614 research outputs found
Effective Focal Area Dimension Optimization of Shear Horizontal Point-Focusing EMAT Using Orthogonal Test Method
To overcome the shortcomings of low energy conversion efficiency of electromagnetic acoustic transducers (EMATs), point-focusing shear horizontal (PFSH) wave EMAT is used to focus the wave energy into a specific area. Many factors will affect the capability of the focusing transducer, and in addition to considering the signal intensity, the detection accuracy is also required to be investigated. Specifically, to simplify the test process, we use the orthogonal test method to study the effect of different influence parameters on signal intensity and focal area dimensions. Seven factors are selected, and three results are determined in the test. Range analysis shows that for signal amplitude M , the top three impact factors are the coil width w , coil turns n , and focal length lF (equal to bandwidth factor α ). Moreover, magnet number m and frequency fc dominate the effective focal length lfd , and aperture angle Ξ determines the effective focal width wfd . To enable higher signal intensity and smaller focal area dimensions, it is necessary to consider various factors on the PFSH-EMAT focusing performance. The testâs signal intensity with optimized parametersâ combination at the focal point is nearly 144.42% higher than the average of all the tests, lfd decreased by 37.84%, and wfd decreased by 50.59%. The experiment also verified that focusing EMAT with optimized parameters has a better focusing performance
Defect detection and identification of point-focusing shear-horizontal EMAT for plate inspection
As a kind of nondestructive testing (NDT) method, shear-horizontal (SH)-guided wave detection technology is widely used on an electromagnetic acoustic transducer (EMAT). Although ultrasonic-guided waves perform well in defect location, it is difficult to obtain detailed information about defects, and the low efficiency of EMAT energy conversion still reduces the EMATâs performance. Therefore, in this work, the defect detection method of different shapes and sizes by point-focusing shear-horizontal (PFSH)-guided wave EMAT with the use of periodic permanent magnet (PPM) is investigated through simulation and experiment. For the purpose of defect classification and quantification, the extraction principles of defect features are obtained through simulation based on the circumferential scatter diagrams, and the neural network (NN) is used to process the features extracted from the experimental data. The results show that by extracting effective defect features from the scatter diagram, high-accuracy classification and high-precision quantification of defects under the influence of the focusing transducer can be achieved
Numerical investigation of conjugated heat transfer in a channel with a moving depositing front
This article presents numerical simulations of conjugated heat transfer in a fouled channel with a moving depositing front. The depositing front separating the fluid and the deposit layer is captured using the level-set method. Fluid flow is modeled by the incompressible NavierâStokes equations. Numerical solution is performed on a fixed mesh using the finite volume method. The effects of Reynolds number and thermal conductivity ratio between the deposit layer and the fluid on local Nusselt number as well as length-averaged Nusselt number are investigated. It is found that heat transfer performance, represented by the local and length-averaged Nusselt number reduces significantly in a fouled channel compared with that in a clean channel. Heat transfer performance decreases with the growth of the deposit layer. Increases in Reynolds, Prandtl numbers both enhance heat transfer. Besides, heat transfer is enhanced when the thermal conductivity ratio between the deposit layer and the fluid is lower than 20 but it decreases when the thermal conductivity ratio is larger than 2
International risk of SARS-CoV-2 Omicron variant importations originating in South Africa
Omicron, a fast-spreading SARS-CoV-2 variant of concern reported to the World Health Organization on November 24, 2021, has raised international alarm. We estimated there is at least 50% chance that Omicron had been introduced by travelers from South Africa into all of the 30 countries studied by November 27, 2021.Integrative Biolog
Effects of electrode material and configuration on the characteristics of planar resistive switching devices
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Cyclophosphamide induces NR2B phosphorylation-dependent facilitation on spinal reflex potentiation
Chang CH, Peng HY, Wu HC, Lai CY, Hsieh MC, Lin TB. Cyclophosphamide induces NR2B phosphorylation-dependent facilitation on spinal reflex potentiation. Am J Physiol Renal Physiol 300: F692-F699, 2011. First published November 24, 2010; doi:10.1152/ajprenal.00531.2010.-It is well-established that cyclophosphamide (CYP) can sensitize the pelvic afferent nerve arising from the urinary bladder and therefore induce suprapubic pain. To test the possibility that CYP might mediate the development of visceral hypereflexia/hyperalgesia by facilitating spinal activity-dependent neural plasticity, we compared the pelvic-urethra reflex activity and spinal N-methyl-D-aspartate receptor NR2B subunit (NR2B) phosphorylation in rats treated with vehicle solution and CYP. Compared with vehicle solution, when accompanied by upregulation of phosphorylated NR2B expression in the lumbosacral (L6-S2) dorsal horn, CYP increased the evoked spikes in spinal reflex potentiation induced by repetitive stimulation (1 stimulation/1 s). Moreover, intraperitoneal pretreatments with N(G)-nitro-L-arginine methyl ester and roscovitine, nitric oxide synthase and cyclin-dependent protein kinase 5 (Cdk5) antagonists, respectively, overwrote CYP-enhanced reflex potentiation and NR2B phosphorylation. When compared with the untreated group, the treatment with small-interfering RNA of NR2B, which decreased the expression of NR2B expression, abolished CYP-dependent reflex facilitation and spinal NR2B phosphorylation. These results suggested that CYP might facilitate spinal reflex potentiation mediated by N-methyl-D-aspartate receptors and participate in the development of visceral hypereflexia/hyperalgesia through nitric oxide-and Cdk5-dependent NR2B phosphorylation at the lumbosacral dorsal horn
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International risk of the new variant COVID-19 importations originating in the United Kingdom
A fast-spreading SARS-CoV-2 variant identified in the United Kingdom in December 2020 has raised international alarm. We estimate that, in all 15 countries analyzed, there is at least a 50% chance the variant was imported by travelers from the United Kingdom by December 7th.Financial support was provided by the Health and Medical Research Fund, Food and Health Bureau, Government of the Hong Kong Special Administrative Region (grant no. COVID190118), the US National Institutes of Health (grant no. R01 AI151176) and CDC COVID Supplement (grant no. U01IP001136).Integrative Biolog
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Risk for International Importations of Variant SARS-CoV-2 Originating in the United Kingdom
A fast-spreading severe acute respiratory syndrome coronavirus 2 variant identified in the United Kingdom in December 2020 has raised international alarm. We analyzed data from 15 countries and estimated that the chance that this variant was imported into these countries by travelers from the United Kingdom by December 7 is >50%.Financial support was provided by the Health and Medical Research Fund, Food and Health Bureau, Government of the Hong Kong Special Administrative Region (grant no. COVID190118), the US National Institutes of Health (grant no. R01 AI151176), and Centers for Disease Control and Prevention COVID Supplement (grant no. U01IP001136).Integrative Biolog
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