1,987 research outputs found
Concordant cues in faces and voices: testing the backup signal hypothesis
Information from faces and voices combines to provide multimodal signals about a person. Faces and voices may offer redundant, overlapping (backup signals), or complementary information (multiple messages). This article reports two experiments which investigated the extent to which faces and voices deliver concordant information about dimensions of fitness and quality. In Experiment 1, participants rated faces and voices on scales for masculinity/femininity, age, health, height, and weight. The results showed that people make similar judgments from faces and voices, with particularly strong correlations for masculinity/femininity, health, and height. If, as these results suggest, faces and voices constitute backup signals for various dimensions, it is hypothetically possible that people would be able to accurately match novel faces and voices for identity. However, previous investigations into novel face–voice matching offer contradictory results. In Experiment 2, participants saw a face and heard a voice and were required to decide whether the face and voice belonged to the same person. Matching accuracy was significantly above chance level, suggesting that judgments made independently from faces and voices are sufficiently similar that people can match the two. Both sets of results were analyzed using multilevel modeling and are interpreted as being consistent with the backup signal hypothesis
Dynamic model for failures in biological systems
A dynamic model for failures in biological organisms is proposed and studied
both analytically and numerically. Each cell in the organism becomes dead under
sufficiently strong stress, and is then allowed to be healed with some
probability. It is found that unlike the case of no healing, the organism in
general does not completely break down even in the presence of noise. Revealed
is the characteristic time evolution that the system tends to resist the stress
longer than the system without healing, followed by sudden breakdown with some
fraction of cells surviving. When the noise is weak, the critical stress beyond
which the system breaks down increases rapidly as the healing parameter is
raised from zero, indicative of the importance of healing in biological
systems.Comment: To appear in Europhys. Let
Dynamic model of fiber bundles
A realistic continuous-time dynamics for fiber bundles is introduced and
studied both analytically and numerically. The equation of motion reproduces
known stationary-state results in the deterministic limit while the system
under non-vanishing stress always breaks down in the presence of noise.
Revealed in particular is the characteristic time evolution that the system
tends to resist the stress for considerable time, followed by sudden complete
rupture. The critical stress beyond which the complete rupture emerges is also
obtained
Stevin numbers and reality
We explore the potential of Simon Stevin's numbers, obscured by shifting
foundational biases and by 19th century developments in the arithmetisation of
analysis.Comment: 22 pages, 4 figures. arXiv admin note: text overlap with
arXiv:1104.0375, arXiv:1108.2885, arXiv:1108.420
Uncovering regulatory pathways that affect hematopoietic stem cell function using 'genetical genomics'
We combined large-scale mRNA expression analysis and gene mapping to identify genes and loci that control hematopoietic stem cell (HSC) function. We measured mRNA expression levels in purified HSCs isolated from a panel of densely genotyped recombinant inbred mouse strains. We mapped quantitative trait loci (QTLs) associated with variation in expression of thousands of transcripts. By comparing the physical transcript position with the location of the controlling QTL, we identified polymorphic cis-acting stem cell genes. We also identified multiple trans-acting control loci that modify expression of large numbers of genes. These groups of coregulated transcripts identify pathways that specify variation in stem cells. We illustrate this concept with the identification of candidate genes involved with HSC turnover. We compared expression QTLs in HSCs and brain from the same mice and identified both shared and tissue-specific QTLs. Our data are accessible through WebQTL, a web-based interface that allows custom genetic linkage analysis and identification of coregulated transcripts.
Existence of solutions for a higher order non-local equation appearing in crack dynamics
In this paper, we prove the existence of non-negative solutions for a
non-local higher order degenerate parabolic equation arising in the modeling of
hydraulic fractures. The equation is similar to the well-known thin film
equation, but the Laplace operator is replaced by a Dirichlet-to-Neumann
operator, corresponding to the square root of the Laplace operator on a bounded
domain with Neumann boundary conditions (which can also be defined using the
periodic Hilbert transform). In our study, we have to deal with the usual
difficulty associated to higher order equations (e.g. lack of maximum
principle). However, there are important differences with, for instance, the
thin film equation: First, our equation is nonlocal; Also the natural energy
estimate is not as good as in the case of the thin film equation, and does not
yields, for instance, boundedness and continuity of the solutions (our case is
critical in dimension in that respect)
Information and Computation
In this chapter, concepts related to information and computation are reviewed
in the context of human computation. A brief introduction to information theory
and different types of computation is given. Two examples of human computation
systems, online social networks and Wikipedia, are used to illustrate how these
can be described and compared in terms of information and computation.Comment: 9 pages, 3 figures. Draft of a chapter to be published in Michelucci,
P. (Ed.) Handbook of Human Computation, Springe
Anopheline mosquito saliva contains bacteria that are transferred to a mammalian host through blood feeding
Introduction: Malaria transmission occurs when Plasmodium sporozoites are transferred from the salivary glands of anopheline mosquitoes to a human host through the injection of saliva. The need for better understanding, as well as novel modes of inhibiting, this key event in transmission has driven intense study of the protein and miRNA content of saliva. Until now the possibility that mosquito saliva may also contain bacteria has remained an open question despite the well documented presence of a rich microbiome in salivary glands. MethodsUsing both 16S rRNA sequencing and MALDI-TOF approaches, we characterized the composition of the saliva microbiome of An. gambiae and An. stephensi mosquitoes which respectively represent two of the most important vectors for the major malaria-causing parasites P. falciparum and P. vivax. ResultsTo eliminate the possible detection of non-mosquito-derived bacteria, we used a transgenic, fluorescent strain of one of the identified bacteria, Serratiamarcescens, to infect mosquitoes and detect its presence in mosquito salivary glands as well as its transfer to, and colonization of, mammalian host tissues following a mosquito bite. We also showed that Plasmodium infection modified the mosquito microbiota, increasing the presence of Serratia while diminishing the presence of Elizabethkingia and that both P. berghei and Serratia were transferred to, and colonized mammalian tissues. DiscussionThese data thus document the presence of bacteria in mosquito saliva, their transfer to, and growth in a mammalian host as well as possible interactions with Plasmodium transmission. Together they raise the possible role of mosquitoes as vectors of bacterial infection and the utility of commensal mosquito bacteria for the development of transmission-blocking strategies within a mammalian host
Shear stress fluctuations in the granular liquid and solid phases
We report on experimentally observed shear stress fluctuations in both
granular solid and fluid states, showing that they are non-Gaussian at low
shear rates, reflecting the predominance of correlated structures (force
chains) in the solidlike phase, which also exhibit finite rigidity to shear.
Peaks in the rigidity and the stress distribution's skewness indicate that a
change to the force-bearing mechanism occurs at the transition to fluid
behaviour, which, it is shown, can be predicted from the behaviour of the
stress at lower shear rates. In the fluid state stress is Gaussian distributed,
suggesting that the central limit theorem holds. The fibre bundle model with
random load sharing effectively reproduces the stress distribution at the yield
point and also exhibits the exponential stress distribution anticipated from
extant work on stress propagation in granular materials.Comment: 11 pages, 3 figures, latex. Replacement adds journal reference and
addresses referee comment
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