The f0(1370) controversy from dispersive meson-meson scattering data analyses

We establish the existence of the long-debated $f_0(1370)$ resonance in the dispersive analyses of meson-meson scattering data. For this, we present a novel approach using forward dispersion relations, valid for generic inelastic resonances. We find its pole at $(1245\pm 40)- i\,(300^{+30}_{-70})$ MeV in $\pi\pi$ scattering. We also provide the couplings as well as further checks extrapolating partial-wave dispersion relations or with other continuation methods. A pole at $(1380^{+70}_{-60})-i\,(220^{+80}_{-70})$ MeV also appears in the $\pi\pi\to K\bar K$ data analysis with partial-wave dispersion relations. Despite settling its existence, our model-independent dispersive and analytic methods still show a lingering tension between pole parameters from the $\pi\pi$ and $K\bar K$ channels that should be attributed to data.Comment: 14 pages, 7 figure

Fock space expansion of sigma meson in leading-Nc

We examine the leading-Nc behavior of the masses and transition matrix elements of some low-lying, few-particle configurations in QCD. A truncation of the Fock space produces an effective, symmetric Hamiltonian that we diagonalize. The lowest eigenvalue is identified as the sigma meson if the Hamiltonian is chosen to represent the scalar sector. As an application, the coefficients of the Nc powers are then fit to two-loop Unitarized SU(2) Chiral Perturbation Theory results for the sigma mass and width as a function of the number of colors, and we show that those results can be accommodated using the QCD Nc dependence previously derived for matrix elements, without the need for unnatural parameters or fine tunings. Finally, we show a very preliminary good quality fit, estimating the proportion of tetraquark/molecule-like (dominant), q-anti-q-like (subdominant) and exotic-like (marginal) configurations in the sigma.Comment: 4 pages, 4 figures, Proceedings of QCD10, the 15th High-Energy Physics International Conference on Quantum Chromodynamic

Omecamtiv mecarbil in chronic heart failure with reduced ejection fraction, GALACTIC‐HF: baseline characteristics and comparison with contemporary clinical trials

Aims: The safety and efficacy of the novel selective cardiac myosin activator, omecamtiv mecarbil, in patients with heart failure with reduced ejection fraction (HFrEF) is tested in the Global Approach to Lowering Adverse Cardiac outcomes Through Improving Contractility in Heart Failure (GALACTIC‐HF) trial. Here we describe the baseline characteristics of participants in GALACTIC‐HF and how these compare with other contemporary trials. Methods and Results: Adults with established HFrEF, New York Heart Association functional class (NYHA) ≥ II, EF ≤35%, elevated natriuretic peptides and either current hospitalization for HF or history of hospitalization/ emergency department visit for HF within a year were randomized to either placebo or omecamtiv mecarbil (pharmacokinetic‐guided dosing: 25, 37.5 or 50 mg bid). 8256 patients [male (79%), non‐white (22%), mean age 65 years] were enrolled with a mean EF 27%, ischemic etiology in 54%, NYHA II 53% and III/IV 47%, and median NT‐proBNP 1971 pg/mL. HF therapies at baseline were among the most effectively employed in contemporary HF trials. GALACTIC‐HF randomized patients representative of recent HF registries and trials with substantial numbers of patients also having characteristics understudied in previous trials including more from North America (n = 1386), enrolled as inpatients (n = 2084), systolic blood pressure < 100 mmHg (n = 1127), estimated glomerular filtration rate < 30 mL/min/1.73 m2 (n = 528), and treated with sacubitril‐valsartan at baseline (n = 1594). Conclusions: GALACTIC‐HF enrolled a well‐treated, high‐risk population from both inpatient and outpatient settings, which will provide a definitive evaluation of the efficacy and safety of this novel therapy, as well as informing its potential future implementation

Nueva localidad y características de la población de Acer skutchii Rehder en la Sierra de Manantlán, Jalisco, México

A new locality of Acer skutchii Rehder was registered in the cloud forest of the Sierra de Manantlán, Jalisco, Mexico. This study provides a description of its population structure and floristic associates.Se da a conocer una nueva localidad de Acer skutchii Rehder para México, dentro del bosque mesófilo de montaña de la Sierra de Manantlán, Jalisco, proporcionando información sobre la estructura de la población y las especies arbóreas asociadas

Ultraviolet laser patterning of porous silicon

This work reports on the fabrication of 1D fringed patterns on nanostructured porous silicon (nanoPS) layers (563, 372, and 290nm thick). The patterns are fabricated by phase-mask laser interference using single pulses of an UV excimer laser (193nm, 20ns pulse duration). The method is a single-step and flexible approach to produce a large variety of patterns formed by alternate regions of almost untransformed nanoPS and regions where its surface has melted and transformed into Si nanoparticles (NPs). The role of laser fluence (5-80mJcm-2), and pattern period (6.3-16µm) on pattern features and surface structuring are discussed. The results show that the diameter of Si NPs increases with fluence up to a saturation value of 75nm for a fluence ˜40mJcm-2. In addition, the percentage of transformed to non-transformed region normalized to the pattern period follows similar fluence dependence regardless the period and thus becomes an excellent control parameter. This dependence is fitted within a thermal model that allows for predicting the in-depth profile of the pattern. The model assumes that transformation occurs whenever the laser-induced temperature increase reaches the melting temperature of nanoPS that has been found to be 0.7 of that of crystalline silicon for a porosity of around 79%. The role of thermal gradients across the pattern is discussed in the light of the experimental results and the calculated temperature profiles, and shows that the contribution of lateral thermal flow to melting is not significant for pattern periods =6.3µm

