3,383 research outputs found

    Developing Critical Language Awareness via Service-Learning for Spanish Heritage Speakers

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    In recent years a growing number of researchers have urged for the adoption of critical pedagogies for the teaching of Spanish as a heritage language (SHL) in the US (Leeman, 2012; Leeman, Rabin & Roman-Mendoza, 2011). Such critical stances to SHL instruction acknowledge the dynamic interplay between language, power, identity and ideology and aim to develop critical language awareness among students in which students gain an understanding of social hierarchies and language subordination. Merging this critical perspective with approaches that unite SHL learners and communities through service-learning programs (Martinez, 2010; Villa, 2010), the current paper examines how service-learning can accomplish critical pedagogical goals. Bridging the fields of sociolinguistics and language pedagogy, the current study examines data collected over four semesters from student journals, interviews and questionnaires in a university Spanish heritage speakers course with service-learning. Qualitative and quantitative analyses explore students’ perspectives on language use, sociolinguistic variation, identity and connectedness to the Latino community. This study demonstrates how service-learning contributes to the development of students’ awareness of sociolinguistic and sociopolitical issues affecting local Latino communities and the construction of positive identities. Expanding on sociolinguistic research aimed to better meet the needs of SHL learners (see Carreira, 2003; Potowski, 2005; Martinez, 2003; Valdes, 2001), the current study makes critical pedagogical considerations for SHL instruction, with particular emphasis on how to integrate discussions of sociolinguistic variation and language ideologies into the SHL classroom and how to raise critical language awareness among SHL students through community engagement. Overall, this study addresses the complex relationship between language, power, ideology and identity in SHL instruction

    Tortoiseshell or polymer? Spectroscopic analysis to redefine a purported tortoiseshell box with gold decorations as a plastic box with brass

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    The study and preservation of museum collections requires complete knowledge and understanding of constituent materials that can be natural, synthetic, or semi-synthetic polymers. In former times, objects were incorporated in museum collections and classified solely by their appearance. New studies, prompted by severe degradation processes or conservation-restoration actions, help shed light on the materiality of objects that can contradict the original information or assumptions. The selected case study presented here is of a box dating from the beginning of the 20th century that belongs to the Portuguese National Ancient Art Museum. Museum curators classified it as a tortoiseshell box decorated with gold applications solely on the basis of visual inspection and the information provided by the donor. This box has visible signs of degradation with white veils, initially assumed to be the result of biological degradation of a proteinaceous matrix. This paper presents the methodological rationale behind this study and proposes a totally non-invasive methodology for the identification of polymeric materials in museum artifacts. The analysis of surface leachates using H-1 and C-13 nuclear magnetic resonance (NMR) complemented by in situ attenuated total reflection infrared spectroscopy (ATR FT-IR) allowed for full characterization of the object s substratum. The NMR technique unequivocally identified a great number of additives and ATR FT-IR provided information about the polymer structure and while also confirming the presence of additives. The pressure applied during ATR FT-IR spectroscopy did not cause any physical change in the structure of the material at the level of the surface (e.g., color, texture, brightness, etc.). In this study, variable pressure scanning electron microscopy (VP-SEM-EDS) was also used to obtain the elemental composition of the metallic decorations. Additionally, microbiologic and enzymatic assays were performed in order to identify the possible biofilm composition and understand the role of microorganisms in the biodeterioration process. Using these methodologies, the box was correctly identified as being made of cellulose acetate plastic with brass decorations and the white film was identified as being composed mainly of polymer exudates, namely sulphonamides and triphenyl phosphate

    Brain Abscess: a Rare Clinical Case with Oral Etiology

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    Brain abscess is a very rare condition but has a significant mortality rate. The three main routes of inoculation are trauma, contiguous focus, and the hematogenous route. The odontogenic focus is infrequent and is usually a diagnosis of exclusion. This paper presents a brain abscess case proven to be of dental origin, caused by Actinomyces meyeri and Fusobacterium nucleatum. This case highlights the risk underlying untreated dental disease and why oral infectious foci removal and good oral health are essential in primary care.info:eu-repo/semantics/publishedVersio

    Dapagliflozin Impact on the Exercise Capacity of Non-Diabetic Heart Failure with Reduced Ejection Fraction Patients

