e-Learning del razonamiento clínico basado en casos en la patología osteoarticular para el grado de Medicina

El objetivo principal del proyecto es el desarrollo de una aplicación on-line dentro de la plataforma PRADO de la Universidad de Granada para implementar el aprendizaje del razonamiento clínico basado en casos para los alumnos de las asignaturas de patología del aparato locomotor de los Grados Fisioterapia y Medicina, y comparar los resultados con la fórmula tradicional de impartir la docencia basada en clases magistrales.The main objective of the project is the development of an online application within the PRADO platform of the University of Granada to implement the learning of clinical reasoning based on cases for the students of the subjects of pathology of the locomotor system of the Degrees Physiotherapy and Medicine, and compare the results with the traditional formula of teaching based on lecture

Yield Components in Annual Ryegrass and Oats Grown in Association and Monoculture

Earliness of oats and higher growth rate of annual ryegrass later in the season explain the higher forage yield of annual ryegrass+oats association over monocultures (Améndola & Morales, 1997). However, changes in yield components of the species grown in association compared to monoculture have not been explored. This study aimed to determine leaf, stem and dead matter yield in annual ryegrass and oats when grown in association and monoculture at different nitrogen (N) levels

Síntesis y caracterización del sistema N - (o-nitrofenil)maleimida

En búsqueda de la obtención de nuevos compuestos con aplicabilidad en fármacos y polímeros, se obtuvo la N-(o-nitrofenil)maleimida (C10H6N2O4). El compuesto se sintetizó mediante la reacción entre el anhídrido maleico y la onitroanilina en agitación con éter dietílico por tres horas, obteniéndose un sólido de color amarillo con punto de fusión de 274 ºC, soluble en acetona. Para verificar su estructura se realizo análisis espectroscópico de RMN 1H, 13C y COSY. En el espectro de RMN 1H se encontraron señales de desplazamiento a 8.3, 7.4 y 6.8 ¿. En el espectro de masas se observó el pico molecular de 218 g/mol. En el espectro de IR se observó una banda a 1711.70 cm-1 y el espectro UV-VIS manifestó un desplazamiento de la banda del cromóforo de los precursores con el compuesto.In search of the obtaining of new compound up with applicability in pharmaco and polymers, the N-(o-nitrofenil)maleimide was obtained (C10H6N2O4). The compound is synthesizes with the reaction among the maleic anhydride and onitroanilina in agitation with ether diethilic for three hours, being obtained a solid of yellow color with melting point of 274 ºC, soluble in acetone, to verify its structure one carries out analysis spectroscópic of RMN 1H, 13C and COSY showing the signs at 8.3, 7.4 and 6.8 approximately in the RMN 1H. Spectroscopic of Masses obtained a molecular pick of 218 g/mol. Spectrum IR with band to 1711.70 cm-1 and spectrum UV-VIS manifest displacement chromofor`s band of the precursors with the compound

Uses of Native Plant Species of a Communal Rangeland within ‘Sierra de Huautla’ Protected Area, México

Sustainability of communal rangelands has become a major concern at national and international levels because land use conflicts and associated social conflicts allows for over-utilization of selected species making a high pressure on them and given away their places to species with no use at all becoming lands degraded and unproductive. The objective of the study was to determine floristic composition and native plant uses by local peasants. The range surface is of 4262 ha, belongs to the communal land ‘El Limon’, in Tepalcingo, Morelos, Mexico, and it is within the Natural Reserve Area “Sierra de Huautla”. Native vegetation is mainly of deciduous shrubs, high temperatures year round and a rainy season of 4 months. Local peasants were surveyed on uses of the collected and previously identified plants. Number of species was 456, distributed in 266 and 76 botanical genders and families, respectively. Of the species identified 66, 22 and 12% had one, two or more than two uses according to local peasants. Among uses: 59% of the species were used as forage, 8% eatable, 7% firewood or ornamental, 6% medical herb, lumber or other use 4 %, construction material 3 % and for resin or handcraft 1%. The range showed a very high plant biodiversity, this feature allows for a high resiliency toward human activities

Sauvé-Kapandji and reverse Sauvé-Kapandji procedures for treating chronic longitudinal radioulnar dissociation with capitellum fracture

Almost all reported cases of longitudinal radioulnar dissociation have involved fracture of the radial head, rupture of the interosseous membrane, and disruption of the distal radioulnar joint, although unusual patterns of Essex-Lopresti injury have also been described. To our knowledge, this is the first report of a chronic Essex-Lopresti variant including fracture of the capitellum. A displaced capitellum fracture must alert to the possibility of longitudinal radioulnar dissociation, even without concomitant radial head fracture or symptoms at the forearm and ulnar wrist. Successful mid-term results can be achieved by treating malunion of humeral condyle and proximal migration of the radius with simultaneous Sauvé-Kapandji procedure at the wrist and reverse Sauvé-Kapandji at the elbow.Essex-Lopresti lezyonlarının nadir görülen bazı atipik formları tanımlanmış olsa da, literatürde bildirilen longitudinal radioulnar instabilite olgularında genellikle radius başı kırığı ve proksimal ve distal radioulnar eklemlerde yaralanma söz konusudur. Bu çalışmada kapitellum kırığı ile birlikte Essex- Lopresti lezyonu olan bir hastayı bildiriyoruz. Olgumuzda el bileğinde Sauvé-Kapandji ve dirsekte ters Sauvé-Kapandji tekniklerinin kombine olarak uygulanması ile orta vadede başarılı sonuçlar alınmıştır. El bileği ve önkol yakınması olmasa bile deplase kapitellum kırıklı hastalarda longitudinal radioulnar instabilite akla getirilmelidir

