Development and test of a planar R-band accelerating structure

Planar accelerating structures, so called muffin tins, are of great interest for new accelerating techniques which are operating at high frequencies. At present the upper frequency limit for high power sources is 29.9855 GHz available at CERN. Therefore a new design of a planar traveling wave constant impedance accelerating structure is presented. A fully engineered 37-cell prototype with an operating frequency of 29.9855 GHz, which is designed for the 2 pi /3-mode, was fabricated by CNC milling technology. The design includes a power coupler, a cavity geometry optimized to compensate the effect of transverse forces, vacuum flanges and beam pipe flanges. Shown are the frequency scan of transmission and reflection measurements compared to numerical simulations with GdfidL. Further, a non resonant bead pull measurement was made to determine and verify the fundamental modes of the structure. The cavity is planned to be powered at the CLIC test stand at CERN. (4 refs)

QCD Thermodynamics with Improved Actions

The thermodynamics of the SU(3) gauge theory has been analyzed with tree level and tadpole improved Symanzik actions. A comparison with the continuum extrapolated results for the standard Wilson action shows that improved actions lead to a drastic reduction of finite cut-off effects already on lattices with temporal extent $N_\tau=4$. Results for the pressure, the critical temperature, surface tension and latent heat are presented. First results for the thermodynamics of four-flavour QCD with an improved staggered action are also presented. They indicate similarly large improvement factors for bulk thermodynamics.Comment: Talk presented at LATTICE96(finite temperature) 4 pages, LaTeX2e file, 6 eps-file

UC-Secure OT from LWE, Revisited

We build a two-round, UC-secure oblivious transfer protocol (OT) in the common reference string (CRS) model under the Learning with Errors assumption (LWE) with sub-exponential modulus-to-noise ratio. We do so by instantiating the dual-mode encryption framework of Peikert, Vaikuntanathan and Waters (CRYPTO\u2708). The resulting OT can be instantiated in either one of two modes: one providing statistical sender security, and the other statistical receiver security. Furthermore, our scheme allows the sender and the receiver to reuse the CRS across arbitrarily many executions of the protocol. To the best of our knowledge, this gives the first construction of a UC-secure OT from LWE that achieves both statistical receiver security and unbounded reusability of the CRS. For comparison, there was, until recently, no such construction from LWE satisfying either one of these two properties. In particular, the construction of UC-secure OT from LWE of Peikert, Vaikuntanathan and Waters only provides computational receiver security and bounded reusability of the CRS. Our main technical contribution is a public-key encryption scheme from LWE where messy public keys (under which encryptions hide the underlying message statistically) can be recognized in time essentially independent of the LWE modulus $q$

Chosen-ciphertext security from subset sum

We construct a public-key encryption (PKE) scheme whose security is polynomial-time equivalent to the hardness of the Subset Sum problem. Our scheme achieves the standard notion of indistinguishability against chosen-ciphertext attacks (IND-CCA) and can be used to encrypt messages of arbitrary polynomial length, improving upon a previous construction by Lyubashevsky, Palacio, and Segev (TCC 2010) which achieved only the weaker notion of semantic security (IND-CPA) and whose concrete security decreases with the length of the message being encrypted. At the core of our construction is a trapdoor technique which originates in the work of Micciancio and Peikert (Eurocrypt 2012

Future Challenges and Unsolved Problems in Multi-field Visualization

Evaluation, solved and unsolved problems, and future directions are popular themes pervading the visualization community over the last decade. The top unsolved problem in both scientific and information visualization was the subject of an IEEE Visualization Conference panel in 2004. The future of graphics hardware was another important topic of discussion the same year. The subject of how to evaluate visualization returned a few years later. Chris Johnson published a list of 10 top problems in scientific visualization research. This was followed up by report of both past achievements and future challenges in visualization research as well as financial support recommendations to the National Science Foundation (NSF) and National Institute of Health (NIH). Chen recently published the first list of top unsolved information visualization problems. Future research directions of topology-based visualization was also a major theme of a workshop on topology-based methods. Laramee and Kosara published a list of top future challenges in human-centered visualization

Improved staggered quark actions with reduced flavour symmetry violations for lattice QCD

We introduce a new class of actions for staggered quarks in lattice QCD which significantly reduce flavour symmetry violations in the pion mass spectrum. An action introduced by the MILC collaboration for the same purpose is seen to be a special case. We discus how such actions arise from a systematic attempt to reduce flavour symmetry violations in the weak coupling limit. It is shown that for quenched lattice QCD at 6/g^2=5.7, representative actions of this class give a considerable reduction in flavour symmetry violation over the standard staggered action, and a significant reduction over what is achieved by the MILC action.Comment: RevTeX 18 pages with 3 postscript figure

