A Note on Real Tunneling Geometries

In the Hartle-Hawking ``no boundary'' approach to quantum cosmology, a real tunneling geometry is a configuration that represents a transition from a compact Riemannian spacetime to a Lorentzian universe. I complete an earlier proof that in three spacetime dimensions, such a transition is ``probable,'' in the sense that the required Riemannian geometry yields a genuine maximum of the semiclassical wave function.Comment: 5 page

The Simplicial Ricci Tensor

The Ricci tensor (Ric) is fundamental to Einstein's geometric theory of gravitation. The 3-dimensional Ric of a spacelike surface vanishes at the moment of time symmetry for vacuum spacetimes. The 4-dimensional Ric is the Einstein tensor for such spacetimes. More recently the Ric was used by Hamilton to define a non-linear, diffusive Ricci flow (RF) that was fundamental to Perelman's proof of the Poincare conjecture. Analytic applications of RF can be found in many fields including general relativity and mathematics. Numerically it has been applied broadly to communication networks, medical physics, computer design and more. In this paper, we use Regge calculus (RC) to provide the first geometric discretization of the Ric. This result is fundamental for higher-dimensional generalizations of discrete RF. We construct this tensor on both the simplicial lattice and its dual and prove their equivalence. We show that the Ric is an edge-based weighted average of deficit divided by an edge-based weighted average of dual area -- an expression similar to the vertex-based weighted average of the scalar curvature reported recently. We use this Ric in a third and independent geometric derivation of the RC Einstein tensor in arbitrary dimension.Comment: 19 pages, 2 figure

Ricci flows, wormholes and critical phenomena

We study the evolution of wormhole geometries under Ricci flow using numerical methods. Depending on values of initial data parameters, wormhole throats either pinch off or evolve to a monotonically growing state. The transition between these two behaviors exhibits a from of critical phenomena reminiscent of that observed in gravitational collapse. Similar results are obtained for initial data that describe space bubbles attached to asymptotically flat regions. Our numerical methods are applicable to "matter-coupled" Ricci flows derived from conformal invariance in string theory.Comment: 8 pages, 5 figures. References added and minor changes to match version accepted by CQG as a fast track communicatio

the case of tobacco control

publishersversionpublishe

The layered crisis of the primary care medical workforce in the European region: what evidence do we need to identify causes and solutions?

Publisher Copyright: © 2023, The Author(s).Primary care services are key to population health and for the efficient and equitable organisation of national health systems. This is why they are often financed through public funds. Primary care doctors are instrumental for the delivery of preventive services, continuity of care, and for the referral of patients through the system. These cadres are also the single largest health expenditure at the core of such services. Although recruitment and retention of primary care doctors have always been challenging, shortages are now exacerbated by higher demand for services from aging populations, increased burden of chronic diseases, backlogs from the COVID-19 pandemic, and patient expectations. At the same time, the supply of primary care physicians is constrained by rising retirement rates, internal and external migration, worsening working conditions, budget cuts, and increased burnout. Misalignment between national education sectors and labour markets is becoming apparent, compounding staff shortages and maldistribution. With their predominantly publicly funded health systems and in the aftermath of COVID-19, countries of the European region appear to be now on the cusp of a multi-layered, slow-burning primary care crisis, with almost every country reporting long waiting lists for doctor appointments, shortages of physicians, unfilled vacancies, and consequently, added pressures on hospitals’ Accident and Emergency services. This articles collection aims at pulling together the evidence from countries of the European Region on root causes of such workforce crisis, impacts, and effectiveness of existing policies to mitigate it. Original research is needed, offering analysis and fresh insights into the primary care medical workforce crisis in wider Europe. Ultimately, the aim of this articles collection is to provide an evidence basis for the identification of policy solutions to present and future primary health care crises in high as well as lower-income countries.publishersversionpublishe

Investigating Off-shell Stability of Anti-de Sitter Space in String Theory

We propose an investigation of stability of vacua in string theory by studying their stability with respect to a (suitable) world-sheet renormalization group (RG) flow. We prove geometric stability of (Euclidean) anti-de Sitter (AdS) space (i.e., $\mathbf{H}^n$) with respect to the simplest RG flow in closed string theory, the Ricci flow. AdS space is not a fixed point of Ricci flow. We therefore choose an appropriate flow for which it is a fixed point, prove a linear stability result for AdS space with respect to this flow, and then show this implies its geometric stability with respect to Ricci flow. The techniques used can be generalized to RG flows involving other fields. We also discuss tools from the mathematics of geometric flows that can be used to study stability of string vacua.Comment: 29 pages, references added in this version to appear in Classical and Quantum Gravit

