Striving and competing and its relationship to self-harm in young adults.

Previous research has found that competitive, insecure striving (striving to avoid inferiority) has strong links with psychopathologies, self-harm and appearance anxiety. However, with rates of self-harm in young people rising, it seems important to explore the link between competitive striving and self-harm in young adults. Ninety-two participants completed a series of questionnaires which measured striving to avoid inferiority, self-harm, psychopathologies, social comparison, goal orientation and self-ideals. The results showed that competitive insecure striving was a key predictor of self-harm, depression, anxiety and stress.Mental Health Research Uni

Evaluation of a web-based self-compassion intervention to reduce student assessment anxiety.

Assessment anxiety is associated with excessive worry and cognitive disruption which can contribute to academic failure. Compassion-focused interventions have previously been effective in reducing anxiety, stress and depression among the general population. Aims: This study extended this approach to students whose academic achievement is potentially compromised by assessment anxiety, by evaluating a web-based compassionate imagery intervention. Students (n=48) who self-identified as assessment anxious were randomised to practice either compassionate imagery exercises or to a control condition of practicing relaxation exercises. Students completed measures of test anxiety, mastery and performance learning goals, self-compassion, self-criticism/self-reassurance, depression, anxiety and stress, before and after the two-week intervention. The compassionate imagery exercises improved self-compassion more than the control condition of relaxation exercises did. Both tasks improved students’ wellbeing, and reduced assessment anxiety among those with higher baseline assessment anxiety. Web-based compassionate imagery and relaxation may offer cost-effective interventions for reducing assessment anxiety. More research is needed on the influence of self-compassion on learning processes and academic performance and achievement.University of Derby Research for Learning and Teaching Fund (RLTF

Fears of compassion in a depressed population: Implication for psychotherapy

Background: While psychological therapies for depression have advanced in the last 20 years, still many people respond only partially and remain vulnerable to relapse. Insight into the limitations of our psychological therapies might be obtained from recent research that has revealed, in nonclinical populations, that some people can be fearful of positive emotions especially affiliative and compassion-focused ones. Aims: This study explores the fears of compassion in a clinical population and their associations with selfcriticism, self-compassion and depression, anxiety and stress. Method: 53 depressed patients completed a series of self-report scales. Results: Fears of compassion, particularly for oneself and from others, were strongly linked to self-criticism, depression, anxiety and stress, and negatively associated with self-compassion and self-reassurance. Conclusions: Since compassion and the affiliative emotions associated with compassion play a fundamental role in emotion regulation, individuals who are blocked or fearful of accessing these emotions are likely to be struggle with emotional regulation and the psychotherapeutic process. Research on the fears of compassion and affiliative emotions suggests these are important therapeutic targets.N/

Mechanical Behavior of Compression Molded Polyethylene Terephthalate

The purpose of this project was to investigate the effects of time, temperature, and pressure on the tensile strength and elastic modulus of recycled PET. Compression molding trials were performed on shredded PET bottles to produce tensile test specimens conforming to ASTM D638-03. Aluminum molds containing the PET were mechanically fastened together at the desired pressure and heated in an electric oven. The resulting specimens were subjected to tensile testing for analysis. This screening experiment failed to generate any statistically significant data concerning the factors of interest. These preliminary results may be used to design a more systematic follow-up study

Fears of negative emotions in relation to fears of happiness, compassion, alexithymia and psychopathology in a depressed population: A preliminary study

Abstract Objectives: While fears of negative or aversive emotions are linked to experiential avoidance and psychopathology, recent studies have also focused on the relation between psychopathology and fear of positive emotions. This study explores 1. which negative emotions of anger, anxiety and sadness on most feared and avoided and 2. the links between fears and avoidance of negative emotions, with fears of positive and affiliative emotions, alexithymia, and self-reported depression anxiety and stress. Method: A new scale was developed to measure fears of three negative emotions anxiety anger and sadness. 52 participants suffering from moderate to severe depression completed this measure, along with fear of happiness, fears of compassion, alexithymia and psychopathology. Results: Interestingly fears of negative emotions were not correlated with each other; in other words one can be frightened of one negative emotion but not another. The correlation between the fear of an emotion and the avoidance of that emotion was different for the three negative emotions, with fear of anger being the most strongly linked to its avoidance. Fear of sadness was the only feared ‘negative’ emotion associated with depression. Fear of sadness and fear of anger, but not anxiety also linked to fears of positive emotions and alexithymia. Conclusions: Fears of (so called) negative emotions vary in terms of the degree to which people are fearful of them and avoid them. Importantly it was sadness, a neglected emotion in the studies of emotion avoidance, which accounted for the higher proportion of variance for depression and alexithymia.N/

Styles of leadership, fears of compassion, and competing to avoid inferiority.