Laser fabrication of porous silicon-based platforms for cell culturing

Postprint (published version

Home Parenteral Nutrition in Spain, 2015. Home and Ambulatory Artificial Nutrition (NADYA) Group report

Aim: To communicate the results of the Spanish Home Parenteral Nutrition (HEN) registry of the NADYA-SENPE group for the year 2015.Material and methods: Data was recorded online by NADYA group collaborators that were responsible of the HPN follow-up from 1st January to 31st December 2015.Results: Two hundred and thirty-six patients with 243 episodes of NPD were recorded from 40 hospitals. This represents a rate of 5.08 patients/million habitants for 2015. The most frequent pathology in adults was other (26.3%) followed by palliative oncological (21.6%). The most common complication was catheter-related sepsis which presented a rate of 0.53 infections/1,000 days of HPN. Sixty-four episodes were finished; the main cause was death (43.7%) and resuming to oral via (32.8%).Conclusions: we find increasing centers and professional partners, responding to the progressively more patients with parenteral nutrition support at home. The main indications for the establishment of NPD and causes termination of treatment remain stable

The Multi-center Evaluation of the Accuracy of the Contrast MEdium INduced Pd/Pa RaTiO in Predicting FFR (MEMENTOFFR) Study

Aims: Adenosine administration is needed for the achievement of maximal hyperaemia fractional flow reserve (FFR) assessment. The objective was to test the accuracy of Pd/Pa ratio registered during submaximal hyperaemia induced by non-ionic contrast medium (contrast FFR [cFFR]) in predicting FFR and comparing it to the performance of resting Pd/Pa in a collaborative registry of 926 patients enrolled in 10 hospitals from four European countries (Italy, Spain, France and Portugal). Methods and results: Resting Pd/Pa, cFFR and FFR were measured in 1,026 coronary stenoses functionally evaluated using commercially available pressure wires. cFFR was obtained after intracoronary injection of contrast medium, while FFR was measured after administration of adenosine. Resting Pd/Pa and cFFR were significantly higher than FFR (0.93±0.05 vs. 0.87±0.08 vs. 0.84±0.08, p<0.001). A strong correlation and a close agreement at Bland-Altman analysis between cFFR and FFR were observed (r=0.90, p<0.001 and 95% CI of disagreement: from-0.042 to 0.11). ROC curve analysis showed an excellent accuracy (89%) of the cFFR cut-off of ?0.85 in predicting an FFR value ?0.80 (AUC 0.95 [95% CI: 0.94-0.96]), significantly better than that observed using resting Pd/Pa (AUC: 0.90, 95% CI: 0.88-0.91; p<0.001). A cFFR/ FFR hybrid approach showed a significantly lower number of lesions requiring adenosine than a resting Pd/ Pa/FFR hybrid approach (22% vs. 44%, p<0.0001). Conclusions: cFFR is accurate in predicting the functional significance of coronary stenosis. This could allow limiting the use of adenosine to obtain FFR to a minority of stenoses with considerable savings of time and costs

TII - Arquitectura y Arte - AR306 - 202101

Descripción: La arquitectura es un juego de luz y sombras, volúmenes y espacios, colores, texturas, materiales, etc., en este curso se introduce al futuro arquitecto en el arte de combinar dichos elementos de un modo creativo y útil, reflejando cómo somos y qué hacemos las personas. Este taller pretende explorar una parte de ese universo, oculto para algunos, y enseñarnos como se puede diseñar algo que luego será parte de nuestro entorno, convirtiendo en realidad algo que nació de la imaginación. Propósito: TII - Arquitectura y Arte es la base indispensable para los talleres siguientes. Se propone introducir al estudiante en el ejercicio del diseño arquitectónico por caminos indirectos, reflexionando sobre algún asunto relativo a la arquitectura (teoría) poniendo énfasis en el arte (concepto) para luego resolver un encargo (práctica). Generalmente estos encargos esconden simples claves que permiten resolver con ingenio y creatividad el desafío. Deben ser desarrollados individualmente o en grupos para compartir ideas, soluciones y responsabilidades en busca del proyecto perfecto. Esta asignatura contribuye directamente al desarrollo de la competencia general de Pensamiento Innovador y la competencia especifica de Diseño fundamentado que corresponde a los criterios NAAB: PC2, PC5, SC5) ambas a un Nivel 1. Sus requisitos son Expresión Artística y Espacia y TI- introducción al Diseño Arquitectónico