Construction of two whole genome radiation hybrid panels for dromedary (Camelus dromedarius): 5000RAD and 15000RAD

The availability of genomic resources including linkage information for camelids has been very limited. Here, we describe the construction of a set of two radiation hybrid (RH) panels (5000RAD and 15000RAD) for the dromedary (Camelus dromedarius) as a permanent genetic resource for camel genome researchers worldwide. For the 5000RAD panel, a total of 245 female camel-hamster radiation hybrid clones were collected, of which 186 were screened with 44 custom designed marker loci distributed throughout camel genome. The overall mean retention frequency (RF) of the final set of 93 hybrids was 47.7%. For the 15000RAD panel, 238 male dromedary-hamster radiation hybrid clones were collected, of which 93 were tested using 44 PCR markers. The final set of 90 clones had a mean RF of 39.9%. This 15000RAD panel is an important high-resolution complement to the main 5000RAD panel and an indispensable tool for resolving complex genomic regions. This valuable genetic resource of dromedary RH panels is expected to be instrumental for constructing a high resolution camel genome map. Construction of the set of RH panels is essential step toward chromosome level reference quality genome assembly that is critical for advancing camelid genomics and the development of custom genomic tools

Multi-level automated sub-zoning of water distribution systems

Water distribution systems (WDS) are complex pipe networks with looped and branching topologies that often comprise of thousands of links and nodes. This work presents a generic framework for improved analysis and management of WDS by partitioning the system into smaller (almost) independent sub-systems with balanced loads and minimal number of interconnections. This paper compares the performance of three classes of unsupervised learning algorithms from graph theory for practical sub-zoning of WDS: (1) Graph clustering – a bottom-up algorithm for clustering n objects with respect to a similarity function, (2) Community structure – a bottom-up algorithm based on network modularity property, which is a measure of the quality of network partition to clusters versus randomly generated graph with respect to the same nodal degree, and (3) Graph partitioning – a flat partitioning algorithm for dividing a network with n nodes into k clusters, such that the total weight of edges crossing between clusters is minimized and the loads of all the clusters are balanced. The algorithms are adapted to WDS to provide a decision support tool for water utilities. The proposed methods are applied and results are demonstrated for a large-scale water distribution system serving heavily populated areas in Singapore

Ricci flow and black holes

Gradient flow in a potential energy (or Euclidean action) landscape provides a natural set of paths connecting different saddle points. We apply this method to General Relativity, where gradient flow is Ricci flow, and focus on the example of 4-dimensional Euclidean gravity with boundary S^1 x S^2, representing the canonical ensemble for gravity in a box. At high temperature the action has three saddle points: hot flat space and a large and small black hole. Adding a time direction, these also give static 5-dimensional Kaluza-Klein solutions, whose potential energy equals the 4-dimensional action. The small black hole has a Gross-Perry-Yaffe-type negative mode, and is therefore unstable under Ricci flow. We numerically simulate the two flows seeded by this mode, finding that they lead to the large black hole and to hot flat space respectively, in the latter case via a topology-changing singularity. In the context of string theory these flows are world-sheet renormalization group trajectories. We also use them to construct a novel free energy diagram for the canonical ensemble.Comment: 31 pages, 14 color figures. v2: Discussion of the metric on the space of metrics corrected and expanded, references adde

Topological mirror symmetry with fluxes

Motivated by SU(3) structure compactifications, we show explicitly how to construct half--flat topological mirrors to Calabi--Yau manifolds with NS fluxes. Units of flux are exchanged with torsion factors in the cohomology of the mirror; this is the topological complement of previous differential--geometric mirror rules. The construction modifies explicit SYZ fibrations for compact Calabi--Yaus. The results are of independent interest for SU(3) compactifications. For example one can exhibit explicitly which massive forms should be used for Kaluza--Klein reduction, proving previous conjectures. Formality shows that these forms carry no topological information; this is also confirmed by infrared limits and old classification theorems.Comment: 35 pages, 5 figure