186 research outputs found

    Quasi-Newtonian dust cosmologies

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    Exact dynamical equations for a generic dust matter source field in a cosmological context are formulated with respect to a non-comoving Newtonian-like timelike reference congruence and investigated for internal consistency. On the basis of a lapse function NN (the relativistic acceleration scalar potential) which evolves along the reference congruence according to N˙=αΘN\dot{N} = \alpha \Theta N (α=const\alpha = {const}), we find that consistency of the quasi-Newtonian dynamical equations is not attained at the first derivative level. We then proceed to show that a self-consistent set can be obtained by linearising the dynamical equations about a (non-comoving) FLRW background. In this case, on properly accounting for the first-order momentum density relating to the non-relativistic peculiar motion of the matter, additional source terms arise in the evolution and constraint equations describing small-amplitude energy density fluctuations that do not appear in similar gravitational instability scenarios in the standard literature.Comment: 25 pages, LaTeX 2.09 (10pt), to appear in Classical and Quantum Gravity, Vol. 15 (1998

    The dynamics of cosmological perturbations in thermal λϕ4\lambda\phi^4 theory

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    Using a recent thermal-field-theory approach to cosmological perturbations, the exact solutions that were found for collisionless ultrarelativistic matter are generalized to include the effects from weak self-interactions in a λϕ4\lambda\phi^4 model through order λ3/2\lambda^{3/2}. This includes the effects of a resummation of thermal masses and associated nonlocal gravitational vertices, thus going far beyond classical kinetic theory. Explicit solutions for all the scalar, vector, and tensor modes are obtained for a radiation-dominated Einstein-de Sitter model containing a weakly interacting scalar plasma with or without the admixture of an independent component of perfect radiation fluid.Comment: 32 pages, REVTEX, 13 postscript figures included by epsf.st

    Respiratory syncytial virus infection activates IL-13–producing group 2 innate lymphoid cells through thymic stromal lymphopoietin

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    BACKGROUND: Respiratory syncytial virus (RSV) is a major health care burden with a particularly high worldwide morbidity and mortality rate among infants. Data suggest that severe RSV-associated illness is in part caused by immunopathology associated with a robust type 2 response. OBJECTIVE: We sought to determine the capacity of RSV infection to stimulate group 2 innate lymphoid cells (ILC2s) and the associated mechanism in a murine model. METHODS: Wild-type (WT) BALB/c, thymic stromal lymphopoietin receptor (TSLPR) knockout (KO), or WT mice receiving an anti-TSLP neutralizing antibody were infected with the RSV strain 01/2-20. During the first 4 to 6 days of infection, lungs were collected for evaluation of viral load, protein concentration, airway mucus, airway reactivity, or ILC2 numbers. Results were confirmed with 2 additional RSV clinical isolates, 12/11-19 and 12/12-6, with known human pathogenic potential. RESULTS: RSV induced a 3-fold increase in the number of IL-13-producing ILC2s at day 4 after infection, with a concurrent increase in total lung IL-13 levels. Both thymic stromal lymphopoietin (TSLP) and IL-33 levels were increased 12 hours after infection. TSLPR KO mice did not mount an IL-13-producing ILC2 response to RSV infection. Additionally, neutralization of TSLP significantly attenuated the RSV-induced IL-13-producing ILC2 response. TSLPR KO mice displayed reduced lung IL-13 protein levels, decreased airway mucus and reactivity, attenuated weight loss, and similar viral loads as WT mice. Both 12/11-19 and 12/12-6 similarly induced IL-13-producing ILC2s through a TSLP-dependent mechanism. CONCLUSION: These data demonstrate that multiple pathogenic strains of RSV induce IL-13-producing ILC2 proliferation and activation through a TSLP-dependent mechanism in a murine model and suggest the potential therapeutic targeting of TSLP during severe RSV infection

    Clues from nearby galaxies to a better theory of cosmic evolution

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    The great advances in the network of cosmological tests show that the relativistic Big Bang theory is a good description of our expanding universe. But the properties of nearby galaxies that can be observed in greatest detail suggest a still better theory would more rapidly gather matter into galaxies and groups of galaxies. This happens in theoretical ideas now under discussion.Comment: published in Natur

    Large Scale Structure of the Universe

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    Galaxies are not uniformly distributed in space. On large scales the Universe displays coherent structure, with galaxies residing in groups and clusters on scales of ~1-3 Mpc/h, which lie at the intersections of long filaments of galaxies that are >10 Mpc/h in length. Vast regions of relatively empty space, known as voids, contain very few galaxies and span the volume in between these structures. This observed large scale structure depends both on cosmological parameters and on the formation and evolution of galaxies. Using the two-point correlation function, one can trace the dependence of large scale structure on galaxy properties such as luminosity, color, stellar mass, and track its evolution with redshift. Comparison of the observed galaxy clustering signatures with dark matter simulations allows one to model and understand the clustering of galaxies and their formation and evolution within their parent dark matter halos. Clustering measurements can determine the parent dark matter halo mass of a given galaxy population, connect observed galaxy populations at different epochs, and constrain cosmological parameters and galaxy evolution models. This chapter describes the methods used to measure the two-point correlation function in both redshift and real space, presents the current results of how the clustering amplitude depends on various galaxy properties, and discusses quantitative measurements of the structures of voids and filaments. The interpretation of these results with current theoretical models is also presented.Comment: Invited contribution to be published in Vol. 8 of book "Planets, Stars, and Stellar Systems", Springer, series editor T. D. Oswalt, volume editor W. C. Keel, v2 includes additional references, updated to match published versio

    A cosmological constant from degenerate vacua

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    Under the hypothesis that the cosmological constant vanishes in the true ground state with lowest possible energy density, we argue that the observed small but finite vacuum-like energy density can be explained if we consider a theory with two or more degenerate perturbative vacua, which are unstable due to quantum tunneling, and if we still live in one of such states. An example is given making use of the topological vacua in non-Abelian gauge theories.Comment: 8 pages, no figur

    Adiabatic and entropy perturbations propagation in a bouncing Universe

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    By studying some bouncing universe models dominated by a specific class of hydrodynamical fluids, we show that the primordial cosmological perturbations may propagate smoothly through a general relativistic bounce. We also find that the purely adiabatic modes, although almost always fruitfully investigated in all other contexts in cosmology, are meaningless in the bounce or null energy condition (NEC) violation cases since the entropy modes can never be neglected in these situations: the adiabatic modes exhibit a fake divergence that is compensated in the total Bardeen gravitational potential by inclusion of the entropy perturbations.Comment: 25 pages, no figure, LaTe

    Measuring our universe from galaxy redshift surveys

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    Galaxy redshift surveys have achieved significant progress over the last couple of decades. Those surveys tell us in the most straightforward way what our local universe looks like. While the galaxy distribution traces the bright side of the universe, detailed quantitative analyses of the data have even revealed the dark side of the universe dominated by non-baryonic dark matter as well as more mysterious dark energy (or Einstein's cosmological constant). We describe several methodologies of using galaxy redshift surveys as cosmological probes, and then summarize the recent results from the existing surveys. Finally we present our views on the future of redshift surveys in the era of Precision Cosmology.Comment: 82 pages, 31 figures, invited review article published in Living Reviews in Relativity, http://www.livingreviews.org/lrr-2004-
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