3,198 research outputs found
The integration of indigenous knowledge in school: a systematic review
Indigenous knowledge is generally recognised as an inferior social experience in spaces of knowledge production. The educational issue that results from this process imposes barriers to the integration of these epistemologies in the school environment. This study presents a systematic review about the integration of indigenous knowledge in primary schools in developing and/or emerging countries and the results of these interventions. Through a search carried out in the electronic database b-on, from the Faculty of Psychology and Education Sciences of the University of Porto in Portugal, 14 studies were selected. This review identified factors that influence the representation of the indigenous culture in the school environment, allowing the construction of a framework in which indigenous knowledge is often neglected in the formal education system with obstacles to its introduction into the school environment. It also revealed that the understanding of the local context is essential in proposing interventions to open a possible intercultural dialogue. (c) 2023 British Association for International and Comparative Education
Underwater Acoustic Source Localization and Sounds Classification in Distributed Measurement Networks
info:eu-repo/semantics/publishedVersio
Water Quality Monitoring and Associated Distributed Measurement Systems: An Overview
info:eu-repo/semantics/publishedVersio
Relatório de Estågio Programas de Treino de Força e Multicomponente para Idosos
O presente RelatĂłrio de EstĂĄgio estĂĄ integrado no 2Âș Ciclo em Atividade
FĂsica para a Terceira Idade da Faculdade de Desporto da Universidade do Porto
e tem por objetivo a descrição e a reflexão do trabalho pråtico realizado no ano
letivo de 2019-2020.
Para a elaboração deste documento, foram contempladas as atividades
de planeamento, aplicação e reflexão do processo de treino a seis grupos de
idosos: i) um grupo de Treino de Força para idosos autónomos e independentes,
ii) trĂȘs grupos de Treino Multicomponente para idosos autĂłnomos e
independentes e iii) dois grupos de Treino Multicomponente para idosos com
DemĂȘncia. As sessĂ”es de treino decorreram nas instalaçÔes da Faculdade de
Desporto da Universidade do Porto e nas instalaçÔes "Os FĂsicos", na Senhora
da Hora.
Os programas de treino procuraram estar em conformidade com as
recomendaçÔes do exercĂcio fĂsico para a população idosa. Todos os idosos
foram avaliados no inĂcio e no final do ano de treino (Outubro e Junho)
relativamente Ă aptidĂŁo fĂsica de acordo com o protocolo Senior Fitness Test.
Dados os acontecimentos durante o ano de 2020, nomeadamente a pandemia
mundial de COVID-19, os programas foram interrompidos de Março a Junho,
perĂodo durante o qual realizamos sessĂ”es treino online. Os efeitos dos
programas de treino foram observados atravĂ©s da estatĂstica descritiva (mĂ©dia e
desvio padrão) e de um teste de hipóteses não paramétrico (Wilcoxon).This internship report was integrated in the 2nd year of the 2nd Cycle in
Physical Activity for Elderly at the Faculty of Sports of University of Porto. This
report aims to describe and reflect on the practical work done in the 2019-2020
school year.
This document includes the planning, application and reflection of the
activities involved in the training process of six groups of older adults: i) a strength
training group for autonomous and independentolder adults, ii) three
multicomponent training group for autonomous and independent older adults;
and iii) two groups of multicomponent training for the older adults with dementia.
The training sessions took place at the Faculty of Sports of the University of Porto
and at "Os FĂsicos" in Senhora da Hora.
The training programs were based on the recommendations of physical
exercise for the elderly. All seniors were assessed at the beginning and end of
the training year (October and June) for physical fitness according to the Senior
Fitness Test protocol. The effects of training programs were observed through
descriptive statistics (mean and standard deviation) and non-parametric
hipothesis test (Wilcoxon)
Caracterização do potencial patogénico de duas estirpes distintas de "Pseudomonas aeruginosa"
Dissertação de mestrado em BioquĂmica Aplicada (ĂĄrea de especialização em Biomedicina)Pseudomonas aeruginosa is an opportunist and ubiquitous pathogen, displaying high levels of antibiotic resistance and proliferating in many environments, including healthcare facilities. The high infectivity of this pathogen in impaired and immunocompromised patients, especially cystic fibrosis patients, leads to high rates of morbidity and mortality. It is no surprise that this bacterium became one of the main concerns regarding nosocomial infections, and so forth driven the attention of many researchers to study and characterize this pathogen.
A collaboration between the Molecular and Environment Biology Centre of the University of Minho and the Hospital of Braga, provided two different clinical isolates from the sputum of the patients infected with Pseudomonas aeruginosa, classified as HB13 and HB15. The strain HB13 does not produce pigments and evidenced resistance to a wide range of antibiotics. On the other hand, the strain HB15 produces a significant quantity of pyocianin pigments and is susceptible to antibiotics. The Pseudomonas aeruginosa strain PAO1 was used in this thesis work as a reference strain. These strains were selected to assess their levels of cytotoxicity, in the L929 and A549 cell lines by incubation with the strainsâ secreted virulence factors. Morphological changes and oxidative stress induced in these cell lines were also considered in this thesis work.
The cytotoxicity study outcomes showed that the Pseudomonas aeruginosa strains when growing out of an infection context, were still able to produce a set of secreted virulence factors that induced high levels of cellular death on L929 and A549 cells. Previous literature established that the HB15 strain is more pathogenic than the HB13 strain, demonstrating a pathogenic pattern close to the PAO1 strain. The analysis of the morphology of the L929 and A549 cells, incubated with the strainsâ virulence factors, by contrast phase microscopy and fluorescence microscopy, unveiled several cellular morphology alterations, such as cell agglutination, loss of cellular shape, cellular blebbing, evidences of apoptotic bodies, cytoskeleton disorganization and nuclear fragmentation. The results of the oxidative stress study showed that in the early stages of incubation with the strainsâ virulence factors, the cell lines increased the production of reactive oxygen species, leading to an intensification of oxidative stress, pointed out as one of the causes of the Pseudomonas aeruginosa strains cytotoxicity.
