64 research outputs found
Evaluation of spatial and temporal variability of pasture based on topography and the quality of the rainy season
Yield and botanical composition of a given dry-land pasture are heavily influenced by rainfall distribution, and vary according to topography. Through analyzing these parameters, it is possible to identify patterns of spatial distribution, related to
topographic characteristics, which can be used to improve spatial management of pasture.
The main objective of this project was to assess the role of rainfall, temperature and
topography in the spatial and temporal variability of pasture and establish models for predicting the spatial distribution and yield of certain plant species, based on its topographic characteristics. This study was carried out over three years, 2004 to 2006, in a dryland
pasture located in Southern Portugal. The data obtained were analyzed as a function of
distance to flow lines and the results demonstrate that certain topographical characteristics,
associated with agronomic information, can be very useful in explaining the spatial and
temporal variability of yield and the botanical composition of the pasture. The slope of the linear regression of the variables mentioned can be used to estimate the spatial variation of
yield and the botanical composition as a function of distance to flow lines. The regression coefficient can be estimated from the annual rainfall, given the strong correlation between the two
Thermodynamics of Reissner-Nordstrom-anti-de Sitter black holes in the grand canonical ensemble
The thermodynamical properties of the Reissner-Nordstr\"om-anti-de Sitter
black hole in the grand canonical ensemble are investigated using York's
formalism. The black hole is enclosed in a cavity with finite radius where the
temperature and electrostatic potential are fixed. The boundary conditions
allow us to compute the relevant thermodynamical quantities, e.g. thermal
energy, entropy and charge. The stability conditions imply that there are
thermodynamically stable black hole solutions, under certain conditions.
Instantons with negative heat capacity are also found.Comment: 15 pages, 9 figures, Revtex. Published version. Changes: figures
added to tex
Thermodynamics of Kerr-Newman-AdS Black Holes and Conformal Field Theories
We study the thermodynamics of four-dimensional Kerr-Newman-AdS black holes
both in the canonical and the grand-canonical ensemble. The stability
conditions are investigated, and the complete phase diagrams are obtained,
which include the Hawking-Page phase transition in the grand-canonical
ensemble. In the canonical case, one has a first order transition between small
and large black holes, which disappears for sufficiently large electric charge
or angular momentum. This disappearance corresponds to a critical point in the
phase diagram. Via the AdS/CFT conjecture, the obtained phase structure is also
relevant for the corresponding conformal field theory living in a rotating
Einstein universe, in the presence of a global background U(1) current. An
interesting limit arises when the black holes preserve some supersymmetry.
These BPS black holes correspond to highly degenerate zero temperature states
in the dual CFT, which lives in an Einstein universe rotating with the speed of
light.Comment: 27 pages, RevTeX, 12 ps figures. Minor changes, references added.
Final version to appear in Class. Quantum Gra
SHANK3 controls maturation of social reward circuits in the VTA.
Haploinsufficiency of SHANK3, encoding the synapse scaffolding protein SHANK3, leads to a highly penetrant form of autism spectrum disorder. How SHANK3 insufficiency affects specific neural circuits and how this is related to specific symptoms remains elusive. Here we used shRNA to model Shank3 insufficiency in the ventral tegmental area of mice. We identified dopamine (DA) and GABA cell-type-specific changes in excitatory synapse transmission that converge to reduce DA neuron activity and generate behavioral deficits, including impaired social preference. Administration of a positive allosteric modulator of the type 1 metabotropic glutamate receptors mGluR1 during the first postnatal week restored DA neuron excitatory synapse transmission and partially rescued the social preference defects, while optogenetic DA neuron stimulation was sufficient to enhance social preference. Collectively, these data reveal the contribution of impaired ventral tegmental area function to social behaviors and identify mGluR1 modulation during postnatal development as a potential treatment strategy
Neurobiology of social behavior abnormalities in autism and Williams syndrome
Social behavior is a basic behavior mediated by multiple brain regions and neural circuits, and is crucial for the survival and development of animals and humans. Two neuropsychiatric disorders that have prominent social behavior abnormalities are autism spectrum disorders (ASD), which is characterized mainly by hyposociability, and Williams syndrome (WS), whose subjects exhibit hypersociability. Here we review the unique properties of social behavior in ASD and WS, and discuss the major theories in social behavior in the context of these disorders. We conclude with a discussion of the research questions needing further exploration to enhance our understanding of social behavior abnormalities
Communication Impairments in Mice Lacking Shank1: Reduced Levels of Ultrasonic Vocalizations and Scent Marking Behavior
Autism is a neurodevelopmental disorder with a strong genetic component. Core symptoms are abnormal reciprocal social interactions, qualitative impairments in communication, and repetitive and stereotyped patterns of behavior with restricted interests. Candidate genes for autism include the SHANK gene family, as mutations in SHANK2 and SHANK3 have been detected in several autistic individuals. SHANK genes code for a family of scaffolding proteins located in the postsynaptic density of excitatory synapses. To test the hypothesis that a mutation in SHANK1 contributes to the symptoms of autism, we evaluated Shank1−/− null mutant mice for behavioral phenotypes with relevance to autism, focusing on social communication. Ultrasonic vocalizations and the deposition of scent marks appear to be two major modes of mouse communication. Our findings revealed evidence for low levels of ultrasonic vocalizations and scent marks in Shank1−/− mice as compared to wildtype Shank1+/+ littermate controls. Shank1−/− pups emitted fewer vocalizations than Shank1+/+ pups when isolated from mother and littermates. In adulthood, genotype affected scent marking behavior in the presence of female urinary pheromones. Adult Shank1−/− males deposited fewer scent marks in proximity to female urine than Shank1+/+ males. Call emission in response to female urinary pheromones also differed between genotypes. Shank1+/+ mice changed their calling pattern dependent on previous female interactions, while Shank1−/− mice were unaffected, indicating a failure of Shank1−/− males to learn from a social experience. The reduced levels of ultrasonic vocalizations and scent marking behavior in Shank1−/− mice are consistent with a phenotype relevant to social communication deficits in autism.National Institute of Mental Health (U.S.) (Intramural Research Program)Simons Foundatio
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