Anencefalia numa perspectiva ética Anencephalia from an ethical perspective

Este artigo consta de uma revisão sumariada da anencefalia, um grave defeito embrionário do sistema nervoso central, sob o ponto de vista bioético, fundamentada em conhecimentos da embriologia e biologia celular modernas. Este tema tem sido alvo de debates acirrados em diversos setores da sociedade brasileira, visto que suscita grande interesse ao envolver a questão do abortamento, noções religiosas e de trazer à baila a questão dos direitos femininos, em face da possibilidade de se conceder à mulher a decisão de continuar ou não a gestar feto anencéfalo.<br>This article presents a brief review of anencephalia, a serious fetal defect of the central nervous system, from a bioethical point of view, founded on knowledge in modern embryology and cell biology. This issue has been the subject of much heated debate in many sectors of Brazilian society, as it touches on the question of abortion, religious beliefs and women's rights, regarding the woman's decision to continue an anencephalic pregnancy or not

Consensus guidelines for diagnosis, treatment and follow-up of patients with pancreatic cancer in Spain

The management of patients with pancreatic cancer has advanced over the last few years. We convey a multidisciplinary group of experts in an attempt to stablish practical guidelines for the diagnoses, staging and management of these patients. This paper summarizes the main conclusions of the working group. Patients with suspected pancreatic ductal adenocarcinoma should be rapidly evaluated and referred to high-volume centers. Multidisciplinary supervision is critical for proper diagnoses, staging and to frame a treatment plan. Surgical resection together with chemotherapy offers the highest chance for cure in early stage disease. Patients with advanced disease should be classified in treatment groups to guide systemic treatment. New chemotherapeutic regimens have resulted in improved survival. Symptomatic management is critical in this disease. Enrollment in a clinical trial is, in general, recommended