This thesis work paved the way for perceiving and understanding the pathogenic potential of these strains, and future work should be directed in order to achieve a more complete assessment of the mechanisms and cellular processes underlying the pathogenicity of these strains.A Pseudomonas aeruginosa Ă© um patogĂ©neo oportunista e ubĂquo, exibindo altos nĂveis de resistĂȘncia a antibiĂłticos e proliferando em muitos ambientes, incluindo unidades de saĂșde. A alta infecciosidade deste patogĂ©neo em pacientes debilitados e imunocomprometidos, especialmente em pacientes com fibrose cĂstica, estĂĄ associada a altas taxas de morbidade e mortalidade. NĂŁo Ă© de estranhar que esta bactĂ©ria se tenha tornado numa das principais preocupaçÔes em termos de infeçÔes hospitalares, e por conseguinte, motivado vĂĄrios trabalhos de caracterização deste patogĂ©neo.
Uma colaboração entre o Centro de Biologia Molecular e Ambiental da Universidade do Minho e o Hospital de Braga permitiu o acesso a dois diferentes isolados clĂnicos do muco pulmonar dos pacientes infetados com Pseudomonas aeruginosa, designados como HB13 e HB15. A estirpe HB13 nĂŁo produz pigmentos e evidenciou resistĂȘncia a uma ampla gama de antibiĂłticos. Por outro lado, a estirpe HB15 produz uma quantidade significativa de piocianina e Ă© suscetĂvel a antibiĂłticos. A estirpe PAO1 da Pseudomonas aeruginosa foi utilizada neste trabalho de tese como estirpe de referĂȘncia. Estas estirpes foram selecionadas para avaliar os seus nĂveis de citotoxicidade nas linhas celulares L929 e A549, por incubação com os fatores de virulĂȘncia segregados. As alteraçÔes morfolĂłgicas e stress oxidativo induzido nestas linhas celulares foram tambĂ©m consideradas neste trabalho de tese.
Os resultados do estudo de citotoxicidade mostraram que as estirpes de Pseudomonas aeruginosa quando proliferando fora de um contexto de infeção, continuam capazes de produzir um conjunto de fatores de virulĂȘncia segregados que induziram altos nĂveis de inviabilidade celular nas cĂ©lulas L929 e A549. De acordo com a literatura, estabeleceu-se que a estirpe HB15 Ă© mais patogĂȘnica do que a estirpe HB13, demonstrando um padrĂŁo de patogenicidade semelhante ao da estirpe PAO1. A anĂĄlise da morfologia das cĂ©lulas L929 e A549, incubadas com os fatores de virulĂȘncia das estirpes, por microscopia de contraste de fase e microscopia de fluorescĂȘncia, revelou vĂĄrias alteraçÔes na morfologia celular, tais como aglutinação celular, alteração da morfologia celular, formação de corpos apoptĂłticos, desorganização do citoesqueleto e fragmentação nuclear. Os resultados do estudo de stress oxidativo mostraram que, nas fases iniciais de incubação com os fatores de virulĂȘncia das estirpes, as linhas celulares aumentaram a produção de espĂ©cies reativas de oxigĂ©nio, conduzindo a uma intensificação do stress oxidativo, apontado como uma das causas da citotoxicidade das estirpes testadas da Pseudomonas aeruginosa.
Este trabalho de tese abriu caminho para uma melhor compreensĂŁo do potencial patogĂȘnico destas estirpes e trabalhos futuros devem ser direcionados a fim de conseguir-se uma avaliação mais completa dos mecanismos e processos celulares subjacentes Ă patogenicidade destas estirpes
Monoclinic polymorph of 2-(pyrimidin-2-ylsulfanÂyl)acetic acid
The title compound, C6H6N2O2S, is a new polymorphic form of 2-(pyrimidin-2-ylsulfanÂyl)acetic acid. Unlike the previous orthorhombic polymorph [Pan & Chen (2009 â¶) Acta Cryst. E65, o652], the molÂecules are not planar: the aromatic ring makes an angle of 80.67â
(17)° with the carboxyl plane. In the crystal, molÂecules are linked by OâHâŻN hydrogen bonds into chains along [02]
Wireless sensor network-based solution for environmental monitoring: water quality assessment case study
The challenges of climate change, population growth, demographic change, urbanization and resource depletion mean
that the worldâs great cities need to adapt to survive and thrive over the coming decades. Slashing greenhouse gas emissions to
prevent catastrophic climate change, while maintaining or increasing quality of life, can be a costly and dif cult process. Two
factors that directly affect the life quality in the XXI century cities are the water and air quality that can be monitored using
the combination of low cost sensing modules, machine to machine (M2M) and internet of things (IoT) technologies. In this
context, this study presents a wireless sensor network architecture that combines low cost sensing nodes and a low cost multi-
parameters sensing probe for reliable monitoring of water quality parameters of surface waters (lakes, estuaries and rivers) in
urban areas. A particular attention is dedicated to the design of the conductivity, temperature and turbidity signal conditioning
circuits, highlighting important issues related to linearisation, measuring dynamic range and low-cost implementation by
using commercial off-the-shelf components and devices. Several issues related to the wireless sensor network implementation
are included in this study, as well as several simulation and experimental results.info:eu-repo/semantics/publishedVersio
- âŠ