, is consistent with the observed flavor parameters. This is used to eliminate the current Randall-Sundrum flavor and CP problem. Our construction suggests that strong dynamic-based, flavor models may be built based on the same concepts.Physic
Forest Management Planning
Forest management planning is a process that helps you identify the resources and opportunities available on your property and what you would like to realize from your property in terms of financial gain and long-term enjoyment. What do you want from your forest land? What do you want your forest to look like in the future? What about your forest is most important to you? Forest management planning is a means to identify what can be done to enhance and protect the values and aspects of your property that are most important to you. These aspects might include wildlife, recreation, aesthetics, timber, livestock ranching, inheritance values, and others
Finding the Epicenter of I-O Psychology
Where is the epicenter of I-O psychology in the U.S.? Where is the location around which all research, teaching and consulting revolves? Is it East Lansing, the home of Michigan State? No. Is it Bowling Green, Ohio, SIOP headquarters? No, but you are getting closer. How about Champaign, IL? Is the University of Illinois the epicenter? Warmer still, but not quite there. The center of U.S. I-O psychology is Mount Vernon, Illinois
The gifted and talented : children with unlimited horizons
Includes bibliographical references.Educating gifted and talented students has become a difficult task for teachers. This capstone examines the various methods used to identify gifted students and their needs. Programs and schools that offer assistance in educating gifted students are introduced and explained in detail. The Gifted and Talented: Children with Unlimited Horizons presents the method of using a literature curriculum that highlights children's tradebooks as a way to enhance the learning experience for gifted students. Included in the capstone is a booklist of children's tradebooks, summaries and extensions of these books for a model 4th grade social studies curriculum. To gather information a variety of sources were consulted. I solicited copies of various magazines and journals that specialized in educating the gifted and providing support services for them. I researched the topic in literature sources that concentrated on the study of gifted education. I also searched the Internet for schools that provided gifted education across the country. I found that many gifted students are lost in the shuffle of regular education. Too frequently, the gifted are not challenged and never reach their full potential. By using tradebooks to enrich and supplement the curriculum, teachers can tap into the learning potential of these children.B.S.Ed. (Bachelor of Science in Education
Reactive and inhibiting species in the electrocatalytic oxidation of glycerol on gold : A study combining in-situ visible reflectance and ATR-SEIRAS
Acknowledgements: The support of the Leverhulme Trust through the Doctoral Scholarship Scheme [DS-2017-073] is gratefully acknowledged.Peer reviewedPostprin
Co-Incubation with PPARĪ²/Ī“ Agonists and Antagonists Modeled Using Computational Chemistry: Effect on LPS Induced Inflammatory Markers in Pulmonary Artery
Ā© 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/)Peroxisome proliferator activated receptor beta/delta (PPARĪ²/Ī“) is a nuclear receptor ubiquitously expressed in cells, whose signaling controls inflammation. There are large discrepan-cies in understanding the complex role of PPARĪ²/Ī“ in disease, having both antiā and proāeffects on inflammation. After ligand activation, PPARĪ²/Ī“ regulates genes by two different mechanisms; induction and transrepression, the effects of which are difficult to differentiate directly. We studied the PPARĪ²/Ī“āregulation of lipopolysaccharide (LPS) induced inflammation (indicated by release of nitrite and ILā6) of rat pulmonary artery, using different combinations of agonists (GW0742 or Lā165402) and antagonists (GSK3787 or GSK0660). LPS induced release of NO and ILā6 is not significantly reduced by incubation with PPARĪ²/Ī“ ligands (either agonist or antagonist), however, co-incubation with an agonist and antagonist significantly reduces LPSāinduced nitrite production and Nos2 mRNA expression. In contrast, incubation with LPS and PPARĪ²/Ī“ agonists leads to a significant increase in Pdkā4 and Angptlā4 mRNA expression, which is significantly decreased in the presence of PPARĪ²/Ī“ antagonists. Docking using computational chemistry methods indicates that PPARĪ²/Ī“ agonists form polar bonds with His287, His413 and Tyr437, while antagonists are more promiscuous about which amino acids they bind to, although they are very prone to bind Thr252 and Asn307. Dual binding in the PPARĪ²/Ī“ binding pocket indicates the ligands retain similar binding energies, which suggests that coāincubation with both agonist and antagonist does not prevent the specific binding of each other to the large PPARĪ²/Ī“ binding pocket. To our knowledge, this is the first time that the possibility of binding two ligands simultaneously into the PPARĪ²/Ī“ binding pocket has been explored. Agonist binding followed by antagonist simultaneously switches the PPARĪ²/Ī“ mode of action from induction to transrepression, which is linked with an increase in Nos2 mRNA expression and nitrite production.Peer reviewedFinal Published versio
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