9 research outputs found
Thermoplastic Polyurethane for Coated Fabrics
- Author
- Publication venue
- 'SAGE Publications'
- Publication date
- Field of study
Reflections on 40 Years of Drug Abuse Prevention Research
- Author
- Publication venue
- 'SAGE Publications'
- Publication date
- Field of study
Structure–Property Relations in Polyurethanes
- Author
- Publication venue
- 'Informa UK Limited'
- Publication date
- Field of study
Health Problems of Epoxy Resins and Amine-curing Agents
- Author
- Publication venue
- 'BMJ'
- Publication date
- Field of study
Breast Prostheses: A Critical Review
- Author
- Andrade J.D.
- Arthur A. Siciliano
- Baldwin C.M.
- Bates H.R.
- Beggs F.D.
- Ben-Hur N.
- Benjamin E.
- Bhat D.J.
- Brand K.G.
- Buchholtz H.W.
- Burri C.
- Coury A.J.
- Dougherty S.H.
- Gahimer F.H.
- Georgiade N.G.
- Hennig E.
- Hester R.T.
- Hester T.R.
- Hester T.R. , Jr.
- Heupner W.C.
- Hollenberg C.
- Hunter G.
- Inoue Von Y.
- Kennedy G.L.
- Kerrigan C.L.
- Kobayashi S.
- Kumagai Y.
- Marchant J.
- Michael Szycher
- Mirra J.M.
- Mitnick J.S.
- Oppenheimer B.S.
- Pedley R.B.
- Pentz W.J.
- Peters W.J.
- Picha G.J.
- Schlebusch L.
- Schmahl D.
- Schmidt R.T.
- Schoen F.J.
- Shipley R.H.
- Siddons A.H.M.
- Sihm F.
- Steven J. Lee
- Van Aken R.
- Whalen R.L.
- Whalen R.L.
- Whidden P.G.
- Wilkins J.
- Publication venue
- 'SAGE Publications'
- Publication date
- Field of study
Neuroendocrine system in lifespan control of Drosophila melanogaster
- Author
- A. Paul
- A. Simonsen
- A.M. Olovnikov
- B. Rogina
- C. Vieira
- D. Crawford
- D.G. Stathakis
- D.J. Clancy
- D.M. Humphrey
- D.S. Hekmat-Scafe
- D.S. Hwangbo
- E.G. Pasyukova
- E.G. Pasyukova
- E.S. Pentz
- F. Martinez-AzorÍn
- G. Morrow
- H. Ruan
- H.D. Wang
- I. Torres-Aleman
- J. Shen
- J. Sun
- J. Sun
- J.H. Bauer
- J.H. Bauer
- J.H. Bauer
- J.H. Bauer
- J.P. Phillips
- K.-J. Min
- K.S. Lee
- K.S. Lee
- L. Connell-Crowley
- M. Landgraf
- M. Miron
- M. Tatar
- M. Whiteley
- M.C. Wang
- M.C. Wang
- M.E. Giannakou
- N.D. Stroumbakis
- N.V. Roshchina
- P.C. Liao
- P.P. Tolias
- Q. Yue
- R. Fernandez
- R.D. Mullen
- R.J. Mockett
- R.J. Mockett
- S. Bboughton
- S. Broughton
- S. Grönke
- S. Kusama
- S. Thor
- S. Thor
- S.D. Katewa
- S.J. Broughton
- S.J. Certel
- S.V. Nuzhdin
- T. Flatt
- T.L. Parkes
- V.I. Pérez
- W. Blenau
- W. Brogiolo
- W.C. Orr
- W.C. Orr
- W.J. Mackay
- Y. Cai
- Y.-W.C. Fridell
- Y.W. Fridell
- Publication venue
- 'Pleiades Publishing Ltd'
- Publication date
- Field of study
Anticoagulant selection in relation to the SAMe-TT2R2 score in patients with atrial fibrillation: The GLORIA-AF registry
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2021
- Field of study
Aim: The SAMe-TT2R2 score helps identify patients with atrial fibrillation (AF) likely to have poor anticoagulation control during anticoagulation with vitamin K antagonists (VKA) and those with scores >2 might be better managed with a target-specific oral anticoagulant (NOAC). We hypothesized that in clinical practice, VKAs may be prescribed less frequently to patients with AF and SAMe-TT2R2 scores >2 than to patients with lower scores. Methods and results: We analyzed the Phase III dataset of the Global Registry on Long-Term Oral Antithrombotic Treatment in Patients with Atrial Fibrillation (GLORIA-AF), a large, global, prospective global registry of patients with newly diagnosed AF and ≥1 stroke risk factor. We compared baseline clinical characteristics and antithrombotic prescriptions to determine the probability of the VKA prescription among anticoagulated patients with the baseline SAMe-TT2R2 score >2 and ≤ 2. Among 17,465 anticoagulated patients with AF, 4,828 (27.6%) patients were prescribed VKA and 12,637 (72.4%) patients an NOAC: 11,884 (68.0%) patients had SAMe-TT2R2 scores 0-2 and 5,581 (32.0%) patients had scores >2. The proportion of patients prescribed VKA was 28.0% among patients with SAMe-TT2R2 scores >2 and 27.5% in those with scores ≤2. Conclusions: The lack of a clear association between the SAMe-TT2R2 score and anticoagulant selection may be attributed to the relative efficacy and safety profiles between NOACs and VKAs as well as to the absence of trial evidence that an SAMe-TT2R2-guided strategy for the selection of the type of anticoagulation in NVAF patients has an impact on clinical outcomes of efficacy and safety. The latter hypothesis is currently being tested in a randomized controlled trial. Clinical trial registration: URL: https://www.clinicaltrials.gov//Unique identifier: NCT01937377, NCT01468701, and NCT01671007. © 2020 Hellenic Society of Cardiolog
Anticoagulant selection in relation to the SAMe-TT2R2 score in patients with atrial fibrillation: The GLORIA-AF registry
- Author
- Abban D.W.
- Abdul N.
- Abud A.M.
- Adams F.
- Addala S.
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- Yamanoue H.
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- Yang T.
- Yao J.
- Yeh K.-H.
- Yin W.H.
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- Zahn R.
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- Zarich S.
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- Zeuthen E.L.
- Zhang D.
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- Zhao S.P.
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- Zhao Z.
- Zheng Y.
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- Zimmermann S.
- Zini A.
- Zizzo S.
- Zong W.
- Zukerman L.S.
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2021
- Field of study
Aim: The SAMe-TT2R2 score helps identify patients with atrial fibrillation (AF) likely to have poor anticoagulation control during anticoagulation with vitamin K antagonists (VKA) and those with scores >2 might be better managed with a target-specific oral anticoagulant (NOAC). We hypothesized that in clinical practice, VKAs may be prescribed less frequently to patients with AF and SAMe-TT2R2 scores >2 than to patients with lower scores. Methods and results: We analyzed the Phase III dataset of the Global Registry on Long-Term Oral Antithrombotic Treatment in Patients with Atrial Fibrillation (GLORIA-AF), a large, global, prospective global registry of patients with newly diagnosed AF and 651 stroke risk factor. We compared baseline clinical characteristics and antithrombotic prescriptions to determine the probability of the VKA prescription among anticoagulated patients with the baseline SAMe-TT2R2 score >2 and 64 2. Among 17,465 anticoagulated patients with AF, 4,828 (27.6%) patients were prescribed VKA and 12,637 (72.4%) patients an NOAC: 11,884 (68.0%) patients had SAMe-TT2R2 scores 0-2 and 5,581 (32.0%) patients had scores >2. The proportion of patients prescribed VKA was 28.0% among patients with SAMe-TT2R2 scores >2 and 27.5% in those with scores 642. Conclusions: The lack of a clear association between the SAMe-TT2R2 score and anticoagulant selection may be attributed to the relative efficacy and safety profiles between NOACs and VKAs as well as to the absence of trial evidence that an SAMe-TT2R2-guided strategy for the selection of the type of anticoagulation in NVAF patients has an impact on clinical outcomes of efficacy and safety. The latter hypothesis is currently being tested in a randomized controlled trial. Clinical trial registration: URL: https://www.clinicaltrials.gov//Unique identifier: NCT01937377, NCT01468701, and NCT01671007
Bibliographische Notizen und Mitteilungen
- Author
- Abdal-Tawab A.R.
- Aerts W.J.
- Aerts W.J.
- Afinogenov D.
- Afinogenov D.
- Afinogenov D.E.
- Agathias Brodka D.
- Ahmet K.
- Airaldi G.
- Aja Sánchez J.R.
- Ajbabin A.I.
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- Al-Tahir G.M.A.
- Alexakis A.
- Alexopoulos S.
- Alfeev Ilarion
- Altripp 0
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- Amarù G.
- Amidon Ph R.
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- 'Walter de Gruyter GmbH'
- Publication date
- Field of study