2,334 research outputs found

    Hubungan Dukungan Keluarga dengan Tingkat Kecemasan pada Pasien Penyakit Jantung Koroner

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    Angka kejadian penyakit jantung masih nomor satu di dunia, salah satunya penyakit jantung koroner. Pasien yang menderita penyakit jantung memiliki resiko yang dapat membuat penyakitnya semakin parah. Saat seseorang di diagnosa menderita penyakit jantung, respon yang timbul dalam dirinya adalah perasaan cemas dan takut. Dukungan keluarga sangat diperlukan dalam menurunkan tingkat kecemasan pada pasien penyakit jantung koroner. Tujuan dalam penelitian ini adalah menganalisis dukungan keluarga dengan tingkat kecemasan pada pasien penyakit jantung koroner di ruang Wijaya Kusuma RSUD Kota Bekasi Tahun 2015. Desain penelitian ini menggunakan metode deskriptif analitik dengan pendekatan cross sectional, pengambilan sampel dilakukan dengan tehnik puposive sampling yaitu sebanyak 30 responden. Analisa data dilakukan secara bertahap mencakup analisis univariat dan analisis bivariat menggunakan uji statistik chi square. Berdasarkan uji statistik diperoleh nilai p value 0,018 < nilai α 0,05. Sehingga H0 ditolak dan H1 diterima artinya ada hubungan dukungan keluarga dengan tingkat kecemasan pada pasien penyakit jantung koroner di ruang Wijaya Kusuma RSUD Kota Bekasi Tahun 2015

    Lutte contre le tabagisme en Afrique du Sud

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    Versión en inglés disponible en la Biblioteca Digital del IDRC: Economics of tobacco control in South Afric

    HUBUNGAN DUKUNGAN KELUARGA DENGAN TINGKAT KECEMASAN PADA PASIEN PENYAKIT JANTUNG KORONER

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    Angka kejadian penyakit jantung masih nomor satu di dunia, salah satunya penyakit jantung koroner. Pasien yang menderita penyakit jantung memiliki resiko yang dapat membuat penyakitnya semakin parah. Saat seseorang di diagnosa menderita penyakit jantung, respon yang timbul dalam dirinya adalah perasaan cemas dan takut. Dukungan keluarga sangat diperlukan dalam menurunkan tingkat kecemasan pada pasien penyakit jantung koroner. Tujuan dalam penelitian ini adalah menganalisis dukungan keluarga dengan tingkat kecemasan pada pasien penyakit jantung koroner di ruang Wijaya Kusuma RSUD Kota Bekasi Tahun 2015. Desain penelitian ini menggunakan metode deskriptif analitik dengan pendekatan cross sectional, pengambilan sampel dilakukan dengan tehnik puposive sampling yaitu sebanyak 30 responden. Analisa data dilakukan secara bertahap mencakup analisis univariat dan analisis bivariat menggunakan uji statistik chi square. Berdasarkan uji statistik diperoleh nilai p value 0,018 < nilai α 0,05. Sehingga H0 ditolak dan H1 diterima artinya ada hubungan dukungan keluarga dengan tingkat kecemasan pada pasien penyakit jantung koroner di ruang Wijaya Kusuma RSUD Kota Bekasi Tahun 2015

    Determinação de doses de micronutrientes a serem aplicadas via sementes à cultura do feijão (Phaseolus vulgaris L.).

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    O presente trabalho teve como objetivo estudar a aplicação dos micronutrientes Boro (na forma de ácido bórico - H3BO3), Molibdênio (na forma de molibidato de sódio - Na2MoO4) e Cobalto (na forma de sulfato de cobalto - CoSO4) em sementes de feijão, através do processo de recobrimento

    PERSEPSI MASYARAKAT DESA RASAU JAYA UMUM BERDASARKAN INDIKATOR PENGAMATAN TERHADAP KEGIATAN BRIGDALKARHUTMANGGALA AGNI DAOPS PONTIANAK

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    In the forest and land use are many factors that cause the destruction of forests and the land, one of which is the activity of the people who frequent cultivation by burning one of which occurred in the village of Rasau Jaya Umum.. The method used was a survey method with interview-assisted questionnaire. Determination of the number of respondents using Slovin formula and its determination by purposive sampling. Data analysis using Chi Square formula. Public perception Rasau Jaya Umum Village Observations Based Indicators of Activity Against Brigdalkarhut Manggala Agni Daops Pontianak tend to differ. Analysis of the data showed 64.20% of all respondents are neutral, it is because there are some people Rasau Jaya Umum Village felt that the activities carried out by Manggala Agni Brigdalkarhut Daops Pontianak positive impact and people who are active in the burning of land, they have to have eyes other income not related to combustion, burning only do they do at a time when free to grow crops such as corn, pineapple and others,. Independent variables that have a real relationship / significant to the public perception Rasau Jaya Umum Village Observations of activity indicator Brigdalkarhut Manggala Agni Daops Pontianak is the level of age, level of education, cosmopolitan and while that does not have a real relationship / significant is the level of public knowledge. Keywords: Brigdalkarhut Manggala Agni Daops Pontianak, Perception, Public, Rasau Jaya Umum Village

    Comprehensive Model for Physical and Cognitive Frailty: Current Organization and Unmet Needs

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    Aging is characterized by the decline and deterioration of functional cells and results in a wide variety of molecular damages and reduced physical and mental capacity. The knowledge on aging process is important because life expectancy is expected to rise until 2050. Aging cannot be considered a homogeneous process and includes different trajectories characterized by states of fitness, frailty, and disability. Frailty is a dynamic condition put between a normal functional state and disability, with reduced capacity to cope with stressors. This geriatric syndrome affects physical, neuropsychological, and social domains and is driven by emotional and spiritual components. Sarcopenia is considered one of the determinants and the biological substrates of physical frailty. Physical and cognitive frailty are separately approached during daily clinical practice. The concept of motoric cognitive syndrome has partially changed this scenario, opening interesting windows toward future approaches. Thus, the purpose of this manuscript is to provide an excursus on current clinical practice, enforced by aneddoctical cases. The analysis of the current state of the art seems to support the urgent need of comprehensive organizational model incorporating physical and cognitive spheres in the same umbrella

    Altered Thymidine Metabolism Due to Defects of Thymidine Phosphorylase

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    Mitochondrial neurogastrointestinal encephalomyopathy (MNGIE) is an autosomal recessive human disease due to mutations in the thymidine phosphorylase (TP) gene. TP enzyme catalyzes the reversible phosphorolysis of thymidine to thymine and 2-deoxy-D-ribose 1-phosphate. We present evidence that thymidine metabolism is altered in MNGIE. TP activities in buffy coats were reduced drastically in all 27 MNGIE patients compared with 19 controls. All MNGIE patients had much higher plasma levels of thymidine than normal individuals and asymptomatic TP mutation carriers. In two patients, the renal clearance of thymidine was approximately 20% that of creatinine, and because hemodialysis demonstrated that thymidine is ultrafiltratable, most of the filtered thymidine is likely to be reabsorbed by the kidney. In vitro, fibroblasts from controls catabolized thymidine in medium; by contrast, MNGIE fibroblasts released thymidine. In MNGIE, severe impairment of TP enzyme activity leads to increased plasma thymidine. In patients who are suspected of having MNGIE, determination of TP activity in buffy coats and thymidine levels in plasma are diagnostic. We hypothesize that excess thymidine alters mitochondrial nucleoside and nucleotide pools leading to impaired mitochondrial DNA replication, repair, or both. Therapies to reduce thymidine levels may be beneficial to MNGIE patients
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