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    Background: Dapagliflozin has been shown to reduce morbidity and mortality in Heart Failure with reduced Ejection Fraction (HFrEF), but its impact on exercise capacity of non-diabetic HF outpatients is unknown. Methods: Adult non-diabetic HF patients with a left ventricular ejection fraction (LVEF) <50% were randomized 1:1 to receive dapagliflozin 10 mg or to continue with HF medication. Patients underwent an initial evaluation which was repeated after 6 months. The variation of several clinical parameters was compared, with the primary endpoint being the 6 month peak oxygen uptake (pVO2) variation. Results: A total of 40 patients were included (mean age 61 ± 13 years, 82.5% male, mean LVEF 34 ± 5%), half being randomized to dapagliflozin, with no significant baseline differences between groups. The reported drug compliance was 100%, with no major safety events. No statistically significant difference in HF events was found (p = 0.609). There was a 24% reduction in the number of patients in New York Heart Association (NYHA) class III in the treatment group as opposed to a 15.8% increase in the control group (p = 0.004). Patients under dapagliflozin had a greater improvement in pVO2 (3.1 vs. 0.1 mL/kg/min, p = 0.030) and a greater reduction in NT-proBNP levels (-217.6 vs. 650.3 pg/mL, p = 0.007). Conclusion: Dapagliflozin was associated with a significant improvement in cardiopulmonary fitness at 6 months follow-up in non-diabetic HFrEF patients.info:eu-repo/semantics/publishedVersio

    O Valor Prognóstico do Ponto Ótimo Cardiorrespiratório após Prova de Esforço Cardiorrespiratória Submáxima na Insuficiência Cardíaca

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    Introduction: Peak oxygen consumption (pVO2) is a key parameter for assessing the prognosis of heart failure with reduced ejection fraction (HFrEF). However, it is less reliable when the cardiopulmonary exercise test (CPET) is not maximal. Objective: To compare the prognostic power of various exercise parameters in submaximal CPET. Methods: Adult patients with HFrEF undergoing CPET in a tertiary center were prospectively assessed. Submaximal CPET was defined as a respiratory exchange ratio ≤1.10. Patients were followed for one year for the primary endpoint of cardiac death and urgent heart transplantation (HT). Various CPET parameters were analyzed as potential predictors of the combined endpoint and their prognostic power (area under the curve [AUC]) was compared using the Hanley-McNeil test. Results: CPET was performed in 442 HFrEF patients (mean age 56±12 years, 80% male), of whom 290 (66%) had a submaximal CPET. Seventeen patients (6%) reached the primary endpoint. The cardiorespiratory optimal point (COP) had the highest AUC value (0.989, p<0.001), and significantly higher prognostic power than other tested parameters, with pVO2 presenting an AUC of 0.753 (p=0.001). COP ≥36 had significantly lower survival free of HT during follow-up (p<0.001) and presented a sensitivity of 100% and a specificity of 89% for the primary endpoint. Conclusion: COP had the highest prognostic power of all parameters analyzed in a submaximal CPET. This parameter can help stratify HFrEF patients who are physiologically unable to reach a maximal level of exercise.info:eu-repo/semantics/publishedVersio

    Hyaluronidase recruits mesenchymal-like cells to the lung and ameliorates fibrosis

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    Hyaluronidases (HYALs) comprise a group of enzymes that degrade hyaluronic acid (HA). In this report, we reveal that a single intranasal inoculation of HYAL induces an increase in mononuclear cells within the bronchoalveolar space demonstrating a mesenchymal-like phenotype, expressing stem cell antigen-1 (SCA-1), CD44 and CD73 but not CD34, CD45, CD3, CD4, CD8 or CD19. This influx of mesenchymal stem cell (MSC)-like cells was dependent on leukotriene production within the lung parenchyma. These findings prompted experiments demonstrating that HYAL treatment potently blocked bleomycin-induced lung injury and fibrosis while decreasing transforming growth factor (TGF)-β production and collagen deposition. These data suggest that HYAL is a novel and promising tool to use autologous MSC-like cells in the treatment of pulmonary fibrosis

    Why should we screen for perinatal depression? Ten reasons to do it

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    In this paper we review some of the best available evidence to argue that screening for perinatal depression should be systematically conducted since pregnancy. Our view is organized in ten topics: (1) perinatal depression high prevalence; (2) its potential negative consequences, including maternal, conjugal, foetal, infantile, and child effects; (3) its under-detection and treatment; (4) its stigma; (5) the professionals and women misconceptions related to perinatal depression; (6) the availability of valid and short self-report screening instruments for perinatal depression and (7) their acceptability; (8) the increase in recognition, diagnosis, and treatment rates in comparison with routine practice; (9) the opportunity, given the large number of contacts that women have with health professionals in the perinatal period; and (10) perinatal depression screening potential cost-effectiveness

