9 research outputs found

    The Reconstruction of the Object Surface using Confocal Microscope with Hyperchromatic Lens

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    The usage of a tandem-scanning reflected-light microscope is not common but this technology offers the wide possibilities in the area of the surface reconstruction. This article presents a method that can reconstruct the 3D relief from a single image with a known calibrated set of images. The method uses the property that the points in the same height are visualized in the same color and we propose the nonlinear optimization to find this dependence. Subsequently, the low brightness parts are added by circular partial convolution

    The flow of micrometre-sized glass fibres in a replica of the human trachea

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    Inhaled fibres can potentially cause inflammation of the lung tissue and interstitium which, after long-term exposure, may lead to lung cancer, malignant mesothelioma or pulmonary and pleural fibrosis. For risk reduction and correct setting of occupational hygiene regulations, it is important to be able to precisely calculate the fate of inhaled fibres depending on their physical characteristics and inhalation conditions. As there is a lack of experimental data on the orientation of fibres, a new test rig has been assembled for visualization and recording of flowing fibres in a replica of the human trachea. Fibres prepared from regular glass fibres produced commercially for blown thermal insulation have been processed, dispersed and introduced into the glass tube with dimensions of the trachea. Visualization was performed using a powerful LED light and a high-speed camera. Angles of the fibres have been evaluated for six different flowrates and the dependence of the angles on the flow Reynolds number was searched for. The angles of fibres agreed with expected values, i.e. only vertically and horizontally oriented fibres were recorded. However, the number of vertically and horizontally oriented fibres did not seem to be correlated with the flow Reynolds number

    Spindle Cell Hemangioma and Atypically Localized Juxtaglomerular Cell Tumor in a Patient with Hereditary BRIP1 Mutation: A Case Report

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    Spindle cell hemangioma is a benign vascular tumor typically occurring in the dermis or subcutis of distal extremities as red–brown lesions that can grow in both size and number over time. They can be very painful and potentially disabling. A family history of cancer or previous history may be relevant and must be taken into consideration. Juxtaglomerular cell tumor (reninoma) is an extremely rare cause of secondary hypertension diagnosed mostly among adolescents and young adults. Excessive renin secretion results in secondary hyperaldosteronism. Subsequent hypokalemia and metabolic alkalosis, together with high blood pressure, are clues for clinical diagnosis. Histological examination of the excised tumor leads to a definitive diagnosis. Reninoma is found in subcapsular localization, in most cases as a solitary mass, in imaging studies of kidneys. Exceptionally, it can be located in another part of a kidney. Both spindle cell hemangioma and reninoma are extremely rare tumors in children and adolescents. Herein, the authors present a case report of a patient with hereditary BRCA1 interacting protein C-terminal helicase 1 (BRIP1) mutation, spindle cell hemangioma, and secondary hypertension caused by atypically localized reninoma
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