Targeting lyn kinase in chorea-acanthocytosis: A translational treatment approach in a rare disease

Background: Chorea-acanthocytosis (ChAc) is a neurodegenerative disease caused by mutations in the VPS13A gene. It is characterized by several neurological symptoms and the appearance of acanthocytes. Elevated tyrosine kinase Lyn activity has been recently identified as one of the key pathophysiological mechanisms in this disease, and therefore represents a promising drug target. Methods: We evaluated an individual off-label treatment with the tyrosine kinase inhibitor dasatinib (100 mg/d, 25.8–50.4 weeks) of three ChAc patients. Alongside thorough safety monitoring, we assessed motor and non-motor scales (e.g., MDS-UPDRS, UHDRS, quality of life) as well as routine and experimental laboratory parameters (e.g., serum neurofilament, Lyn kinase activity, actin cytoskeleton in red blood cells). Results: Dasatinib appeared to be reasonably safe. The clinical parameters remained stable without significant improvement or deterioration. Regain of deep tendon reflexes was observed in one patient. Creatine kinase, serum neurofilament levels, and acanthocyte count did not reveal consistent effects. However, a reduction of initially elevated Lyn kinase activity and accumulated autophagy markers, as well as a partial restoration of the actin cytoskeleton, was found in red blood cells. Conclusions: We report on the first treatment approach with disease-modifying intention in ChAc. The experimental parameters indicate target engagement in red blood cells, while clinical effects on the central nervous system could not be proven within a rather short treatment time. Limited knowledge on the natural history of ChAc and the lack of appropriate biomarkers remain major barriers for “clinical trial readiness”. We suggest a panel of outcome parameters for future clinical trials in ChA

Public-Key Encryption Schemes with Auxiliary Inputs

7th Theory of Cryptography Conference, TCC 2010, Zurich, Switzerland, February 9-11, 2010. ProceedingsWe construct public-key cryptosystems that remain secure even when the adversary is given any computationally uninvertible function of the secret key as auxiliary input (even one that may reveal the secret key information-theoretically). Our schemes are based on the decisional Diffie-Hellman (DDH) and the Learning with Errors (LWE) problems. As an independent technical contribution, we extend the Goldreich-Levin theorem to provide a hard-core (pseudorandom) value over large fields.National Science Foundation (U.S.) (Grant CCF-0514167)National Science Foundation (U.S.) (Grant CCF-0635297)National Science Foundation (U.S.) (Grant NSF-0729011)Israel Science Foundation (700/08)Chais Family Fellows Progra

Large FHE Gates from tensored homomorphic accumulator

The main bottleneck of all known Fully Homomorphic Encryption schemes lies in the bootstrapping procedure invented by Gentry (STOC’09). The cost of this procedure can be mitigated either using Homomorphic SIMD techniques, or by performing larger computation per bootstrapping procedure.In this work, we propose new techniques allowing to perform more operations per bootstrapping in FHEW-type schemes (EUROCRYPT’13). While maintaining the quasi-quadratic Õ(n2) complexity of the whole cycle, our new scheme allows to evaluate gates with Ω(log n) input bits, which constitutes a quasi-linear speed-up. Our scheme is also very well adapted to large threshold gates, natively admitting up to Ω(n) inputs. This could be helpful for homomorphic evaluation of neural networks.Our theoretical contribution is backed by a preliminary prototype implementation, which can perform 6-to-6 bit gates in less than 10s on a single core, as well as threshold gates over 63 input bits even faster.<p

Influence of the U(1)_A Anomaly on the QCD Phase Transition

The SU(3)_{r} \times SU(3)_{\ell} linear sigma model is used to study the chiral symmetry restoring phase transition of QCD at nonzero temperature. The line of second order phase transitions separating the first order and smooth crossover regions is located in the plane of the strange and nonstrange quark masses. It is found that if the U(1)_{A} symmetry is explicitly broken by the U(1)_{A} anomaly then there is a smooth crossover to the chirally symmetric phase for physical values of the quark masses. If the U(1)_{A} anomaly is absent, then there is a phase transition provided that the \sigma meson mass is at least 600 MeV. In both cases, the region of first order phase transitions in the quark mass plane is enlarged as the mass of the \sigma meson is increased.Comment: 5 pages, 3 figures, Revtex, discussion extended and references added. To appear in PR