    Perfeccionismo no transtorno obsessivo-compulsivo e nos transtornos alimentares

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    OBJETIVO: Este estudo tem dois objetivos principais. Primeiro, avaliar as dimensões do perfeccionismo no transtorno obsessivo-compulsivo e nos transtornos alimentares em comparação com duas amostras controle: psiquiátrica (depressão/ansiedade) e não clínica. Segundo, avaliar se o perfeccionismo é um traço de personalidade especificamente relacionado com estas diferentes condições clínicas. MÉTODO: 39 pacientes com transtorno obsessivo-compulsivo, 24 com transtornos alimentares, 65 com um diagnóstico de depressão e/ou ansiedade (todos estes pacientes encontravam-se em regime de ambulatório) e 70 controles não clínicos completaram a versão portuguesa da Multidimensional Perfectionism Scale. RESULTADOS: Comparativamente à amostra não clínica, todas as amostras clínicas apresentaram níveis significativamente mais elevados na Multidimensional Perfectionism Scale total, no Perfeccionismo Auto-Orientado e no Perfeccionismo-Socialmente-Prescrito. Não houve diferenças estatisticamente significativas no Perfeccionismo-Auto-Orientado e na Multidimensional Perfectionism Scale total nas três amostras clínicas. No entanto, a amostra com transtornos alimentares apresentou níveis significativamente mais elevados de Perfeccionismo-Socialmente-Prescrito, comparativamente à transtornos alimentares e à amostra psiquiátrica (depressão/ansiedade). CONCLUSÃO: O perfeccionismo revelou estar associado a uma grande variedade de condições psicopatológicas. Contudo, as diferenças encontradas entre a amostra de transtornos alimentares, de transtorno obsessivo-compulsivo e a psiquiátrica no Perfeccionismo-Socialmente-Prescrito necessitam de investigação subsequente no sentido de clarificar a especificidade desta dimensão com os transtornos alimentares

    Displasia Cimento Óssea Florida: Apresentação Rara de um Problema Comum

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    Introdução A displasia cimento-óssea (DCO) é a lesão fibro-óssea mais comum. Pensa-se que a DCO tem origem no ligamento periodontal. Outros acreditam que tem origem num defeito da remodelação óssea desencadeada por lesões locais. Com base nas características clínicas e radiográficas, as DCO dividem-se em focal, periapical e florida. A DCO florida caracteriza-se por um envolvimento multifocal não limitado aos segmentos anteriores. Esta forma afecta sobretudo mulheres melanodérmicas com particular incidência nos adultos de meia-idade e idosos. Caracteriza-se por lesões bilaterais e por vezes simétricas. Normalmente estas lesões são assintomáticas podendo tratar-se de achados radiográficos. Noutros casos pode haver dor ligeira, fístulas alveolares e exposição óssea. Raramente pode haver expansão óssea. Radiograficamente, apresentam um padrão semelhante às outras formas de DCO. Inicialmente as lesões são radiotransparentes, adquirindo um padrão misto e posteriormente tornam-se radiopacas com halo radiotransparente. Caso Clínico Mulher, 53 anos, originária da Índia, com Diabetes Mellitus tipo 2. Vai a consulta de Cirurgia de Cabeça e Pescoço no IPO Lisboa enviada pelo médico de família com a informação de ser seguida em Oncologia na Índia por “neoplasia óssea com atingimento a nível de mandíbula e maxilar superior com destruição óssea progressiva”. Clinicamente refere desde há 20 anos parestesias na hemimandíbula esquerda com instalação de dor há 10 anos. Com recente irradiação da dor para a nuca. À observação tem gengivite tartárica, sem outras alterações. Traz consigo duas TC-Cone Beam (2012 e 2017) que mostram a existência e evolução de cinco lesões junto às regiões de 13-14, 23-25, 33, 36 e 46. As múltiplas lesões eram sugestivas do diagnóstico de DCO florida. Pediu-se TC Maxilofacial e manteve-se a sob vigilância medicando-se sintomaticamente. Discussão e Conclusões Nas DCO periapical e florida, os achados clínicos e radiográficos permitem fazer um diagnóstico presuntivo. As características da DCO focal são menos específicas e por isso a biopsia pode ser necessária. A DCO não tem natureza neoplásica e geralmente não requer remoção sendo que para um paciente assintomático a reavaliação periódica e o controlo da doença periodontal estão indicados. Raramente, estas lesões apresentam um crescimento progressivo (displasia óssea expansiva) com necessidade de remoção. Em geral, o prognóstico é bom. O desenvolvimento de sarcomas em áreas de DCO está relatado mas é muito raro.info:eu-repo/semantics/publishedVersio

    Infeção da Cavidade Oral Associada a Ventilação Não Invasiva

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