On-Offer and Residual Forage in a Massai-\u3cem\u3eLeucaena\u3c/em\u3e Pasture at Different Leucaena Density

Mexican livestock producers in tropical areas are increasingly interested on the establishment of silvopastoral systems based on Leucaena (Leucaena leucocephala (Lam.) de Wit) and different tropical grasses as the Massai grass (Panicum maximum cv Massai); among questions raised on this is the importance of Leucaena density in relation to forage available. Then the objective of the study was to determine total and by species on-offer and residual forage in a grazed MassaiLeucaena pasture with different Leucaena density

Metabolomics and biochemical approaches link salicylic acid biosynthesis to cyanogenesis in peach plants

Despite the long-established importance of salicylic acid (SA) in plant stress responses and other biological processes, its biosynthetic pathways have not been fully characterized. The proposed synthesis of SA originates from chorismate by two distinct pathways: the isochorismate and phenylalanine (Phe) ammonia-lyase (PAL) pathways. Cyanogenesis is the process related to the release of hydrogen cyanide from endogenous cyanogenic glycosides (CNglcs), and it has been linked to plant plasticity improvement. To date, however, no relationship has been suggested between the two pathways. In this work, by metabolomics and biochemical approaches (including the use of [C-13]-labeled compounds), we provide strong evidences showing that CNglcs turnover is involved, at least in part, in SA biosynthesis in peach plants under control and stress conditions. The main CNglcs in peach are prunasin and amygdalin, with mandelonitrile (MD), synthesized from phenylalanine, controlling their turnover. In peach plants MD is the intermediary molecule of the suggested new SA biosynthetic pathway and CNglcs turnover, regulating the biosynthesis of both amygdalin and SA. MD-treated peach plants displayed increased SA levels via benzoic acid (one of the SA precursors within the PAL pathway). MD also provided partial protection against Plum pox virus infection in peach seedlings. Thus, we propose a third pathway, an alternative to the PAL pathway, for SA synthesis in peach plantsThis work was supported by the Spanish Ministry of Economy and Competitiveness (Project AGL2014-52563-R). PDV and CP thank CSIC and UPCT, respectively, as well as the Spanish Ministry of Economy and Competitiveness for their ‘Ramon & Cajal’ research contract, co-financed by FEDER funds. We also acknowledge Prof. Manuel Acosta Echeverría for his very useful commentaries and discussion

Description of \u3cem\u3eLeucaena\u3c/em\u3e On-Offer Browse at Different \u3cem\u3eLeucaena\u3c/em\u3e Density

Leucaena (Lecuaena lecucephala (Lam.) de Wit) is a tree legume widely used to establish silvopastoral systems along with different tropical grasses. The relation of Leucaena density to browse available at the start of each grazing period in a rotational grazing management is important information when designing a silvopastoral pasture (Anguiano et al., 2013). Then the objective of the study was to determine Leucaena on-offer browse at different Leucaena density

Slow Resorption of Anorganic Bovine Bone by Osteoclasts in Maxillary Sinus Augmentation

Purpose: Different biomaterials have been suggested for guided bone regeneration (GBR). These might show the ideal properties to let a new bone formation in the grafted area. Among these ideal features, it is essential their controlled resorption in order to be replaced for new vital bone. Bovine bone has been used widely as a good biomaterial for GBR, however there is still an interesting controversy about its resorbable capacity. In this sense, the objective of this study was to examine the behavior of anorganic bovine bone (ABB) in long‐term maxillary sinus graft healing and study its relationship with morphological and morphometrical variables. Materials and Methods: Seventeen maxillary sinus augmentation procedures were performed in patients. Bone cores were obtained from implant receptor sites at 6 months, 3 years, and 7 years of implant placement for histological, morphometric, and immunohistochemical (tartrate resistant acid phosphatase [TRAP]/cathepsin K/CD68) studies. Results: The percentages of bone, ABB particles, connective tissue, osteocytes, and osteoblasts in maxillary sinus grafts were similar at 6 months, 3 years, and 7 years. A progressive and significant decrease was detected in osteoclasts ( p  = .05, Kruskal‐Wallis test), TRAP and cathepsin K expression ( p  = .014 and p  = .021, respectively), and osteoid lines ( p  = .038). Conclusion: According to these data, a decrease in osteoclasts over time may, partially, explain the ABB persistence observed in core biopsies. Further studies with more cases and different graft maturation times are required to elucidate the resorption rates and cell events underlying these phenomena.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/101852/1/cid445.pd