There is general agreement that styles of leadership evolved from mammalian group living strategies that form social ranks. In both non-human primates and humans, different styles of hierarchical dominant-subordinate and leader-follower behavior can be observed. These can be described in terms of dimensions of antisocial (relatively self-focused, aggressive and threat-based) and prosocial (relatively empathic, caring, and supportive) interpersonal styles. The aim of this study was to explore how a set of established self-report questionnaires might relate to these two dimensions. Two hundred and nineteen students completed questionnaires assessing ruthless self-advancement, coalition building, and dominant leadership styles, as well as hypercompetitiveness, narcissism, striving to avoid inferiority, compassion focused and ego focused goals, fears of compassion, social safeness and attachment (in)security. A principal component analysis supported an antisocial leadership style factor which comprised of ruthless self-advancement, narcissism and hypercompetitiveness. This was significantly correlated with fears of compassion, ego focused goals, insecure striving (striving to avoid inferiority), fears of losing out, fears of being overlooked, fears of being rejected, and avoidant relating in close relationships. It was significantly negatively correlated with compassionate goals. As the results did not reveal a clear factor solution for a prosocial leadership style, we chose to use the coalition building leadership style variable. This showed the opposite pattern, being significantly negatively correlated with narcissism, hypercompetitiveness, fears of compassion, fears of active rejection, and avoidance in close relationships. It was significantly positively correlated with secure striving, compassionate goals, and social safeness. We also found that fears of compassion for others was a partial mediator of the relationship between insecure striving with antisocial leadership style. Moreover, lower fears of compassion for the self emerged as a key mediator for the relationship between non-avoidant attachment with coalition building leadership style and, secure non-striving with coalition building leadership style. While the motive to accumulate social power, resources and dominance may be linked to antisocial forms of leadership, the intensity of the drive may also be linked to unaddressed threats and fears of rejection and fears of compassion. Efforts to promote more ethical, moral and prosocial forms of leadership may falter if such fears are left unaddressed.This research was supported by a donation received by the Compassionate Mind Foundation charity (https://compassionatemind.co.uk/) from Slimming World

How to increase ethical awareness in cybersecurity decision-making

Cybersecurity technologies offer secure channels to enable the confidentiality, integrity, and availability of data and services. Human factors; e.g. demographics, personality traits, and human values, which are linked with greater cybersecurity vulnerabilities, have drawn less attention. It is important to understand how to increase ethical awareness for cybersecurity professionals via training. This ethical awareness helps professionals make better moral judgments prior to final decisions and reduces the risk of unexpected human implications. To sensitise players to five cybersecurity ethical principles (beneficence, non-maleficence, justice, autonomy, and explicability), we created a serious game. This game allows players to explore multiple cybersecurity scenarios based on these five cybersecurity ethical principles. Although the analysis does not support the claim that the game increased ethical awareness in general, it did help promote better ethical understanding in some cases where players advanced from providing non-ethical to ethical justifications in a cybersecurity scenario after playing the game

Testing the neutral theory of molecular evolution using genomic data: a comparison of the human and bovine transcriptome

Despite growing evidence of rapid evolution in protein coding genes, the contribution of positive selection to intra- and interspecific differences in protein coding regions of the genome is unclear. We attempted to see if genes coding for secreted proteins and genes with narrow expression, specifically those preferentially expressed in the mammary gland, have diverged at a faster rate between domestic cattle (Bos taurus) and humans (Homo sapiens) than other genes and whether positive selection is responsible. Using a large data set, we identified groups of genes based on secretion and expression patterns and compared them for the rate of nonsynonymous (dN) and synonymous (dS) substitutions per site and the number of radical (Dr) and conservative (Dc) amino acid substitutions. We found evidence of rapid evolution in genes with narrow expression, especially for those expressed in the liver and mammary gland and for genes coding for secreted proteins. We compared common human polymorphism data with human-cattle divergence and found that genes with high evolutionary rates in human-cattle divergence also had a large number of common human polymorphisms. This argues against positive selection causing rapid divergence in these groups of genes. In most cases dN/dS ratios were lower in human-cattle divergence than in common human polymorphism presumably due to differences in the effectiveness of purifying selection between long-term divergence and short-term polymorphism

Antimicrobial effects of copper(II) bis(thiosemicarbazonato) complexes provide new insight into their biochemical mode of action

The copper(II) complexes of bis-thiosemicarbazones (Cu(btsc)) such as Cu(atsm) and Cu(gtsm) are neutral, lipophilic compounds that show promise as therapeutics for the treatment of certain neurological diseases and cancers. Although the effects of these compounds have been described at the cellular level, there is almost no information about their biochemical mode of action. In this work, we showed that Cu(atsm) and Cu(gtsm) displayed antimicrobial activities against the human obligate pathogen Neisseria gonorrhoeae that were more than 100 times more potent than Cu(NO3)2 salt alone. Treatment with Cu(btsc) also produced phenotypes that were consistent with copper poisoning, but the levels of intracellular copper were undetectable by ICP MS. We observed that Cu(btsc) interacted with proteins in the cell membrane. Systematic measurements of O2 uptake further demonstrated that treatment with both Cu(atsm) and Cu(gtsm) led to dose-dependent inhibition of respiratory electron transfer processes via succinate and NADH dehydrogenases. These dehydrogenases were not inhibited by a non-btsc source of CuII. The results led us to conclude that the biochemical mechanism of Cu(btsc) action is likely more complex than the present, simplistic model of copper release into the cytoplasm