198 research outputs found
Algebro-Geometric Solutions of the Boussinesq Hierarchy
We continue a recently developed systematic approach to the Bousinesq (Bsq)
hierarchy and its algebro-geometric solutions. Our formalism includes a
recursive construction of Lax pairs and establishes associated
Burchnall-Chaundy curves, Baker-Akhiezer functions and Dubrovin-type equations
for analogs of Dirichlet and Neumann divisors. The principal aim of this paper
is a detailed theta function representation of all algebro-geometric
quasi-periodic solutions and related quantities of the Bsq hierarchy.Comment: LaTeX, 48 page
A dimension-breaking phenomenon for water waves with weak surface tension
It is well known that the water-wave problem with weak surface tension has
small-amplitude line solitary-wave solutions which to leading order are
described by the nonlinear Schr\"odinger equation. The present paper contains
an existence theory for three-dimensional periodically modulated solitary-wave
solutions which have a solitary-wave profile in the direction of propagation
and are periodic in the transverse direction; they emanate from the line
solitary waves in a dimension-breaking bifurcation. In addition, it is shown
that the line solitary waves are linearly unstable to long-wavelength
transverse perturbations. The key to these results is a formulation of the
water wave problem as an evolutionary system in which the transverse horizontal
variable plays the role of time, a careful study of the purely imaginary
spectrum of the operator obtained by linearising the evolutionary system at a
line solitary wave, and an application of an infinite-dimensional version of
the classical Lyapunov centre theorem.Comment: The final publication is available at Springer via
http://dx.doi.org/10.1007/s00205-015-0941-
Perceptions and evaluations of front-line health workers regarding the Brazilian National Program for Improving Access and Quality to Primary Care (PMAQ): a mixed-method approach
Although it is well known that a successful implementation depends on the front-liners’ knowledge and participation, as well as on the organizational capacity of the institutions involved, we still know little about how front-line health workers have been involved in the implementation of the Brazilian National Program for Improving Access and Quality to Primary Care (PMAQ). This paper develops a contingent mixed-method approach to explore the perceptions of front-line health workers - managers, nurses, community health workers, and doctors - regarding the PMAQ (2nd round), and their evaluations concerning health unit organizational capacity. The research is guided by three relevant inter-related concepts from implementation theory: policy knowledge, participation, and organizational capacity. One hundred and twenty-seven health workers from 12 primary health care units in Goiânia, Goiás State, Brazil, answered semi-structured questionnaires, seeking to collect data on reasons for adherence, forms of participation, perceived impact (open-ended questions), and evaluation of organizational capacity (score between 0-10). Content analyses of qualitative data enabled us to categorize the variables “level of perceived impact of PMAQ” and “reasons for adhering to PMAQ”. The calculation and aggregation of the means for the scores given for organizational capacity enabled us to classify distinct levels of organizational capacity. We finally integrated both variables (Perceived-Impact and Organizational-Capacity) through cross-tabulation and the narrative. Results show that nurses are the main type of professional participating. The low organizational capacity and little policy knowledge affected workers participation in and their perceptions of the PMAQ
Spectral stability of noncharacteristic isentropic Navier-Stokes boundary layers
Building on work of Barker, Humpherys, Lafitte, Rudd, and Zumbrun in the
shock wave case, we study stability of compressive, or "shock-like", boundary
layers of the isentropic compressible Navier-Stokes equations with gamma-law
pressure by a combination of asymptotic ODE estimates and numerical Evans
function computations. Our results indicate stability for gamma in the interval
[1, 3] for all compressive boundary-layers, independent of amplitude, save for
inflow layers in the characteristic limit (not treated). Expansive inflow
boundary-layers have been shown to be stable for all amplitudes by Matsumura
and Nishihara using energy estimates. Besides the parameter of amplitude
appearing in the shock case, the boundary-layer case features an additional
parameter measuring displacement of the background profile, which greatly
complicates the resulting case structure. Moreover, inflow boundary layers turn
out to have quite delicate stability in both large-displacement and
large-amplitude limits, necessitating the additional use of a mod-two stability
index studied earlier by Serre and Zumbrun in order to decide stability
Stability of a Nonequilibrium Interface in a Driven Phase Segregating System
We investigate the dynamics of a nonequilibrium interface between coexisting
phases in a system described by a Cahn-Hilliard equation with an additional
driving term. By means of a matched asymptotic expansion we derive equations
for the interface motion. A linear stability analysis of these equations
results in a condition for the stability of a flat interface. We find that the
stability properties of a flat interface depend on the structure of the driving
term in the original equation.Comment: 14 pages Latex, 1 postscript-figur
Nonlinear localized waves in a periodic medium
We analyze the existence and stability of nonlinear localized waves in a
periodic medium described by the Kronig-Penney model with a nonlinear defect.
