1,084 research outputs found
Use of ERTS-1 data in the educational and applied research programs of agricultural extension
There are no author-identified significant results in this report
Practical quantum repeaters with linear optics and double-photon guns
We show how to create practical, efficient, quantum repeaters, employing
double-photon guns, for long-distance optical quantum communication. The guns
create polarization-entangled photon pairs on demand. One such source might be
a semiconducter quantum dot, which has the distinct advantage over parametric
down-conversion that the probability of creating a photon pair is close to one,
while the probability of creating multiple pairs vanishes. The swapping and
purifying components are implemented by polarizing beam splitters and
probabilistic optical CNOT gates.Comment: 4 pages, 4 figures ReVTe
Dumbbell transport and deflection in a spatially periodic potential
We present theoretical results on the deterministic and stochastic motion of
a dumbbell carried by a uniform flow through a three-dimensional spatially
periodic potential. Depending on parameters like the flow velocity, there are
two different kinds of movement: transport along a potential valley and
stair-like motion oblique to the potential trenches. The crossover between
these two regimes, as well as the deflection angle, depends on the size of the
dumbbell. Moreover, thermal fluctuations cause a resonance-like variation in
the deflection angle as a function of the dumbbell extension.Comment: 5 pages, 8 figure
Ranking ligand affinity for the DNA minor groove by experiment and simulation
The structural and thermodynamic basis for the strength and selectivity of the interactions of minor-groove binders (MGBs) with DNA is not fully understood. In 2003 we reported the first example of a thiazole containing MGB that bound in a phase shifted pattern that spanned 6 base-pairs rather than the usual 4 (for tricyclic distamycin-like compounds). Since then, using DNA footprinting, nuclear magnetic resonance spectroscopy, isothermal titration calorimetry and molecular dynamics, we have established that the flanking bases around the central 4 being read by the ligand have subtle effects on recognition. We have investigated the effect of these flanking sequences on binding and the reasons for the differences and established a computational method to rank ligand affinity against varying DNA sequences
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User's Guide for MetView: A Meteorological Display and Assessment Tool
MetView Version 2.0 is an easy-to-use model for accessing, viewing, and analyzing meteorological data. MetView provides both graphical and numerical displays of data. It can accommodate data from an extensive meteorological monitoring network that includes near-surface monitoring locations, instrumented towers, sodars, and meteorologist observations. MetView is used operationally for both routine, emergency response, and research applications at the U.S. Department of Energy's Hanford Site. At the Site's Emergency Operations Center, MetView aids in the access, visualization, and interpretation of real-time meteorological data. Historical data can also be accessed and displayed. Emergency response personnel at the Emergency Operations Center use MetView products in the formulation of protective action recommendations and other decisions. In the initial stage of an emergency, MetView can be operated using a very simple, five-step procedure. This first-responder procedure allows non-technical staff to rapidly generate meteorological products and disseminate key information. After first-responder information products are produced, the Emergency Operations Center's technical staff can conduct more sophisticated analyses using the model. This may include examining the vertical variation in winds, assessing recent changes in atmospheric conditions, evaluating atmospheric mixing rates, and forecasting changes in meteorological conditions. This user's guide provides easy-to-follow instructions for both first-responder and routine operation of the model. Examples, with explanations, are provided for each type of MetView output display. Information is provided on the naming convention, format, and contents of each type of meteorological data file used by the model area. This user's guide serves as a ready reference for experienced MetView users and a training manual for new users
Microwave Assisted Synthesis of Py-Im Polyamides
Microwave synthesis was utilized to rapidly build Py-Im polyamides in high yields and purity using Boc-protection chemistry on Kaiser oxime resin. A representative polyamide targeting the 5′-WGWWCW-3′ (W = A or T) subset of the consensus Androgen and Glucocorticoid Response Elements was synthesized in 56% yield after 20 linear steps and HPLC purification. It was confirmed by Mosher amide derivatization of the polyamide that a chiral α-amino acid does not racemize after several additional coupling steps
An entangled two photon source using biexciton emission of an asymmetric quantum dot in a cavity
A semiconductor based scheme has been proposed for generating entangled
photon pairs from the radiative decay of an electrically-pumped biexciton in a
quantum dot. Symmetric dots produce polarisation entanglement, but
experimentally-realised asymmetric dots produce photons entangled in both
polarisation and frequency. In this work, we investigate the possibility of
erasing the `which-path' information contained in the frequencies of the
photons produced by asymmetric quantum dots to recover polarisation-entangled
photons. We consider a biexciton with non-degenerate intermediate excitonic
states in a leaky optical cavity with pairs of degenerate cavity modes close to
the non-degenerate exciton transition frequencies. An open quantum system
approach is used to compute the polarisation entanglement of the two-photon
state after it escapes from the cavity, measured by the visibility of
two-photon interference fringes. We explicitly relate the two-photon visibility
to the degree of Bell-inequality violation, deriving a threshold at which
Bell-inequality violations will be observed. Our results show that an ideal
cavity will produce maximally polarisation-entangled photon pairs, and even a
non-ideal cavity will produce partially entangled photon pairs capable of
violating a Bell-inequality.Comment: 16 pages, 10 figures, submitted to PR
Expanding the Repertoire of Natural Product-Inspired Ring Pairs for Molecular Recognition of DNA
A furan amino acid, inspired by the recently discovered proximicin natural products, was incorporated into the scaffold of a DNA-binding hairpin polyamide. While unpaired oligomers of 2,4-disubstituted furan amino acids show poor DNA-binding activity, furan (Fn) carboxamides paired with N-methylpyrrole (Py) and N-methylimidazole (Im) rings demonstrate excellent stabilization of duplex DNA as well as discrimination of noncognate sequences, consistent with function as a Py mimic according to the Py/Im polyamide pairing rules
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