We demonstrate the existence of a novel type of stable nonlinear band-gap
localized states, and also reveal an important physical mechanism of the
oscillatory wave instabilities associated with the band-gap resonances.Comment: 4 pages, 5 figure
Importância prognóstica do alelo CYP2C19*2 após uma síndrome coronária aguda: dados de um centro nacional
BACKGROUND: Clopidogrel requires oxidation dependent on the cytochrome P450 enzyme 2C19 (CYP2C19) to form its active metabolite. The importance of loss-of-function alleles (particularly CYP2C19*2, 681G>A) in poor platelet response to clopidogrel is well recognized.
OBJECTIVE: To investigate the prevalence and prognostic impact of the CYP2C19*2 allele in a local acute coronary syndrome (ACS) population.
METHODS: We performed a prospective, longitudinal study of 95 patients admitted for an ACS between March and October 2009 to a single coronary care unit. Patients aged under 75 who survived hospital stay and for whom clopidogrel was prescribed were included. At discharge, CYP2C19 was genotyped using a commercially available kit. Patients were divided into two groups: Group A (non-carriers, normal metabolizers, CYP2C19*1/*1), n=69; and Group B (carriers, slow metabolizers, CYP2C19*2/*1 or *2/*2), n=26. The primary endpoint was a combined outcome of cardiovascular death, non-fatal myocardial infarction or re-admission for unstable angina; median follow-up was 136.0 (79.0-188.0) days.
RESULTS: The median age of the population was 62.0 (51.0-68.0) years, and 83.2% were male. The CYP2C19*2 (A) allele had a frequency of 14.2%. There were no differences between the groups with respect to demographic data or history of cardiovascular disease. Coronary anatomy, left ventricular ejection fraction and renal function were also similar. The groups were also homogenous with respect to GRACE risk score (118.0 (95.0-136.5) vs. 115.0 (96.0-133.0), p=0.68), medical treatment and percutaneous revascularization during hospital stay. Event-free survival was higher for Group A (94.0% vs. 75.0%, log-rank p=0.010). Three readmissions for MI were documented, all in the slow metabolizers group.
CONCLUSION: In our ACS population, the CYP2C19*2 allele was a medium-term prognostic marker
The phase shift of line solitons for the KP-II equation
The KP-II equation was derived by [B. B. Kadomtsev and V. I.
Petviashvili,Sov. Phys. Dokl. vol.15 (1970), 539-541] to explain stability of
line solitary waves of shallow water. Stability of line solitons has been
proved by [T. Mizumachi, Mem. of vol. 238 (2015), no.1125] and [T. Mizumachi,
Proc. Roy. Soc. Edinburgh Sect. A. vol.148 (2018), 149--198]. It turns out the
local phase shift of modulating line solitons are not uniform in the transverse
direction. In this paper, we obtain the -bound for the local phase
shift of modulating line solitons for polynomially localized perturbations
Instabilities of Higher-Order Parametric Solitons. Filamentation versus Coalescence
We investigate stability and dynamics of higher-order solitary waves in
quadratic media, which have a central peak and one or more surrounding rings.
We show existence of two qualitatively different behaviours. For positive phase
mismatch the rings break up into filaments which move radially to initial ring.
For sufficient negative mismatches rings are found to coalesce with central
peak, forming a single oscillating filament.Comment: 5 pages, 7 figure
Normal scaling in globally conserved interface-controlled coarsening of fractal clusters
Globally conserved interface-controlled coarsening of fractal clusters
exhibits dynamic scale invariance and normal scaling. This is demonstrated by a
numerical solution of the Ginzburg-Landau equation with a global conservation
law. The sharp-interface limit of this equation is volume preserving motion by
mean curvature. The scaled form of the correlation function has a power-law
tail accommodating the fractal initial condition. The coarsening length
exhibits normal scaling with time. Finally, shrinking of the fractal clusters
with time is observed. The difference between global and local conservation is
discussed.Comment: 4 pages, 3 eps figure
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